NANOSUSPENSION: AN OVERVIEW

Smita S. Aher; Sagar T. Malsane; R. B. Saudagar

doi:10.22159/ijcpr.2017.v9i3.19584

Authors

Smita S. Aher Department of Pharmaceutical Chemistry, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik 422213, Maharashtra, India
Sagar T. Malsane Department of Quality Assurance Techniques, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik 422213, Maharashtra, India
R. B. Saudagar Department of Pharmaceutical Chemistry, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik 422213, Maharashtra, India

DOI:

https://doi.org/10.22159/ijcpr.2017.v9i3.19584

Keywords:

Nanosuspension, Solubility enhancement, Particle size, Surfactant, Colloidal dispersion, Oral bioavailability

Abstract

Nanosuspensions are important carriers to develop novel drug formulations. Nanosuspensions have emerged as a promising strategy for the efficient delivery of hydrophobic drugs because of their versatile features and unique advantages. Nanosuspension technology solved the problem of drugs which are poorly aqueous soluble and less bioavailability. Stability and bioavailability of the drugs can be improved by the Nanosuspension technology. Techniques such as media milling and high-pressure homogenization have been used commercially for producing nanosuspensions. Nanosuspensions can be delivered by oral, parenteral, pulmonary and ocular routes. Nanosuspensions can also be used for targeted drug delivery when incorporated in theOcular inserts and mucoadhesive hydrogels. Currently, efforts are being directed to extending their applications in site-specific drug delivery.

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