LANNEA DISCOLOR: ITS BOTANY, ETHNOMEDICINAL USES, PHYTOCHEMISTRY, AND PHARMACOLOGICAL PROPERTIES
DOI:
https://doi.org/10.22159/ajpcr.2018.v11i10.27523Keywords:
Alternative, complementary and traditional medicine, Anacardiaceae, Ethnopharmacology, Lannea discolor, Southern AfricaAbstract
Lannea discolor is an important component of the traditional, complementary, and alternative medicine health-care systems in several countries. This study is aimed at reviewing the botany, ethnomedicinal uses, phytochemical and biological activities of L. discolor. Information on its botany, medicinal uses, chemistry and pharmacological properties was undertaken using electronic databases such as Pubmed, SCOPUS, Medline, SciFinder, ScienceDirect, Google Scholar, EThOS, ProQuest, OATD and Open-thesis. Pre-electronic literature was sourced from the University Library. The species is used as herbal medicine for 24 human diseases. The major diseases and ailments treated using concoctions prepared from L. discolor include gastrointestinal problems, gonorrhea, infertility in women, convulsions, dizziness, injury, and wounds. Different aqueous and organic extracts of L. discolor exhibited anthelmintic, antibacterial, antimycobacterial, antifungal, antioxidant, antiplasmodial, and nematicidal activities. Detailed studies on the phytochemistry, pharmacological, and toxicological properties of L. discolor are required to correlate the medicinal uses of the species with its phytochemistry and pharmacological properties.
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References
World Health Organization. Traditional, Complementary and Integrative Medicine; 2017. Available from: http://www.who.int/ traditional-complementary-integrative-medicine/about/en/.
World Health Organization. WHO Traditional Medicine Strategy 2002-2005; 2002. Available from: http://www.wpro.who.int/health_ technology/book_who_traditional_medicine_strategy_2002_2005.pdf.
Rates SM. Plants as source of drugs. Toxicon 2001;39:603-13.
Watt JM, Breyer-Brandwijk MG. The Medicinal and Poisonous Plants of Southern and Eastern Africa. Edinburgh: E and S Livingstone Ltd.; 1962.
Sofowora A. Medicinal Plants and Traditional Medicine in Africa. Chichester: Wiley; 1982.
Farnsworth NR, Akerele OA, Soejarto DD, Guo Z. Medicinal plants in therapy. Bull World Health Organ 1985;63:965-81.
Gelfand M, Mavi S, Drummond RB, Ndemera B. The Traditional Medicine Practitioner in Zimbabwe: His Principles of Practice and Pharmacopoeia. Gweru: Mambo Press; 1985.
Oliver-Bever B. Medicinal Plants of Tropical West Africa. Cambridge: Cambridge University Press; 1986.
Hedberg I, Staugård F. Traditional Medicine in Botswana: Traditional Medicinal Plants. Gaborone: Ipelegeng Publishers; 1989.
Cunningham AB. African Medicinal Plants: Setting Priorities at the Interface between Conservation. Paris: UNESCO; 1993.
Kokwaro JO. Medicinal Plants of East Africa. Nairobi: East Africa Literature Bureau; 1993.
Burkill HM. The Useful Plants of West Tropical Africa. London: Royal Botanic Gardens, Kew; 1995.
Hostettmann K, Marston A, Ndjoko K, Wolfender JL. The potential of African medicinal plants as a source of drugs. Curr Organic Chem 2000;4:973-1010.
Neuwinger HD. African Traditional Medicine: A Dictionary of Plant use and Applications. Stuttagart: Medpharm Scientific Publishers; 2000.
Arnold TH, Prentice GA, Hawker LC, Snyman EE, Tomalin M, Crouch NR, et al. Medicinal and Magical Plants of Southern Africa: An Annotated Checklist. Pretoria: Strelitzia 13, National Botanical Institute; 2002.
Gurib-Fakim A, Brendler T. Medicinal and aromatic plants of Indian Ocean Islands: Madagascar, Comores, Seychelles and Mascarenes. Stuttgart: Medpharm Scientific Publishers; 2004.
Van Wyk BE, Wink M. Medicinal Plants of the World. Pretoria: Briza Publications; 2004.
Elujoba A, Odeleye O, Ogunyemi C. Traditional medicine development for medicinal and dental primary health care delivery system in Africa. Afr J Trad Complem Altern Med 2005;2:46-61.
Schmelzer GH, Gurib-Fakim A. The Plant Resources of Tropical Africa 11(2): Medicinal Plants 2. Wageningen: Plant Resources of Tropical Africa; 2008.
Schmelzer GH, Gurib-Fakim A. The Plant Resources of Tropical Africa 11(2): Medicinal Plants 2. Wageningen: Plant Resources of Tropical Africa; 2013.
Van Wyk BE, Van Oudtshoorn B, Gericke N. Medicinal Plants of South Africa. Pretoria: Briza Publications; 2009.
Maroyi A. Ethnobotanical study of medicinal plants used by people in Nhema communal area, Zimbabwe. J Ethnopharmacol 2011;136:347 54.
Maroyi A. Garden plants in Zimbabwe: Their ethnomedicinal uses and reported toxicity. Ethnobot Res Appl 2012;10:45-57.
Maroyi A. Traditional use of medicinal plants in south-central Zimbabwe: Review and perspectives. J Ethnobiol Ethnomed 2013;9:31.
Dzoyem JP, Tshikalange E. Medicinal Plant Research in Africa. Oxford: Elsevier; 2013.
Kuete V. Medicinal Plant Research in Africa: Pharmacology and Chemistry. Oxford: Elsevier; 2013.
Iwu M. Handbook of African Medicinal Plants. Boca Raton: CRC Press; 2014.
Maroyi A, Mosina GK. Medicinal plants and traditional practices in peri-urban domestic gardens of the Limpopo province, South Africa. Indian J Indigen Knowl 2014;13:665-72.
Maroyi A, Cheikhyoussef A. A comparative study of medicinal plants used in rural areas of Namibia and Zimbabwe. Indian J Indigen Knowl 2015;14:401-6.
Van Wyk BE. A review of commercially important African medicinal plants. J Ethnopharmacol 2015;176:118-34.
Neffati M, Najjaa H, Mathé A. Medicinal and Aromatic Plants of the World: Africa. Vol. 3. Leide: Springer; 2017.
Athipornchai A. A review on Tabernaemontana spp.: Multipotential medicinal plant. Asian J Pharmaceut Clin Res 2018;11:45-53.
Maroyi A. Dicomaanomala sond.: A review of its botany, ethnomedicine, phytochemistry and pharmacology. Asian J Pharmaceut Clin Res 2018;11:70-7.
Long, C. Swaziland’s Flora: siSwati Names and Uses; Swaziland National Trust Commission: Mbambane, Swaziland, 2005; Available from: http://www.sntc.org.sz/index.asp. [Last accessed on 2017 Dec 11].
Van Wyk BE, Gericke N. People’s Plants: A Guide to Useful Plants of Southern Africa. Pretoria: Briza Publications; 2007.
Dzomba P, Chayamiti T, Togarepi E. Heavy metal content of selected raw medicinal plant materials: Implication for patient health. Bull Environ Pharmacol Life Sci 2012;1:28-33.
Christenhusz MJ, Byng JW. The number of known plants species in the world and its annual increase. Phytotaxa 2016;261:201-17.
Palmer E, Pitman N. Trees of Southern Africa Covering all Known Indigenous Species in the Republic of South Africa, South-West Africa, Botswana, Lesotho and Swaziland. Cape Town: Balkema; 1972.
Schmidt E, Lotter M, McCleland W. Trees and Shrubs of Mpumalanga and Kruger National Park. Johannesburg: Jacana Media; 2002.
Wannan BS. Analysis of generic relationships in anacardiaceae. Blumea 2006;51:165-95.
Pell SK, Mitchell JD, Miller AJ, Lobova TA. Anacardiaceae. In: Kubitzki K, editor. The Families and Genera of Vascular Plants: Flowering Plants Eucodicotssapindales, Cucurbitales and Myrtaceae. Vol. X. London: Springer; 2011. p. 7-50.
Palgrave CM. Keith Coates Palgrave Trees of Southern Africa. Cape Town: Struik Publishers; 2002.
Van Wyk BE, Van Wyk P. Field Guide to Trees of Southern Africa. Cape Town: Struik Publishers; 1997.
Fernandes RB, Fernandes A. Anacardiaceae. In: Exell AW, Fernandes A, Wild H, editors. Flora Zambesiaca: Mozambique, Malawi, Zambia, Rhodesia, Bechuanaland Protectorate. Vol. 2. London: Crown Agents for Overseas Governments and Administrations; 1966. p. 550-615.
Germishuizen G, Meyer NL. Plants of Southern Africa: An Annotated Checklist. Strelitzia 14. Pretoria: National Botanical Institute; 2003.
Setshogo MP, Venter F. Trees of Botswana: Names and distribution. Pretoria: Southern African Botanical Diversity Network Report No. 18; 2003.
Da Silva MC, Izidine S, Amude AB. A preliminary checklist of the vascular plants of Mozambique. Pretoria: Southern African Botanical Diversity Network Report No. 30; 2004.
Setshogo MP. Preliminary Checklist of the Plants of Botswana. Pretoria: Southern African Botanical Diversity Network Report No. 37; 2005.
Figueiredo E, Smith GF. Plants of Angola. Strelitzia 22. Pretoria: South African National Biodiversity Institute; 2008.
Hyde MA, Wursten BT, Ballings P, Palgrave CM. Flora of Zimbabwe: Species information: Lanneadiscolor (Sond.) England; 2018. Available from: https://www.zimbabweflora.co.zw/speciesdata/species.php?species_id=136520. [Last retrieved on 2018 Apr 13].
Fowler DG. Traditional Ila plant remedies from Zambia. Kirkia 2002;18:35-48.
Morris B. Chewa Medical Botany: A Study of Herbalism in Southern Malawi. Hamburg: Lit Verlag; 1996.
Bruschi P, Morganti M, Mancini M, Signorini MA. Traditional healers and laypeople: Aqualitative and quantitative approach to local knowledge on medicinal plants in Muda (Mozambique). J Ethnopharmacol 2011;138:543-63.
Chinsembu KC. Ethnobotanical study of plants used in the management of HIV/AIDS-related diseases in Livingstone, southern province, Zambia. Evid Based Complement Alternat Med 2016;2016:4238625.
Chinsembu KC, Hijarunguru A, Mbangu A. Ethnomedicinal plant sused by traditional healers in the management of HIV/AID Sop port unistic diseases in Rundu, Kavango East Region, Namibia. 2015. S Afr J Bot 2015;100:33-42.
Palgrave KC. The Trees of Central Africa. Salisbury: National Publications Trust; 1957.
Arnold HJ, Gulumian M. Pharmacopoeia of traditional medicine in Venda. J Ethnopharmacol 1984;12:35-74.
Mabogo DE. The Ethnobotany of the Vhavenda. MSc Dissertation, Pretoria: University of Pretoria; 1990.
Hutchings A, Scott AH, Lewis G, Cunningham AB. Zulu Medicinal Plants: An Inventory. Pietermaritzburg: University of Natal Press; 1996.
Chigora P, Masocha R, Mutenheri F. The role of indigenous medicinal knowledge (IMK) in the treatment of ailments in rural Zimbabwe: The case of Mutirikwi communal lands. J Sustain Dev Afr 2007;9:26-43.
Ndamba J, Nyazema N, Makaza N, Anderson C, Kaondera KC. Traditional herbal remedies used for the treatment of urinary schistosomiasis in Zimbabwe. J Ethnopharmacol 1994;42:125-32.
Kazembe T, Munyarari E, Charumbira I. Use of traditional herbal medicines to cure malaria. Bull Environ Pharmacol Life Sci 2012;1:63 85.
Maroyi A. Treatment of diarrhoea using traditional medicines: Contemporary research in South Africa and Zimbabwe. Afr J Tradit Complement Altern Med 2016;13:5-10.
Semenya SS, Maroyi A. Medicinal plants used by the Bapedi traditional healers to treat diarrhoea in the Limpopo Province, South Africa. J Ethnopharmacol 2012;144:395-401.
Van Puyvelde L, Geiser I, Rwangabo PC, Sebikali B. Rwandese herbal remedies used against gonorrhoea. J Ethnopharmacol 1983;8:279-86.
Mølgaard P, Nielsen SB, Rasmussen DE, Drummond RB, Makaza N, Andreassen J. Anthelmintic screening of Zimbabwean plants traditionally used against schistosomiasis. J Ethnopharmacol 2001;74:257-64.
Mabona U, Viljoen A, Shikanga E, Marston A, Van Vuuren S. Antimicrobial activity of southern African medicinal plants with dermatological relevance: From an ethno pharmacological screening approach, to combination studies and the isolation of a bioactive compound. J Ethnopharmacol 2013;148:45-55.
Kabongo-Kayoka PN, Eloff JN, Obi CL, McGaw LJ. Antimycobacterial activity and low cytotoxicity of leaf extracts of some African anacardiaceae tree species. Phytother Res 2016;30:2001-11.
Chakuma N, Chipurura B, Muchuweti M, Chitindingu K, Bhebhe M, Chagonda L. (2015). Total phenolic content, free radical scavenging and antioxidant potential of Lanneadiscolor (Sond.) Engl bark and root extracts. J Biologically Active Prod Nat 2015;5:71-7.
Clarkson C, Maharaj VJ, Crouch NR, Grace OM, Pillay P, Matsabisa MG, et al. In vitro antiplasmodial activity of medicinal plants native to or naturalised in South Africa. J Ethnopharmacol 2004;92:177-91.
Nyoni M, Muzemu S, Chinheya C, Mushayabasa T, Ncube B. Screening Indigenous Nematicidal Plants in Zimbabwe Against Meloidogyne javanica. Paper Presented at a Conference Held on the 14th-16th July 2015, Elephant Hills Resort, Victoria Fallls, Zimbabwe. Available from: http://www.ir.msu.ac.zw:8080/jspui/bitstream/11408/1319/1/muzemu.pdf.
Maroyi A. Use of ethnomedicinal herbs to treat and manage schistosomiasis in Zimbabwe: Past trends and future directions. In: Martinez JL, Munoz-Acevedo A, Rai M, editors. Ethnobotany: Application of Medicinal Plants. London: CPC Press; 2018. p. 36-47.
Becker K, Lohrmann J. Feed selection by goats on tropical semi-humid rangeland. Small Rum Res 1992;8:285-98.
Würger G, McGaw LJ, Eloff JN. Tannin content of leaf extracts of 53 trees used traditionally to treat diarrhoea is an important criterion in selecting species for further work. S Afr J Bot 2014;90:114-7.
Tchounwou PB, Yedjou CG, Patlolla AK, Sutton DJ. Heavy metal toxicity and the environment. In: Luch A, editor. Molecular, Clinical and Environmental Toxicology. Experientia Supplementum. Vol. 101. Basel: Springer; 2012. p. 133-64.
Chang LW, Magos L, Suzuki T. Toxicology of Metals. Boca Raton: CRC Press; 1996.
Street RA. Heavy metals in medicinal plant products: An African perspective. S Afr J Bot 2012;82:67-74.
Shaban NS, Abdou KA, Hassan NE. Impact of toxic heavy metals and pesticide residues in herbal products. Beni-SuefUniversity. J Basic Appl Sci 2016;5:102-6.
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