• Mahadeva Rao Us Universiti Sultan Zainal Abidin,Kampus Kota, 20400 Kuala Terengganu, Terengganu.
  • Thant Zin Universiti Sultan Zainal Abidin.
  • Muhammad Abdurrazak Universiti Sultan Zainal Abidin.
  • Bashir Ado Ahmad Universiti Sultan Zainal Abidin.


Syringin, a phenylpropanoid glycoside belongs to eleutheroside derivative. This bioactive compound was identified in several plants including Musa
paradisiaca, Jasminum mesnyi, Edgeworthia chrysantha, Acanthopanax senticosus, etc. According to Nair et al., syringin is synthesized from the precursor
phenylalanine by a series of reactions. Zhao has described a rapid extraction method based on the ultrasound-assisted extraction of syringin from
the bark of Ilex rotunda thumb using response surface methodology. Based on the findings made by Jizhong et al., the bioactive compound syringin
was separated from the n-butanol extract of the stems and barks of E. chrysantha Lindl by high-speed counter-current chromatography. According
to Choi et al., the enrichment and purification of syringin from A. senticosus was performed based on the adsorption and desorption properties of
commercial macroporous resins. The pharmacological properties of syringin includes scavenging the free radicals, protection against neuronal cell
damage, inhibition of apoptosis, anti-diabetic effect, anti-inflammatory potential, anti-nociceptive action, anti-allergic effect, etc.
Keywords: Phenylpropanoid glycoside, Eleutheroside, Apoptosis, Nociceptive.


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Author Biographies

Mahadeva Rao Us, Universiti Sultan Zainal Abidin,Kampus Kota, 20400 Kuala Terengganu, Terengganu.

Professor,Faculty of Medicine.

Thant Zin, Universiti Sultan Zainal Abidin.

Medical Lecturer, Faculty of Medicine and Health Science.

Muhammad Abdurrazak, Universiti Sultan Zainal Abidin.

Masters Student, Faculty of Medicine and Health Science

Bashir Ado Ahmad, Universiti Sultan Zainal Abidin.

Masters Student, Faculty of Medicine and Health Science.


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How to Cite

Rao Us, M., T. Zin, M. Abdurrazak, and B. Ado Ahmad. “CHEMISTRY AND PHARMACOLOGY OF SYRINGIN, A NOVEL BIOGLYCOSIDE: A REVIEW”. Asian Journal of Pharmaceutical and Clinical Research, vol. 8, no. 3, May 2015, pp. 20-25,



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