• KALA K. JACOB Inter University Centre for Development of Marine Biotechnology, Cochin University of Science and Technology, Kerala, 682016 India
  • PRASHOB PETER K. J. Department of Chemical Oceanography, Cochin University of Science and Technology, Kerala, 682016 India
  • CHANDRAMOHANAKUMAR N. Inter University Centre for Development of Marine Biotechnology, Cochin University of Science and Technology, Kerala, 682016 India



Humic substances, Biomaterial, Drug delivery, Humic acid, Fulvic acid


Efficiency of therapeutic compounds could be enhanced by encapsulation and covalent attachments to a biomaterial carrier. Complex formation with humic substances is valuable techniques to improve bioactivity of natural products. Fractal structures of humic substances also have adjacent carboxyl and hydroxyl groups. Along with molecular bonding property, reduction-oxidation and association-dissociation capacities of humic substances are considered this as a biomaterial for transform, other molecules, and substances. Immune system responses of humic acid stimulates in the human body. However, pharmaceutical importance of humic substances, demands on evidenced efficacy and a clearly defined chemical composition of the preparations used. Toxicological safety standards also have to be evaluated. This review summarises the application of humic substances as pharmaceuticaly important biomaterial. Research on this zone opened up an application for humic substances in pharmacogonasy.


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How to Cite

JACOB, K. K., K. J., P. P., & N., C. (2019). HUMIC SUBSTANCES AS A POTENT BIOMATERIALS FOR THERAPEUTIC AND DRUG DELIVERY SYSTEM-A REVIEW. International Journal of Applied Pharmaceutics, 11(3), 1–4.



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