NEWER ADVANCES IN MESENCHYMAL STEM CELL THERAPY

VANITA G KANASE; SHRUTI RAMESH SHETTIGAR

doi:10.22159/ajpcr.2020.v13i5.35999

Authors

VANITA G KANASE Department of Pharmacology, Oriental College of Pharmacy, Sector 2, Behind Sanpada Railway Station, Sanpada West, Navi Mumbai, Maharashtra, India.
SHRUTI RAMESH SHETTIGAR Department of Pharmacology, Oriental College of Pharmacy, Sector 2, Behind Sanpada Railway Station, Sanpada West, Navi Mumbai, Maharashtra, India.

DOI:

https://doi.org/10.22159/ajpcr.2020.v13i5.35999

Keywords:

Mesenchymal stem cells, Cytokines, Cardiomyocytes, Exosomes

Abstract

In the modern world, overcoming diseases are more challenging and newer ways are being discovered to give high quality of patient care, on the basis of scientific experimentation and applicative studies undertaken by various institutes and organizations. Mesenchymal stem cells (MSCs) are procured through many body origins usually by the placenta as well as the umbilical cord but other sources like bone core derived MSCs are also important as each source will give the cells its own characteristic features. MSCs play a very important role in the scenario with their multi-lineage potency that can either directly or indirectly by acting on cytokines or growth factors can cause cell regeneration process and hold great possibility of wound repair, treating spinal cord injuries, and treating auto immune diseases by immunomodulation. MSCs can give incredible help in case of bone, cartilage or tissue related defects, injuries or disorders that may be corrected or repaired through it. They can be employed in various heart related complications, bacterial activity, sepsis, liver dysfunctions, diabetes, and even prove useful in cancer. Various procedures either physiological or surgical are present including cell therapies, tissue, and osteo-engineering and immune targeted experimentations that can treat the diseases as well as ensure complete recovery.

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Author Biography

VANITA G KANASE, Department of Pharmacology, Oriental College of Pharmacy, Sector 2, Behind Sanpada Railway Station, Sanpada West, Navi Mumbai, Maharashtra, India.

HOD PHARMACOLOGY

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