STUDY OF PREVALENCE OF MULTI-DRUG RESISTANT ACINETOBACTER SPECIES IN VENTILATOR-ASSOCIATED PNEUMONIAE CASES IN A TERTIARY CARE HOSPITAL, VISAKHAPATNAM

MATTAM SUNEETHA RANI; THAMMINA MEHER SRI SAI SUDHA VANI; B. S. G. SAILAJA

doi:10.22159/ijcpr.2024v16i6.5071

Authors

MATTAM SUNEETHA RANI Department of Microbiology, Andhra Medical College, King George Hospital, Visakhapatnam-530002, Andhra Pradesh, India
THAMMINA MEHER SRI SAI SUDHA VANI Department of Microbiology, Andhra Medical College, King George Hospital, Visakhapatnam-530002, Andhra Pradesh, India https://orcid.org/0000-0001-5816-951X
B. S. G. SAILAJA Department of Microbiology, Government Medical College, Madanapalli, Andhra Pradesh, India

DOI:

https://doi.org/10.22159/ijcpr.2024v16i6.5071

Keywords:

Acinetobacter sps, Ventilator associated pneumoniae, Biofilm production, Multidrug resistance, Carbapenems

Abstract

Objective: Acinetobacter sps are important oppurtunistic pathogens with their significance in colonising and persistent biofilm production capabilities. The aim of the present study was to assess the prevalence of multidrug-resistant Acinetobacter sps in ventilator-associated pneumoniae cases in a tertiary care hospital Visakhapatnam.

Methods: A prospective study was conducted on 328 endotracheal aspirate samples received in Clinical Laboratory, Department of Microbiology for a period of 1 y, from June 2023 to June 2024, in mechanical ventilated cases, admitted in intensive care units, in a tertiary care hospital, Visakhapatnam.

Results: Out of 328 samples received, 42 (12.8%) were Acinetobacter isolates with resistance to Aminoglycosides (66.7%), Cephalosporins (57.1%), Quinolones (52.4%), Carbapenems (42.9%). Biofilm production was identified in 31 isolates (73.8%) by Congo Red Agar method in this study.

Conclusion: The potential ability of Acinetobacter sps to form biofilms and antibiotic selective pressure leading to emergence of resistant clones is directly proportional to the injudicious use of antibiotics. There is a strict need of antibiotic stewardship measures in intensive care units to restrict development of pan-resistant strains.

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