ROLE OF ULTRASONOGRAPHY-GUIDED FINE NEEDLE ASPIRATION CYTOLOGY IN HEPATIC LESIONS: A PROSPECTIVE AND OBSERVATIONAL STUDY AT A TERTIARY HEALTH-CARE CENTRE IN CENTRAL INDIA

RAVIKANT MAHALE; RATNAKAR NAMDEO; JYOTI MERAVI; SANDEEP THAKRE; VIJAY SHRIVASTAVA

doi:10.22159/ajpcr.2023.v16i4.47827

Authors

RAVIKANT MAHALE Department of Pathology, Chhindwara Institute of Medical Sciences, Chhindwara, Madhya Pradesh, India.
RATNAKAR NAMDEO Department of General Surgery, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
JYOTI MERAVI Department of Obstetrics and Gynecology, Chhindwara Institute of Medical Sciences, Chhindwara, Madhya Pradesh, India.
SANDEEP THAKRE Department of General Surgery, Chhindwara Institute of Medical Sciences, Chhindwara, Madhya Pradesh, India.
VIJAY SHRIVASTAVA Department of Pathology, NSCB Medical College, Jabalpur, Madhya Pradesh, India.

DOI:

https://doi.org/10.22159/ajpcr.2023.v16i4.47827

Keywords:

FNAC, Hepatic lesions, Cytology, Ultrasonography, Hepatocellular carcinoma, Metastasis

Abstract

Objectives: The liver is a common site for primary as well as secondary malignancies. Ultrasonography (USG)-guided fine needle aspiration cytology (FNAC) is a rapid, accurate, economical, and safe diagnostic procedure for various hepatic lesions. The aims of the study were to categorize and study the cytomorphological features of the hepatic lesions, study the age and sex distribution and analyzing cytological features of the hepatic lesions, and to evaluate the sensitivity, specificity, and diagnostic accuracy of USG-guided FNAC in diagnosing hepatic lesions.

Methods: A prospective and observational study of 64 patients with clinically and radiologically diagnosed hepatic lesions and referred for FNAC in department of pathology of a tertiary care hospital. USG-guided FNAC was performed in each patient and cytological features were analyzed.

Results: In our study, out of total 64 USG-guided FNAC of liver, metastasis was most common – 33 cases (51.56%), followed by primary hepatocellular carcinoma – 18 cases (28.12%), liver abscess – 6 cases (9.37%), and 7 cases (10.93%) were unsatisfactory smears.

Conclusion: USG-guided FNAC, in expert hands being simple, safe, quick, reliable, cost-effective, efficient, and easily available OPD-based procedure and with less number of complications, it has a very important role in accurate diagnosis of primary hepatocellular carcinoma, secondary malignant tumors of liver, and inflammatory lesions of liver.

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References

Holm HH, Gammelgaard J, Jensen F, Smith EH, Hillman BJ. Ultrasound in the diagnosis of a palpable abdominal mass. Gastrointest Radiol 1982;7:149-51.

Ahmad SS, Akhtar K, Akhtar SS, Nasir AA, Khalid M, Mansoor T. Ultrasound guided fine needle aspiration biopsy of abdominal masses. JK Sci 2006;8:200-4.

Vasilj A, Katović SK. Fine needle aspiration cytology of abdominal organs-ten-year single centre experience. Acta Clin Croat 2016;55:35-40.

Sapnagoel DH, Sharma M. Ultrasound guided fine needle aspiration cytology (FNAC) in diagnosis of space occupying lesions (SOL) of liver. J Evol Med Dent Sci 2014;3:7480-86.

Hemlatha AL, Sindhuram VS, Sushma S, Suma JK, Varna I,Aditya A. Ultrasoundguided FNAC of abdominal-pelvic masses-the pathologists’perspective. J Clin Diagn Res 2013;7:273-77.

Reddy AS, Andola SK. Fine needle aspiration cytology of intra-abdominal lesions. JCDR 2011;5:758-65.

Sanjay M, Sarvesh BM. FNAC as a diagnostic tool in paediatric and adolescent lesions. Indian J Pathol Oncol 2015;2:284-9. doi: 10.5958/2394-6792.2015.00029.0

Dosi S, Gupta G, Kawatra M, Chakrabarti PR, Agrawal P, Jain MR. Role of radiological-assisted cytology in intra-abdominal lesions: A 3 years’ experience in a tertiary care centre. Int J Appl Basic Med Res 2016;6:101-5.

Namshiker AA, De Sousa Rocha P, Pinto RG. Role of Fine needle aspiration cytology in the assessment of intra-abdominal and retroperitoneal lesions-a comparative study. Nat J Lab Med 2016:5:PO31-7.

Rajyalakshmi R, Rajani V. Ultrasound guided FNAC of focal lesions of liver. Indian J Pathol Oncol 2020;7:143-6.

Sumana BS, Muniyappa B. Ultrasonography guided fine needle aspiration cytology with preparation of cell blocks in the diagnosis of intra-abdominal masses. J Clin Diagn Res 2015;9:EC08-12.

Jha B, Shah R, Patel J. Effectiveness of image guided fine needle aspiration cytology in cases of deep seated lesions. Int J Med Sci Public Health 2013;2:439-42. doi: 10.5455/ijmsph.2013.2.465-468.

Wee A. Fine needle aspiration biopsy of the liver: Algorithmic approach and current issues in the diagnosis of hepatocellular carcinoma. CytoJournal. 2005;2:7. doi: 10.1186/1742-6413-2-7, PMID 15941489

Swamy MC, Arathi C, Kodandaswamy C Value of ultrasonography-guided fine needle aspiration cytology in the investigative sequence of hepatic lesions with an emphasis on hepatocellular carcinoma. J Cytol 2011;28:178-84.

Pilotti S, Rilke F, Alasio L, Garbagnati F. The role of fine needle aspiration in the assessment of renal masses. Acta Cytol 1988;32:1-10. PMID 3336946