EFFECTS OF EXTRA VIRGIN OLIVE OIL VERSUS RICE BRAN OIL ON GLYCEMIC CONTROL IN PATIENTS WITH TYPE-2 DIABETES MELLITUS
DOI:
https://doi.org/10.22159/ijap.2019.v11s6.33540Keywords:
Type 2 diabetes mellitus, Olive oil, Rice bran oil, Glucose level, Lipid levelAbstract
Objective: The purpose of this study was to determine the effect of extra virgin olive oil (EVOO) and rice bran oil (RBO) on glycemic control and lipid profiles in patients with type-2 diabetes mellitus (T2DM).
Methods: Ten patients with T2DM received 15 ml/day of EVOO or RBO. Levels of fasting blood glucose (FBG), postprandial blood glucose (PBG), total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), and triglycerides (TGs) were measured. RBO or EVOO was administered for 4 consecutive weeks. During a 2-week interval, the treatment was not administered. After this washout period, a crossover design was implemented by exchanging EVOO supplementation with RBO supplementation and vice versa for 4 consecutive weeks.
Results: Changes in levels of FBG, PBG, TC, LDL-C, and TGs were not significantly different in the two groups. However, significantly decreased the levels of HDL-C were observed in both groups.
Conclusion: RBO and EVOO had no significant influence on levels of FBG or PBG.
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References
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19. Lasa A, Miranda J, Bullo M, Casas R, Salas Salvado J, Larretxi I, et al. Comparative effect of two mediterranean diets versus a low-fat diet on glycaemic control in individuals with type 2 diabetes. Eur J Clin Nutr 2014;68:767–72.
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2. International Diabetes Federation. Cost-effective solutions for the prevention of type 2 diabetes. Brussels, Belgium; 2016. p. 1–68.
3. Harvey R. Lippincott’s illustrated reviews: Biochemistry. Lippincott, Williams and Wilkins; 2011. p. 337–48.
4. Appleton A. Metabolism and nutrition. 4th ed. Mosby, New York, NY, USA; 2013. p. 113–20.
5. American Diabetes Association, Bantle JP, Wylie-Rosett J, Albright AL, Apovian CM, Clark NG, et al. Nutrition recommendations and interventions for diabetes: a position statement of the American diabetes association. Diabetes Care 2008;31(Suppl 1):S68–S71.
6. PERKENI. Consensus pengendalian dan pencegahan diabetes mellitus type 2 di indonesia; 2015. p. 78.
7. International Olive Council. International trade standard applying to olive oils and olive-pomace oils. Available from: www.internationaloliveoil/documents/viewfile/3615-normaen-1. [Last accessed on 03 Dec 2018]
8. Ghanbari R, Anwar F, Alkharfy KM, Gilani AH, Saari N. Valuable nutrients and functional bioactive in different parts of olive (Olea europaea L.)–a review. Int J Mol Sci 2012;13:1291–340.
9. Cicerale S, Lucas L, Keast R. Biological activities of phenolic compounds present in virgin olive oil. Int J Mol Sci 2010;11:458–79.
10. Hao J, Shen W, Yu G, Jia H, Li X, Feng Z, et al. Hydroxytyrosol promotes mitochondrial biogenesis and mitochondrial function in 3T3-L1 adipocytes. J Nutr Biochem 2010;21:634–44.
11. Visioli F, Galli C. The role of antioxidants in the mediterranean diet. Lipid 2001;36(Suppl 1):S49–S52.
12. Visioli F, Bellomo G, Galli C. Free radical-scavenging properties of olive oil polyphenols. Biochem Biophys Res Commun 1998;247:60–4.
13. Mäkynen K, Chitchumroonchokchai C, Adisakwattana S, Failla ML, Ariyapitipun T. Effect of gamma-oryzanol on the bioaccessibility and synthesis of cholesterol. Eur Rev Med Pharmacol Sci 2012;16:49–56.
14. Rivellese AA, Giacco R, Annuzzi G, De Natale C, Patti L, Di Marino L, et al. Effects of monounsaturated vs. saturated fat on postprandial lipemia and adipose tissue lipases in type 2 diabetes. Clin Nutr 2008;27:133–41.
15. Carnevale R, Loffredo L, Del Ben M, Angelico F, Nocella C, Petruccioli A, et al. Extra virgin olive oil improves post-prandial glycemic and lipid profile in patients with impaired fasting glucose. Clin Nutr 2017;36:782–7.
16. Lai MH, Chen YT, Chen YY, Chang JH. Effects of rice bran oil on the blood lipids profiles and insulin resistance in type 2 diabetes patients. J Clin Biochem Nutr 2012;51:15–8.
17. Devarajan S, Chatterjee B, Urata H, Zhang B, Ali A, Singh R, et al. A blend of sesame and rice bran oils lowers hyperglycemia and improves the lipids. Am J Med 2016;129:731–9.
18. Violi F, Loffredo L, Pignatelli P, Angelico F, Bartimoccia S, Nocella C, et al. Extra virgin olive oil use is associated with improved post-prandial blood glucose and LDL cholesterol in healthy subjects. Nature 2015;5:e172-e177.
19. Lasa A, Miranda J, Bullo M, Casas R, Salas Salvado J, Larretxi I, et al. Comparative effect of two mediterranean diets versus a low-fat diet on glycaemic control in individuals with type 2 diabetes. Eur J Clin Nutr 2014;68:767–72.
20. Salas Salvado J, Bullo M, Estruch R, Ros E, Covas MI, Ibarrola Jurado N, et al. Prevention of diabetes with mediterranean diets: a subgroup analysis of a randomized trial. Ann Intern Med 2014;160:1–10.
21. Perona JS, Vogler O, Sanchez Dominguez JM, Montero E, Escriba PV, Ruiz-Gutierrez V. Consumption of virgin olive oil influences membrane lipid composition and regulates intracellular signaling in elderly adults with type 2 diabetes mellitus. J Gerontol A Biol Sci Med Sci 2007;62:256–63.
22. Chen CW, Cheng HH. A rice bran oil diet increases LDL-receptor and HMG-CoA reductase mRNA expressions and insulin sensitivity in rats with streptozotocin/nicotinamide-induced type 2 diabetes. J Nutr 2006;136:1472–6.
23. Liang Y, Gao Y, Lin Q, Luo F, Wu W, Lu Q, et al. A review of the research progress on the bioactive ingredients and physiological activities of rice bran oil. Eur Food Res Technol 2014;238:169–76.
24. Tiwari AK, Rao JM. Diabetes mellitus and multiple therapeutic approaches of phytochemicals: present status and future prospects. Curr Sci 2002;83:30–8.
25. Kuriyan R, Gopinath N, Vaz M, AV K. Use of rice bran oil in patients with hyperlipidemia. Natl Med J India 2006;18:292-6.
Published
15-12-2019
How to Cite
WIJAYANTHIE, N., GUNARTI, D. R., MANIKAM, N. R., & YULHASRI. (2019). EFFECTS OF EXTRA VIRGIN OLIVE OIL VERSUS RICE BRAN OIL ON GLYCEMIC CONTROL IN PATIENTS WITH TYPE-2 DIABETES MELLITUS. International Journal of Applied Pharmaceutics, 11(6), 56–59. https://doi.org/10.22159/ijap.2019.v11s6.33540
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