Objective: Antifungal activity of total ethanolic extract and fractions of Usnea varieties were proved against Aspergillus niger, Penicillium digitatum, and Rhizopus nigricans fungi. Methods: To perform the study of relative antifungal activity (AFR), flu

DAYANNA CABRA GACHA; LUIS POMBO OSPINA; JANETH ARIAS PALACIOS; OSCAR RODRÍGUEZ AGUIRRE

doi:10.22159/ajpcr.2020.v13i10.38962

Authors

DAYANNA CABRA GACHA Universidad Distrital Francisco José de Caldas. Facultad de Ciencias y Educación, Bogotá, Colombia. https://orcid.org/0000-0002-9915-5816
LUIS POMBO OSPINA Fundación Universitaria Juan N. Corpas, Centro de investigación (GIFVTA) Bogotá, Colombia.
JANETH ARIAS PALACIOS Department of Microbiology, Industrial Microbiology Program, Industrial Environmental and Biotechnology Research Group, Pontificia Universidad Javeriana, Bogotá, Colombia.
OSCAR RODRÍGUEZ AGUIRRE Environmental Engineering Program, Faculty of Engineering, Research Group CHOC-IZONE, Universidad El Bosque, Bogotá, Colombia.

DOI:

https://doi.org/10.22159/ajpcr.2020.v13i10.38962

Keywords:

Aspergillus niger, Penicillium digitatum, Rhizopus nigricans, Relative antifungal activity AFR, Usnea varieties

Abstract

Objective: Antifungal activity of total ethanolic extract and fractions of Usnea varieties were proved against Aspergillus niger, Penicillium digitatum, and Rhizopus nigricans fungi.

Methods: To perform the study of relative antifungal activity (AFR), fluconazole and ketoconazole were used as standards. The inhibition coefficient 50 (IC50) for each extract and the fractions was determined.

Results: It was established that the highest activity was presented by the acetone fraction with a value of 58.53. In the study of antifungal activity, the fraction that presented the best activity against P. digitatum was ethanolic with a value of 44.33, while for R. nigricans was petrol extract, with a value of 75.35 and finally for A. niger was the total extract with a value of 35.48.

Conclusions: Comparing the values obtained from the extract and the different fractions resulted in the dichloromethane fraction showing the best values.

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