BACTERIOLOGICAL PROFILE AND ANTIMICROBIAL RESISTANCE PATTERNS ISOLATES IN PUS SAMPLES AT AGARTALA GOVERNMENT MEDICAL COLLEGE

Authors

  • Arundhati Jamatia
  • Debasish Roy
  • Rubin Shil
  • Pranav Kumar Prabhakar Lovely Faculty of Applied Medical Sciences, Lovely Professional University

DOI:

https://doi.org/10.22159/ajpcr.2017.v10i1.15411

Abstract

Objective: Injudicious use of antibiotics in the management of pyogenic infections leads to emergence and spread of antibiotic resistance among pyogenic bacteria. This study aimed toward the determination of the bacterial isolates from pus samples and their antibiotic resistance pattern.

Methods: A retrospective analysis of 359 consecutive pus specimens received at Microbiology Department of Gobind Ballabh Pant Hospital under

Agartala Government Medical College, Agartala has been done. Bacterial isolates were identified by standard microbial techniques, and antibiotic susceptibility was done by modified Kirby-Bauer methods.

Results: Growth was seen in 176 (49.02%) specimens out of 359 samples. A total of 176 specimens yielded single isolate whereas 4 specimens yielded 2 isolates. Staphylococcus aureus was the most common organism isolated 53 (30.11%) followed by Pseudomonas spp. 37 (21.02%), Klebsiella spp. 30 (17.07%), Escherichia coli 24 (13.63%) Proteus spp. 11 (6.40%), Acinetobacter spp. 7 (3.97%), Citrobacter spp., and Enterobacter spp. 4 (2.27%) each. The highest number of multidrugs resistant isolates was Klebsiella spp. All S. aureus were 100% sensitive to vancomycin, and all Gram-negative bacilli were 100% to sensitive to imipenem and amikacin.

Conclusion: This study revealed the most common organism in pus samples is S. aureus followed by Pseudomonas spp. and highly multidrug resistance Klebsiella spp. Hence, continued monitoring of susceptibility pattern need to be carried out to detect the true burden of antibiotic resistance in organism and prevent their further emergence by judicious use of drugs.

Keywords: Pyogenic bacteria, Antibiotic resistance, Multidrug-resistant Klebsiella, Antibiotic policy.

 

Downloads

Download data is not yet available.

References

Jeffrey Stone A and Paul Cianci. Diabetic wounds. Diabetes Spectr 1997;4(2):118-23.

Krige JE, Beckingham JI. Liver abscesses and hydatid disease. Br Med J 2001;322:537.

Shea KW. Antimicrobial therapy for diabetic foot infections. A practical approach. Postgrad Med 1999;106(1):85-6, 89-94.

Agnihottri N, Gupta V, and Joshi RM. Aerobic bacterial isolates from burn wound infections and their Antibiograms - A five-years study. Burns 2004;30(3):241-3.

Rajan S. Skin and soft-tissue infections: Classifying and treating a spectrum. Cleve Clin J Med 2012;79(1):57-66.

Marton WJ, Nichols RL. Recognition, prevention, surveillance, and management of surgical site infections: Introduction to the problem and symposium overview. Clin Infect Dis 2001;33 Suppl 2:S67-8.

Sader HS, Jones RN, Silva JB; SENTRY Participants Group (Latin America). Skin and soft tissue infections in Latin American medical centers: Four-year assessment of the pathogen frequency and antimicrobial susceptibility patterns. Diagn Microbiol Infect Dis 2002;44(3):281-8.

Tiwari P, Kaur S. Profile and sensitivity pattern of bacteria isolated from various cultures in a Tertiary Care Hospital in Delhi. Indian J Public Health 2010;54(4):213-5.

Ghosh A, Karmakar PS, Pal J, Chakraborty N, Debnath NB, Mukherjee JD. Bacterial incidence and antibiotic sensitivity pattern in moderate and severe infections hospital patients. J Indian Med Assoc 2011;107(1):21-2, 24-5.

Zubair M, Malik A, Ahmad J. Clinico-microbiological study and antimicrobial drug resistance profile of diabetic foot infections in North India. Foot (Edinb) 2011;21(1):6-14.

Basu S, Ramchuran Panray T, Bali Singh T, Gulati AK, Shukla VK. A prospective, descriptive study to identify the microbiological profile of chronic wounds in outpatients. Ostomy Wound Manage

;55(1):14-20.

Published

01-01-2017

How to Cite

Jamatia, A., D. Roy, R. Shil, and P. K. Prabhakar. “BACTERIOLOGICAL PROFILE AND ANTIMICROBIAL RESISTANCE PATTERNS ISOLATES IN PUS SAMPLES AT AGARTALA GOVERNMENT MEDICAL COLLEGE”. Asian Journal of Pharmaceutical and Clinical Research, vol. 10, no. 1, Jan. 2017, pp. 335-7, doi:10.22159/ajpcr.2017.v10i1.15411.

Issue

Section

Original Article(s)