PRESCRIBING PATTERNS OF ANTIBIOTICS IN PAEDIATRICS FOR RESPIRATORY TRACT INFECTIONS/ DISORDERS IN TERTIARY CARE HOSPITAL
Abstract
ABSTRACT
Objectives: The main objective was to study the prescribing practice of antibiotic in hospital in-patient is to assess the prescribing patterns
of antibiotics in children who were admitted in a tertiary care hospital regarding respiratory tract infections and to check out which category of
antibiotics are most prescribed.
Methods: The study which includes a retrospective monitoring of pediatrics undergoing treatment with diff types of antibiotics were carried out for
a period of 6 months both in-patient as well as outpatient.
Results and Discussion: A total of 50 patients were screened. The most common category of antibiotic prescribed is aminoglycosides (48%),
broad-spectrum antibiotics (29%), cephalosporins (14%), and fluoroquinolones (7%) macrolides (2%). 48% were admitted with common cough
and cold accompanied by fever, 24% with bronchopneumonia, 14% with bronchial asthma, 12% with bronchitis, 2% with pneumonia. The number
of antibiotics per prescription ampicillin with garamycin were 51%, cefuroxime with garamycin were 21%, ciprofloxacin with garamycin were
10%, cefotaxime with garamycin was 7%, ciprofloxacin with amoxicillin was 2%, single antibiotic prescribed are cefuroxime (2%), garamycin
(4%), ciprofloxacin (4%). Adverse drug events were detected in sample size n=50 were 6% for drugs with ampicillin (rashes *4 days), ciprofloxacin
(loose stools *2 days).
Conclusion: In order to reduce the risk of antibiotic resistance of microbes, an antibiotic policy should be carefully instituted and implemented. The
doses prescribed to the pediatrics should be calculated according to the weights in order to avoid adverse drug reactions.
Keywords: Antibiotics, paediatrics, infections
Downloads
References
REFERENCES
Ghai OP. Essential Pediatrics. 4th ed. New Delhi, India: Interprint; 2002.
Sanz EJ, Bergman U, Dahlstorm M. Paediatric drug prescribing. Eur J
Clinpharmacol 1989;37:65-8.
Summers RS, Summers B. Drug prescribing in paediatrics. Ann Trop
Paediatr 1986;6:129-33.
Principle N, Sher D, Moresco RC, Marchisio P, Boccazzi A, Viola G,et al. Control of antibiotic therapy in paediatric patients. Dev Pharmacol
Ther 1981;2(3):145-55.
Schollenberg E, Albritton WL. Antibiotic misuse in a paediatric
teaching hospital. Can Med Assoc J 1980;122(1):49-52.
Isturiz RE, Carbon C. Antibiotic use in developing countries. Infect
Control Hosp Epidemiol 2000;21(6):394-7, 947.
National Drug Policy. 2005- Federal Republic of Nigeria. 2nd.
Abuja‑Nigeria: The Federal Ministry of Health Nigeria, WHO; 2005.
p. 1-17.
Pneumonia: Emerging Trends in Diagnosis & Care- First Published:
July 6, 2006 Revised: July 6, 2009 Revised: July 6, 2012.
Gonzales R, Bartlett JG, Besser RE, Cooper RJ, Hickner JM,
Hoffman JR, et al. Principles of appropriate antibiotic use for treatment
of uncomplicated acute bronchitis: Background. Ann Intern Med
;134(6):521-9.
Published
How to Cite
Issue
Section
The publication is licensed under CC By and is open access. Copyright is with author and allowed to retain publishing rights without restrictions.