A COMPARITIVE STUDY TO EVALUVATE THE EFFICACY OF AMLODIPINE WITH BISOPROLOL IN HYPERTENSIVE PATIENTS

Abstract

Aim and Objectives: The main aim of this study is to evaluate the efficacy of amlodipine and bisoprolol in hypertensive patients and to find out the
decreased level of blood pressure (BP)(systolic/diastolic) using amlodipine compared with bisoprolol in hypertensive patients.
Materials and Methods: This study which includes spontaneous prospective monitoring of hypertensive patients undergoing different types of
anti‑hypertensive treatments were carried out for a period of 6 months by us on both in-patient, as well as out-patients.
Result and Discussion: A total of 76 patients were screened. At the beginning of our study, 1st month reading was taken as the initial value and
6th month value was taken as the final value. Pre-treatment baseline of systolic BP was 154.7±6.1 mmHg and 156±6.7 mmHg in Group I and Group II
respectively. Patients receiving amlodipine had mean (±SD) reduction in systolic BP from baseline of 16.7±7.9 mmHg, whereas patients are receiving
bisoprolol had a reduction from baseline of 19±5.5 mmHg representing respective decrease of 10.8% and 12%. Treatment with both amlodipine and
bisoprolol therapy resulted in a significantly greater reduction in systolic BP.
Conclusion: The percentage reduction of systolic, as well as diastolic in the hypertensive patient, was more in bisoprolol treated group than
amlodipine treated. So which suggest that the bisoprolol is having a very good control over systolic and diastolic BP level and simultaneously it is
more beneficial for the treatment of hypertension.

Keywords: Amlodipine, Bisoprolol, Anti-hypertensives.