CORRELATION BETWEEN PHYTOESTROGENS INTAKE WITH TELOMERE LENGTH IN MINANGKABAU PREMENOPAUSAL WOMEN

Desmawati Desmawati; Delmi Sulastri; Yuniar Lestari; Jamsari Jamsari

doi:10.22159/ajpcr.2018.v11i11.29509

Authors

Desmawati Desmawati Department of Nutrition, Medical Faculty, Andalas University, Padang, West Sumatera, Indonesia.
Delmi Sulastri Department of Nutrition, Medical Faculty, Andalas University, Padang, West Sumatera, Indonesia.
Yuniar Lestari Departments of Public Health, Medical Faculty, Andalas University, Padang, West Sumatera, Indonesia.
Jamsari Jamsari Department of Genomic and Molecular Breeding, Andalas University, Padang, West Sumatera, Indonesia.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i11.29509

Keywords:

Phytochemical, Phytoestrogens, Telomere, Estradiol, Premenopausal, Minangkabau

Abstract

Objective: This study aimed to investigate the correlation between phytoestrogens intake with telomere length in premenopausal Minangkabau ethnicity women.

Methods: This cross-sectional study was conducted in Padang city, to 113 premenopausal Minangkabau ethnic 40â€“54 years old. Food intake data were obtained by an interview by trained enumerators using semi-quantitative food frequency questionnaire. Telomere examination was done from 3 ml of venous blood. Telomere length examination by modification of O'Callaghan and Fenech method. Estradiol level was measured by the ELISA technique.

Results: This research indicated an average telomere length was 554.79Â±426.81 bp, estradiol level was 149.47Â±52.26 pg/ml, and phytoestrogens intake was 37.95Â±32.25 mg/day. There were the differences between phytoestrogens intake and telomere length based on estradiol levels. Then, there was no significant correlation between phytoestrogens intake and telomere length.

Conclusion: There is no significant positive correlation between phytoestrogens intake and telomere length of premenopausal women in the Minangkabau ethnic.

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Author Biographies

Desmawati Desmawati, Department of Nutrition, Medical Faculty, Andalas University, Padang, West Sumatera, Indonesia.

department of nutrition, Medical faculty of Andalas University

Delmi Sulastri, Department of Nutrition, Medical Faculty, Andalas University, Padang, West Sumatera, Indonesia.

Department of Nutrition, Medical Faculty, Andalas University

Yuniar Lestari, Departments of Public Health, Medical Faculty, Andalas University, Padang, West Sumatera, Indonesia.

Departments of Public Health, Medical Faculty, Andalas University

Jamsari Jamsari, Department of Genomic and Molecular Breeding, Andalas University, Padang, West Sumatera, Indonesia.

Department of Genomic and Molecular Breeding, Faculty of Agriculture, Andalas University

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