STUDY ON QUALITY OF LIFE ASSESSMENT IN DIABETIC RETINOPATHY AMONG PATIENTS WITH TYPE 2 DIABETES

Authors

  • Meenu Vijayan Deparment of Pharmacy, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Amrita University, Amrita Institute of Medical Science and Research Centre, Kochi, India.
  • Rose Jose Deparment of Pharmacy, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Amrita University, Amrita Institute of Medical Science and Research Centre, Kochi, India.
  • Sruthy Jose Deparment of Pharmacy, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Amrita University, Amrita Institute of Medical Science and Research Centre, Kochi, India.
  • Suja Abraham Deparment of Pharmacy, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Amrita University, Amrita Institute of Medical Science and Research Centre, Kochi, India.
  • Jintu Joy Deparment of Pharmacy, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Amrita University, Amrita Institute of Medical Science and Research Centre, Kochi, India.

DOI:

https://doi.org/10.22159/ajpcr.2017.v10i7.18095

Keywords:

Non-proliferative diabetic retinopathy, Proliferative diabetic retinopathy, Retinopathy

Abstract

Objective: The aim was to study the vision-related quality of life (QOL) for diabetic retinopathy (DR) among patients with Type 2 diabetes and to assess the direct medical cost of different treatment modalities.

Methods: It was based on an individual-based analysis of QOL before and after the treatment for DR. The main objective of the study was to compare QOL between patients based on the different treatment modalities using vision function questionnaire (VFQ)-25, to evaluate the direct medical cost for DR patients undergoing different treatment modalities and to compare the cost and QOL of different treatment modalities in samples with non-proliferative DR (NPDR)/proliferative diabetic retinopathy (PDR) macular edema. The population included were patients with Type 2 diabetes with NPDR, with clinically significant macular edema and PDR, patients diagnosed to have diabetes above 5-year duration, adult patients, ocular pain those who are on regular follow-up and those who are willing to be a part of study. A total of 256 patients were selected out, of which 141 patients were satisfied the study criteria and participated in the study. Data relevant to the voice-related QOL study were obtained and recorded using VFQ-25 questionnaire. Other data relevant to the study were obtained and recorded in a semistructured data collection form by interviewing the patient or their caregivers and by direct examination of patient's medical record. Expenditure was calculated in Indian Rupees.

Results: After comparing the baseline QOL with QOL after treatment, it was found that the overall QOL of the study samples in accordance with the treatment undergone was found to be improved. The overall QOL had improved after the treatment for all samples and major improvement was seen on dependency, social functioning (SF), and mental health (MH).

Conclusion: The overall QOL had improved after the treatment for all samples and major improvement were seen on dependency, SF, and MH. In conclusion, the study analyzed that intravitreal bevacizumab therapy is the cheapest one and with the comparatively same clinical outcome when compared with intravitreal ranibizumab therapy for macular edema cases in patients with NPDR and PDR.

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Author Biographies

Meenu Vijayan, Deparment of Pharmacy, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Amrita University, Amrita Institute of Medical Science and Research Centre, Kochi, India.

Department of pharmacy practice

Rose Jose, Deparment of Pharmacy, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Amrita University, Amrita Institute of Medical Science and Research Centre, Kochi, India.

Pharm D Regular

Sruthy Jose, Deparment of Pharmacy, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Amrita University, Amrita Institute of Medical Science and Research Centre, Kochi, India.

Pharm D Regular

References

Joseph TD, Robert LT, Gary CY. Pharmacotherapy a Pathophysiological Approach. 7th ed. New York, NY: McGraw-Hill Medical; 2008. p. 1205-8.

Balaiah S, Tirupa M, Narayana G, Mohanraj R, Reddy YP. Assessment of pharmaceutical care services on health related quality of life in patients with Type 2 diabetes mellitus. Int J Pharm Pharm Sci 2014;6(7):456-61.

Vijayan M, Nampoothiri V, Krishnan S, Vinod K, Vijayan N. Study on clinical pharmacists’ initiated interventions in improving compliance among geriatrics patients. Int J Pharm Sci Rev Res 2016;36(1):17-21.

Klein R, Klein BE, Moss SE. Prevalence and risk of diabetic retinopathy where age at diagnosis is 30 or more years. Arch Ophthalmol 1984;102(4):527-32.

Hanna AK, Roy M, Zinman B, McCulloch JC, Mortimer C, Falk JA, et al. An evaluation of factors associated with proliferative diabetic retinopathy. Clin Invest Med 1985;8(2):109-16.

Kertes PJ, Johnson TM, et al. Evidence Based Eye Care. 1st ed. Philadelphia, PA: Lipincott Williams; 2007. p. 403-41.

Tapp RJ, Shaw JE, Harper CA, de Courten MP, Balkau B, McCarty DJ, et al. The prevalence of and factors associated with diabetic retinopathy in the Australian population. Diabetes Care 2003;26(6):1731-7.

Singh R, Ramasamy K, Abraham C, Gupta V, Gupta A. Diabetic retinopathy: An update. Indian J Ophthalmol 2008;56(3):178-88.

Rasmieh M, Khader Y, Malas S, Abu-Yaghi N, Al-Bdour M, Ajlouni K, et al. Prevalence and risk factors of diabetic retinopathy among Jordanian patients with Type 2 diabetes mellitus. J Ophthalmol 2008;24(1):29-35.

Simó R, Hernández C. Advances in the medical treatment of diabetic retinopathy. Diabetes Care 2009;32(8):1556-62.

Andayani TM, Ibrahim MI, Asdie AH. The association of diabetes - Related factor and quality of life in Type 2 diabetes mellitus. Int J Pharm Pharm Sci 2010;2(1):139-45.

Published

01-07-2017

How to Cite

Vijayan, M., R. Jose, S. Jose, S. Abraham, and J. Joy. “STUDY ON QUALITY OF LIFE ASSESSMENT IN DIABETIC RETINOPATHY AMONG PATIENTS WITH TYPE 2 DIABETES”. Asian Journal of Pharmaceutical and Clinical Research, vol. 10, no. 7, July 2017, pp. 116-9, doi:10.22159/ajpcr.2017.v10i7.18095.

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Original Article(s)