OPTIMIZATION OF SUGARCANE (SACCHARUM OFFICINARUM l.) JUICE MICROFILTRATION FOR STORAGE STABILITY AND ANTIHYPERGLYCEMIC ACTIVITY

TETI INDRAWATI; ZAINUR RAHMAN HAKIM; RAHMI HUTABARAT; RATNA DJAMIL; SISTER SIANTURI; MEGAH INDAH DWITA; IMANULLAH

doi:10.22159/ijap.2024.v16s3.06

Authors

TETI INDRAWATI Department of Pharmacy, Faculty of Pharmacy, National Institute of Science and Technology, Moch. Kahfi II St., Bhumi Srengseng Indah No.13, Jagakarsa-12630, South Jakarta, Indonesia https://orcid.org/0000-0002-9741-2006
ZAINUR RAHMAN HAKIM Pharmacognosy and Phytochemistry laboratory, Faculty of Pharmacy, Universitas Pancasila, Srengseng Sawah, Jagakarsa-12640, South Jakarta, Indonesia https://orcid.org/0000-0003-0615-613X
RAHMI HUTABARAT Department of Pharmacy, Faculty of Pharmacy, National Institute of Science and Technology, Moch. Kahfi II St., Bhumi Srengseng Indah No.13, Jagakarsa-12630, South Jakarta, Indonesia
RATNA DJAMIL Pharmacognosy and Phytochemistry laboratory, Faculty of Pharmacy, Universitas Pancasila, Srengseng Sawah, Jagakarsa-12640, South Jakarta, Indonesia https://orcid.org/0009-0005-4045-5258
SISTER SIANTURI Department of Pharmacy, Faculty of Pharmacy, National Institute of Science and Technology, Moch. Kahfi II St., Bhumi Srengseng Indah No.13, Jagakarsa-12630, South Jakarta, Indonesia
MEGAH INDAH DWITA Department of Pharmacy, Faculty of Pharmacy, National Institute of Science and Technology, Moch. Kahfi II St., Bhumi Srengseng Indah No.13, Jagakarsa-12630, South Jakarta, Indonesia
IMANULLAH Department of Pharmacy, Faculty of Pharmacy, National Institute of Science and Technology, Moch. Kahfi II St., Bhumi Srengseng Indah No.13, Jagakarsa-12630, South Jakarta, Indonesia

DOI:

https://doi.org/10.22159/ijap.2024.v16s3.06

Keywords:

Antihyperglycemic, Microfiltration, Saccharum officinarum l., Stability

Abstract

Objective: Sugarcane juice (Saccharum officinarum l.) is a natural source of liquid carbohydrates traditionally used for health and help with diabetes. The content of flavonoids, octacosanol, and saccharic compounds in sugarcane juice is proven to have antihyperglycemic activity, so it is safe to use by diabetics. Unfortunately, sugarcane juice is only stable for 4 h at room temperature. The study aimed to improve sugarcane juice's stability and obtain data on its antihyperglycemic effect.

Methods: This research was conducted by making sugarcane juice, which was then carried out sterilization by microfiltration. The sugarcane juice is then packaged in a special sterile plastic. The results of sugarcane juice storage were then tested for stability at a certain time and antihyperglycemic effectiveness in mice.

Results: The results showed that the stability of sugarcane juice can be extended up to 168 h. Sugarcane juice (Saccharum officinarum l.) at a dose of 5.6 mg/20 g Bodyweight, a dose of 11.2 mg/20 g Bodyweight, and a dose of 16.8 mg/20 g Bodyweight has an antihyperglycemic effect.

Conclusion: Microfiltration techniques can be used to increase the shelf life of sugarcane juice and maintain its qualities as an antihyperglycemic for quite a long time.

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