APPLICATION OF NANOANTIBIOTICS APPROACH AGAINST ANTI-BACTERIAL RESISTANCE

Authors

  • AYA YASEEN MAHMOOD ALABDALI University of Mashreq, College of Pharmacy, Baghdad, Iraq https://orcid.org/0000-0001-6903-360X
  • MARWAH SAMI KZAR University of Mashreq, College of Pharmacy, Baghdad, Iraq
  • SASIKALA CHINNAPPAN Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia https://orcid.org/0000-0002-7565-8662
  • RAVISHANKAR RAM MANI Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia
  • MALARVILI SELVARAJA Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia https://orcid.org/0000-0002-8085-3585
  • KOK JING WEN Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia
  • LAI SALLY Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia
  • FU WAI KUANG Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia

DOI:

https://doi.org/10.22159/ijap.2022v14i3.43508

Keywords:

Infectious disease, Antimicrobial agents, Drug resistance, Nanoantibiotics

Abstract

Despite the fact that we live in an era with unique and advanced technology for revealing underlying molecularly creating new drugs and disease mechanisms, infectious illnesses remain one of the world's major health issues. Antimicrobial agents now available against pathogenic microorganisms are insufficient to combat the problems posed by novel multidrug-resistant (MDR) infections. Antimicrobial drug restrictions are producing negative side effects and the development of multiple drug resistance. Drug resistance will necessitate the use of high-dose antibiotics, resulting in severe toxicity and the development of new medicines. Nanoantibiotics, a new type of antimicrobial agent that combines antimicrobial compounds with nanoparticles, has been created to solve these shortcomings. Additionally, previous reports stated that the pharmacokinetics profiles and have quicker ingestion in circulatory framework. In this subject, we will clarify the various sorts of nanoantibiotics, their instrument of activity, key targets and medication discharge components. We will likewise portray some significant microbial elements that will influence the activity of nanoantibiotics.

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Published

07-05-2022

How to Cite

MAHMOOD ALABDALI, A. Y., KZAR, M. S., CHINNAPPAN, S., RAM MANI, R., SELVARAJA, M., WEN, K. J., SALLY, L., & KUANG, F. W. (2022). APPLICATION OF NANOANTIBIOTICS APPROACH AGAINST ANTI-BACTERIAL RESISTANCE. International Journal of Applied Pharmaceutics, 14(3), 34–39. https://doi.org/10.22159/ijap.2022v14i3.43508

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