NANOTHERANOSTICS IN CARDIOVASCULAR DISEASES: A NOVEL TOOL

Authors

  • IMRANKHAN NIZAM Department of Pharmaceutics, JSS College of Pharmacy, Ooty, Nilgiris, Tamil Nadu, India https://orcid.org/0000-0003-0483-7927
  • KALAISELVI AASAITHAMBI Divison of Biotechnology, School of Life Sciences (Off Site Campus), JSS Academy of Higher Education and Research, Mysuru, Karnataka, India https://orcid.org/0000-0001-9481-2111
  • ASHA SRINIVASAN Division of Nanoscience and Technology, School of Life Science, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India
  • SARVANA BABU CHIDAMBARAM Department of Pharmacology, JSS College of Pharmacy, Mysore, Karnataka, India
  • PRAVEEN THAGGIKUPPE KRISHNAMURTHY Department of Pharmacology, JSS College of Pharmacy, Ooty, Nilgiris, Tamil Nadu, India
  • SUBBA RAO V. MADHUNAPANTULA Department of Biochemistry, JSS Medical College, Mysore, Karnataka, India https://orcid.org/0000-0001-6050-1323
  • RAJESH THIMMULAPPA Department of Biochemistry, JSS Medical College, Mysore, Karnataka, India
  • GOWTHAMARAJAN KUPPUSAMY Department of Pharmaceutics, JSS College of Pharmacy, Ooty, Nilgiris, Tamil Nadu, India https://orcid.org/0000-0003-0483-7927

DOI:

https://doi.org/10.22159/ijap.2023v15i4.47521

Keywords:

Nanotheranostics, Cardiovascular diseases, Nanocarriers, Imaging

Abstract

The leading cause of mortality worldwide is cardiovascular disease (CVD). Myocardial infarction, ischemic heart disease, ischemic injury, damaged arteries, thrombosis, and atherosclerosis are among the heart and blood vessel issues referred to as CVD. The most prevalent cause of CVD is atherosclerosis, an inflammatory disease of the arterial blood wall. Because of the complexity of CVD, pathophysiology, diagnosis, and therapy remain vital issues. The inadequacies of current treatment and diagnostic methods have given rise to theranostic nanomaterials. "Theranostic nanomaterials" describes a chemical with dual uses, including therapeutic and diagnostic applications. Theranostic nanoparticle imaging contrast can be advantageous for computed tomography (C. T.), positron emission tomography (P. E. T.), and magnetic resonance imaging (M. R. I.).

Additionally, they can cure CVD by employing medication delivery by nanoparticles or photothermal ablation. This study reviews the prevalence of the most recent developments in theranostic nanomaterials for identifying and treating CVD following the order in which diseases advance. Theranostics techniques for CVD detection include M. R. I., CT, near-infrared spectroscopy (NIR), and fluorescence. There have also been discussions of other theranostic nanoparticle-based CVD therapeutic methods.

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Published

07-07-2023

How to Cite

NIZAM, I., AASAITHAMBI, K., SRINIVASAN, A., CHIDAMBARAM, S. B., KRISHNAMURTHY, P. T., MADHUNAPANTULA, S. R. V., THIMMULAPPA, R., & KUPPUSAMY, G. (2023). NANOTHERANOSTICS IN CARDIOVASCULAR DISEASES: A NOVEL TOOL. International Journal of Applied Pharmaceutics, 15(4), 37–42. https://doi.org/10.22159/ijap.2023v15i4.47521

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