SURVEILLANCE OF APPENDICECTOMY SPECIMEN WITH HISTOMORPHOLOGICAL EVALUATION
Keywords:Appendicitis, Appendicectomy, Mucocele, Endometriosis
Objective: Appendicectomy is the gold standard treatment in acute appendicitis, and in each case, a specimen should be evaluated thoroughly by a histopathologist to confirm the diagnosis and any unknown pathology. The present study aims to find out age and gender prevalence of appendicitis in a tertiary care hospital in Eastern India and various histological changes in the appendix in routine appendicectomy specimen undergoing surgery for appendicitis.
Methods: A total of 780 appendicectomy specimens were studied for acute appendicitis for 2 years. Gender prevalence and age-wise incidence of appendicitis were analyzed statistically. Sections were taken from different parts of formalin-fixed appendix specimen. A thorough histological examination was done to confirm acute appendicitis and to detect any incidental unusual histological changes.
Results: Of 780 cases, 343 (44%) were male and 437 (56%) were female. Females are more in number than males (p<0.001). The incidence was more common in the age group of 21â€“30 years (50.7%). Histological findings revealed normal vermiform appendix in 60 (7.7%), lymphoid hyperplasia in 75 (9.6%) cases, acute appendicitis and periappendicitis in 471 (60%) and 110 (14%) cases, respectively. Gangrenous appendicitis was found in 56 (7%) cases. Unexpected findings were reported in 8 (1.02%) cases, of which Enterobius vermicularis 2 (0.25%) cases, endometriosis 2 (0.25%) cases, mucocele 1 (0.12%) case, and carcinoid in 3 (0.4%) cases.
Conclusions: Apart from intraoperative examination, a routine histological study of biopsy specimen reveals at times rare pathological changes which has some impact on clinical co-relation and patient management and might help to avoid any lethal complications.
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