STUDY TO EVALUATE THE ACUTE KIDNEY INJURY IN PATIENTS WITH POISONING

Abstract

Objective: The goal of the study is to determine the pattern of dangerous material presence in the field, as well as how severely it affects kidney function and can result in death.

Methods: An observational study of patients hospitalized to the poison ward of tertiary care hospitals of Gwalior was planned. For data collection a structured questionnaire was used, which includes questions on demographic information, details of poisoned intake, and the time interval between ingestion and hospital admission.

Results: There are 79 instances of Celphos poisoning, 157 cases of organophosphorus poisoning, 67 cases of hair dye poisoning, 58 cases of rat killer poisoning, 51 cases of acid or alkali ingestion, 28 cases of alcohol intoxication, and 14 cases of Ethylene dibromide poisoning. Organophosphorus poisoning has the highest number of instances (157), whereas ethylene dibromide poisoning has the lowest number (14). Except in the situations of acid/alkali ingestion and ethylene dibromide ingestion, where the age range of 26–40 years was more involved, the majority of serious cases were in the 10–25 year old age group. Poisonings show male dominance over female dominance. Almost all poisonings result in a deranged renal profile; however, ethylene bromide poisoning has the greatest rate (21.4%), whereas celphos poisoning has the highest rate (28.37%) in terms of term mortality.

Conclusion: The findings show that organophosphorus toxicity, celphos poisoning, hair dye, and rat killer are all prevalent in Gwalior and the nearby region. Acute kidney damage was also detected in hair dye, celphos, organophosphorus, rat killer, and ethylene dibromide poisonings, with ethylene dibromide being the most common. Finally, celphos and Ethylene dibromide poisoning had the greatest fatality rates.