• CH. ANIL KUMAR University College of Pharmaceutical Sciences, Satavahana University, Karimnagar, Telangana, India
  • J. ASHWINI University College of Pharmaceutical Sciences, Satavahana University, Karimnagar, Telangana, India
  • ARCHANA G. L. University College of Pharmaceutical Sciences, Satavahana University, Karimnagar, Telangana, India
  • SEPURI VIJAYA LAXMI University College of Technology, Osmania University, Hyderabad, Telangana, India
  • ANIL KUMAR GARIGE Jayamukhi Institute of Pharmaceutical Sciences, Narsampet, Warrangal, Telangana, India
  • VIJITHA CHANDUPATLA Vaagdevi Institute of Pharmaceutical Sciences, Bollikunta, Warrangal, Telangana, India
  • M. AKIFUL HAQUE School of Pharmacy, Anurag University, Ghatkesar, Hyderabad, India
  • SHARUK L. KHAN MUPs College of Pharmacy (B Pharm), Degaon, Risod, Washim, Maharashtra, India



Transdermal patch, Angina pectoris, Solvent-casting method, Nitroglycerin


Topical delivery methods have been used since the dawn of time, employed to cure a wide range of ailments and for aesthetic purposes. Transdermal drug delivery has evolved throughout time, with the development of passive and active technologies that have resulted in enhanced distribution, accuracy in drug dosage, and better fulfilment of the requirements of the individual. The search for more powerful pharmaceuticals that can be delivered to the skin through appropriate transdermal technologies will continue to be a focus in the development of drugs for transdermal patches and other forms of delivery. Topical and transdermal distribution has been around for a while, but this review will focus on transdermal patches and how they've evolved. The articles have been searched on different search engines such as Scopus database, Science direct, PubMed, Google scholar, and Bentham science using multiple keywords. An adhesive transdermal patch is applied to the skin and contains medicine that is absorbed into the bloodstream through the skin. It aids in the recovery of an afflicted part of the body. When compared to oral, topical, i. v., and i. m. administration systems, transdermal drug delivery allows a controlled release of the medicine into patients, often by either a porous membrane or by body heat melting small layers of medication embedded in the adhesive. The fundamental drawback of transdermal delivery methods is that the skin is a highly efficient barrier, therefore, only tiny molecules can enter the skin and be administered in this manner.


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