DRUG-RELATED PROBLEMS IN HOSPITALIZED GERIATRIC PATIENTS WITH DIABETES MELLITUS

Authors

  • Debby Dystra Maharani Department of Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia.
  • Nadia Farhanah Syafhan Department of Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia.
  • Yetti Hersunaryati Department of Pharmacy, Pharmacy Installation, Gatot Soebroto Army Hospital, Jakarta, 10410, Indonesia.

DOI:

https://doi.org/10.22159/ijap.2018.v10s1.30

Keywords:

Adverse reaction, Drug-related problem, Gatot Soebroto Army Hospital, Geriatric, Treatment effectiveness

Abstract

Objective: This study aimed at analyzing drug-related problems (DRPs) in hospitalized geriatric patients with diabetes mellitus.
Methods: We prospectively collected data of 26 hospitalized geriatric patients at the Gatot Soebroto Army Hospital (age, >60 year) who underwent
inpatient treatment for at least 1 month between February and April 2015. Readable data were obtained from prescriptions, medical records, and
index card/nurses records. We obtained data on 299 drug treatments for 26 patients and identified 166 DRPs. These were analyzed based on the
Pharmaceutical Care Network Europe Version 6.2.
Results: The percentage of treatment effectiveness (50.6%) and adverse drug reactions (49.4%) was predominantly due to an inappropriate drug–
drug or drug–food combination, including the incidence of drug interactions (20.4%).

Downloads

Download data is not yet available.

References

Indonesian Ministry of Health. Directorate of Community and Clinical

Pharmacy Development, Directorate General of Pharmaceutical and

Medical Devices, Indonesian Ministry of Health. Pharmaceutical Care

for Diabetes Mellitus. Jakarta: Indonesian Ministry of Health; 2005.

DiPiro JT, Talbert RL, Yee G, Matzke G, Wells B, Posey LM.

Pharmacotherapy: A Pathophysiologic Approach. 7th ed. United States

of America: McGraw-Hill; 2008.

Sievenpiper JL, Dworatzek PD. Food and dietary pattern-based

recommendations: An emerging approach to clinical practice guidelines

for nutrition therapy in diabetes. Can J Diabetes 2013;37:51-7.

Dennedy MC. Management of Type 1 diabetes mellitus. Medicine

;38:610-7.

Pharmaceutical Care Network Europe Foundation. PCNE Classification

for Drug related problems (revised 14-01-2010 vm) V6.2. Netherland:

Pharmaceutical Care Network Europe Foundation; 2010.

Indonesian Ministry of Health. Directorate of Community and Clinical

Pharmacy Development, Directorate General of Pharmaceutical and

Medical Devices, Indonesian Ministry of Health. Guideline on Drugs

Therapy Monitoring. Jakarta: Indonesian Ministry of Health; 2009.

Semla TP, Rochon PA, Cobbs EL, Duthie EH, Murphy JB.

Pharmacotherapy. In: Geriatrics Review Syllabus: A Core Curriculum

in Geriatric Medicine. Boston: Blackwell; 2005.

Hanlon JT, Schmader KE, Ruby CM, Weinberger M. Suboptimal

prescribing in older inpatients and outpatients. J Am Geriatr Soc

;49:200-9.

Fulton MM, Allen ER. Polypharmacy in the elderly: A literature review.

J Am Acad Nurse Pract 2005;17:123-32.

Hajjar ER, Cafiero AC, Hanlon JT. Polypharmacy in elderly patients.

Am J Geriatr Pharmacother 2007;5:345-51.

Björkman IK, Sanner MA, Bernsten CB. Comparing 4 classification

systems for drug-related problems: Processes and functions. Res Social

Adm Pharm 2008;4:320-31.

Indonesian Ministry of Health. Directorate of Community and Clinical

Pharmacy Development, Directorate General of Pharmaceutical and

Medical Devices, Indonesian Ministry of Health. Guideline on Visit.

Jakarta: Indonesian Ministry of Health; 2011.

Wright J. Complications of antibiotic therapy. Med Clin North Am

;97:356420.

Pawitan JA. Nerve and Mental Health Module. Jakarta: Faculty of

Medicine Universitas Indonesia; 2007.

Lester GD, Smith RL, Robertson ID. Effect of treatment with

omeprazole or ranitidine on gastric squamous ulceration in racing

through breds. J Am Vet Med Assoc 2005;227:1636-9.

Lai L, Gharib S. Pcv65 drug-drug interactions on angiotensin converting

enzyme (ace) inhibitor prescriptions in the United States: 2001 to 2004.

Value Health 2007;10:A55-6.

Shargel L, Wu-Pong Susanna BC, Yu A. Applied Biopharmaceutics

and Pharmakokinetics. New York: The McGraw-Hill Companies, Inc;

Published

20-12-2018

How to Cite

Maharani, D. D., Syafhan, N. F., & Hersunaryati, Y. (2018). DRUG-RELATED PROBLEMS IN HOSPITALIZED GERIATRIC PATIENTS WITH DIABETES MELLITUS. International Journal of Applied Pharmaceutics, 10(1), 142–147. https://doi.org/10.22159/ijap.2018.v10s1.30

Issue

Section

Original Article(s)

Most read articles by the same author(s)