A PROSPECTIVE EVALUATION OF CAUSES AND TREATMENT OF INFERTILITY IN A TERTIARY CARE HOSPITAL, ERODE

Authors

  • Amala Baby Department of Pharmacy Practice, J.K.K Nattraja College of Pharmacy, Kumarapalayam - 638 183, Namakkal, Tamil Nadu, India
  • Anila A Varghese Department of Pharmacy Practice, J.K.K Nattraja College of Pharmacy, Kumarapalayam - 638 183, Namakkal, Tamil Nadu, India
  • Cindy Jose Department of Pharmacy Practice, J.K.K Nattraja College of Pharmacy, Kumarapalayam - 638 183, Namakkal, Tamil Nadu, India
  • Krishnaveni Kandasamy Department of Pharmacy Practice, J.K.K Nattraja College of Pharmacy, Kumarapalayam - 638 183, Namakkal, Tamil Nadu, India
  • Shanmuga Sundaram Rajagopal Department of Pharmacology, J.K.K Nattraja College of Pharmacy, Kumarapalayam - 638 183, Namakkal, Tamil Nadu, India.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i2.22108

Keywords:

Infertility, Polycystic ovarian disease, Oligoasthenoteratozoospermia

Abstract

 Objective: Infertility has a serious impact on the psychosocial well-being of women in the developing world. The objective of the study was to evaluate the causes and treatment pattern of infertility patients in a tertiary care hospital.

Methods: The prospective observational study focused on the sociodemographic properties of infertile patients, causes of infertility, and various treatments carried out in a tertiary care hospital, Erode, Tamil Nadu.

Results: Of 200 cases, the majority was due to female factor (45.5%), followed by male factors (26%), both gender factors (25.5%), and unexplained etiology (6%). It was observed that major causes of male infertility (MI) were oligoasthenoteratozoospermia (OATS - 48.42%), followed by asthenozoospermia (17.89%), azoospermia (11.57%), erectile dysfunction (7.36%), oligoasthenozoospermia (5.26%), varicocele (3.15%), oligospermia (2.10%), necrozoospermia (2.10%), asthenoteratozoospermia (1.05%), and asthenozoospermia+erectile dysfunction (1.05%). In cases of female infertility (FI), the pattern of causes was polycystic ovarian disease (PCOD) (29.6%), followed by tubular block (13.23%), cyst (6.66%), hypothyroidism (4.44%), endometriosis (4.44%), hormonal problems (4.44%), fibroid (3.7%), fibroid+cyst (3.7%), premature ovarian failure (2.96%), thin endometrium (2.96%), multifollicularovary (2.96%), PCOD+hormonalproblems (2.96%), and hypothyroidism+hormonal problems (2.22%). Intrauterine insemination was the most commonly assisted reproductive technology employed, followed by in vitro fertilization and intracytoplasmic sperm injection. Of 200 infertile couples, 57 (28.5%) were unable to conceive within 6 months and 72 (36%) after 6 months following first consultation, 44 (22%) defaulted/lost follow-up/were still under consultation, 13 (6.5%) conceived with the help of assisted reproductive treatment, 10 (5%) conceived with the help of drug treatment, anddd 4 (2%) had spontaneous pregnancy.

Conclusion: The major cause of infertility was found to be PCOD in females and OATS in males. The most commonly prescribed drugs were antioxidants for males and progesterone for females.

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Author Biographies

Amala Baby, Department of Pharmacy Practice, J.K.K Nattraja College of Pharmacy, Kumarapalayam - 638 183, Namakkal, Tamil Nadu, India

Professor and Vice Principal,

Department of Pharmacology,

J.K.K Nattraja College of Pharmacy

Anila A Varghese, Department of Pharmacy Practice, J.K.K Nattraja College of Pharmacy, Kumarapalayam - 638 183, Namakkal, Tamil Nadu, India

Department of Pharmacy Practice,

J.K.K Nattraja College of Pharmacy, Kumarapalayam,

Tamil Nadu, India.

Cindy Jose, Department of Pharmacy Practice, J.K.K Nattraja College of Pharmacy, Kumarapalayam - 638 183, Namakkal, Tamil Nadu, India

Department of Pharmacy Practice,

J.K.K Nattraja College of Pharmacy, Kumarapalayam,

Tamil Nadu, India.

Krishnaveni Kandasamy, Department of Pharmacy Practice, J.K.K Nattraja College of Pharmacy, Kumarapalayam - 638 183, Namakkal, Tamil Nadu, India

Department of Pharmacy Practice,

J.K.K Nattraja College of Pharmacy, Kumarapalayam,

Tamil Nadu, India.

Shanmuga Sundaram Rajagopal, Department of Pharmacology, J.K.K Nattraja College of Pharmacy, Kumarapalayam - 638 183, Namakkal, Tamil Nadu, India.

Department of Pharmacy Practice,

J.K.K Nattraja College of Pharmacy, Kumarapalayam,

Tamil Nadu, India.

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Published

01-02-2018

How to Cite

Baby, A., A. A Varghese, C. Jose, K. Kandasamy, and S. S. Rajagopal. “A PROSPECTIVE EVALUATION OF CAUSES AND TREATMENT OF INFERTILITY IN A TERTIARY CARE HOSPITAL, ERODE”. Asian Journal of Pharmaceutical and Clinical Research, vol. 11, no. 2, Feb. 2018, pp. 149-53, doi:10.22159/ajpcr.2018.v11i2.22108.

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