CLINICAL STUDY OF TOPICAL APPLICATION OF PLATELET-RICH PLASMA IN MANAGEMENT OF CHRONIC WOUNDS AT A TERTIARY CARE CENTER

Authors

  • Monika Pareek Department of Surgery, Sardar Patel Medical College, Bikaner, Rajasthan, India.
  • Ashok Kumar Department of Surgery, Sardar Patel Medical College, Bikaner, Rajasthan, India.
  • DIWAN JAKHAR Department of Surgery, Sardar Patel Medical College, Bikaner, Rajasthan, India.
  • Sanjay Lodha Department of Surgery, Sardar Patel Medical College, Bikaner, Rajasthan, India.
  • Navratan Gahltot Department of Surgery, Sardar Patel Medical College, Bikaner, Rajasthan, India.

DOI:

https://doi.org/10.22159/ajpcr.2023.v16i12.48338

Keywords:

Chronic wounds, Healing, Platelet rich plasma

Abstract

Objective: To study the efficacy and safety of platelet-rich plasma in the management of chronic wounds when applied locally.

Methods: A hospital-based prospective study was conducted on 30 cases with the diagnosis of a chronic wound and fulfilling inclusion criteria by convenience sampling presented to surgical OPD and emergency in the study period of 12 months (December 2021 to November 2022) at the Dept. of Surgery, S.P. Medical College, and P.B.M. Hospital, Bikaner.

Results: The mean age was 48.76±5.65 years with male preponderance, and most of the cases were rural. 36.67% of cases presented in 6–12 months; 36.67% had traumatic etiology; 30% had diabetic; 26.67% had vascular; and 6.67% had burn etiology. 53.33% of cases had a lesion on the foot, and 22% of cases had joint involvement, with a mean size of an ulcer of 8.94±2.14 cm2. 73.33% of cases had partial healing, and 26.67% had complete healing. The mean duration for complete healing was 10.5±3.4 weeks. Mean dressings were needed for the complete healing were 21.1±5.9 dressings.

Conclusion: PRP was found to be useful in treating chronic ulcers. However, further controlled, randomized prospective clinical trials are necessary to definitively demonstrate its efficacy.

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Author Biographies

Monika Pareek, Department of Surgery, Sardar Patel Medical College, Bikaner, Rajasthan, India.

Resident, Department of Surgery,

Ashok Kumar, Department of Surgery, Sardar Patel Medical College, Bikaner, Rajasthan, India.

Professor, Department of Surgery

Sanjay Lodha, Department of Surgery, Sardar Patel Medical College, Bikaner, Rajasthan, India.

Assistant Professor, Department of Surgery

Navratan Gahltot, Department of Surgery, Sardar Patel Medical College, Bikaner, Rajasthan, India.

Resident, Department of Surgery

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Published

07-12-2023

How to Cite

Pareek, M., A. Kumar, D. JAKHAR, S. Lodha, and N. Gahltot. “CLINICAL STUDY OF TOPICAL APPLICATION OF PLATELET-RICH PLASMA IN MANAGEMENT OF CHRONIC WOUNDS AT A TERTIARY CARE CENTER”. Asian Journal of Pharmaceutical and Clinical Research, vol. 16, no. 12, Dec. 2023, pp. 43-46, doi:10.22159/ajpcr.2023.v16i12.48338.

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