• Rajalakshmi P. V. Department of Biochemistry, Biotechnology, and Bioinformatics, Avinashilingam Institute for Home sciences and Higher Education for Women,Coimbatore 641043, TamilNadu, India
  • Kalaiselvi Senthil Department of Biochemistry, Biotechnology, and Bioinformatics, Avinashilingam Institute for Home sciences and Higher Education for Women, Coimbatore 641043, TamilNadu, India


Albizia julibrissin, Antibacterial, Flavonoids


Objective: To test the antibacterial efficacy of leaf, stem, and flower extracts of Albizia julibrissin against bacterial pathogens.

Methods: Extraction of active metabolites was carried out by using six different solvents, and total flavonoid content in each extract was determined by Aluminium chloride method. To determine the antibacterial activity of extracts, disc diffusion method and tube dilution method were carried out. Zone of inhibition and Minimum inhibitory Concentration (MIC) were calculated.

Results: Methanolic extracts of leaf samples of A. julibrissin showed highest extractive value (5.14g/100g) and total flavonoid content (35.14mg/g). In overall leaf extracts of A. julibrissin showed maximum zone of inhibition towards P. vulgaris (10.1 mm*) and least susceptible microorganism is S. typhi (3.5 mm*). Stem and flower extracts inhibited bacterial growth only at higher concentrations (MIC, 160-215 and 65-180µg/ml respectively).

Conclusion: Apart from the energy crop, based on the results and value-added compounds present in A. julibrissin, it may be considered as antibacterial agent in future.


Download data is not yet available.


Vernet G, Mary C, Altmann DM, Doumbo O, Morpeth S, Bhutta ZA, et al. Surveillance for antimicrobial drug resistance in under-resourced countries. Emerg Infect Dis 2014;20(3):434-41.

Glaser R, Becker K, von Eiff C, Meyer-Hoffert U, Harder J. Decreased susceptibility of Staphylococcus aureus small-colony variants toward human antimicrobial peptides. J Invest Dermatol 2014;134(9):2347-50.

Ahmed AS, McGaw LJ, Moodley N, Naidoo V, Eloff JN. Cytotoxic, antimicrobial, antioxidant, antilipoxygenase activities and phenolic composition of Ozoroa and Searsia species (Anacardiaceae) used in South African traditional medicine for treating diarrhoea. S Afr J Bot 2014;95:9-18.

Rijo P, Matias D, Fernandes AS, Simoes MF, Nicolai M, Reis CP. Antimicrobial plant extracts encapsulated into polymeric beads for potential application on the skin. Polymers 2014;6(2):479-90.

Buwa LV, Van Staden J. Antibacterial and antifungal activity of traditional medicinal plants used against venereal diseases in South Africa. J Ethnopharmacol 2006;103(1):139-42.

Babu NP, Pandikumar P, Ignacimuthu S. Anti-inflammatory activity of Albizia lebbeck Benth., an ethnomedicinal plant, in acute and chronic animal models of inflammation. J Ethnopharmacol 2009;125(2):356-60.

Ekenseair AK, Duan L, Carrier DJ, Bransby DI, Clausen EC. Extraction of hyperoside and quercitrin from mimosa (Albizia julibrissin) foliage. Appl Biochem Biotechnol 2006;130(1-3):382-91.

Pitman WD. Establishment and regrowth responses of Albizia julibrissin on Louisiana USA coastal plain soils. Agrofor Syst 2008;74(3):259-66.

Hua H, Feng L, Zhang XP, Zhang LF, Jin J. Anti-angiogenic activity of julibroside J8, a natural product isolated from Albizia julibrissin. Phytomed 2009;16(8):703-11.

Zheng L, Zheng J, Zhao Y, Wang B, Wu L, Liang H. Three anti-tumor saponins from Albizia julibrissin. Bioorg Med Chem Lett 2006;16(10):2765-8.

Roy B, Pramanik K, Mukhopadhyay B. Synthesis of a tetra-and a trisaccharide related to an anti-tumor saponin Julibroside J28†from Albizia julibrissin. Glycoconjugate J 2008;25(2):157-66.

Lau CS, Carrier DJ, Beitle RR, Bransby DI, Howard LR, Lay Jr JO, et al. Identification and quantification of glycoside flavonoids in the energy crop Albizia julibrissin. Bioresour Technol 2007;98(2):429-35.

Yahagi T, Daikonya A, Kitanaka S. Flavonol acylglycosides from flower of Albizia julibrissin and their inhibitory effects on lipid accumulation in 3T3-L1 cells. Chem Pharm Bull 2012;60(1):129-36.

Machado TB, Pinto AV, Pinto MCFR, Leal ICR, Silva MG, Amaral ACF, et al. In vitro activity of Brazilian medicinal plants, naturally occurring naphthoquinones and their analogues, against methicillin-resistant Staphylococcus aureus. Int J Antimicrob Agents 2003;21(3):279-84.

Chang CC, Yang MH, Wen HM, Chern JC. Estimation of total flavonoids content in propolis by two complementary colorimetric methods. J Food Drug Anal 2002;10(3):178-82.

Periyasamy N, Srinivasan M, Balakrishnan S. Antimicrobial activities of the tissue extracts of Babylonia spirata Linnaeus, 1758 (Mollusca: Gastropoda) from Thazhanguda, southeast coast of India. Asian Pac J Trop Biomed 2012;2(1):36-40.

Elizabeth KM. Antimicrobial activity of Terminalia bellerica. Indian J Clin Biochem 2005;20(2):150-3.

Banso A, Adeyemo S. Phytochemical screening and antimicrobial assessment of Abutilon mauritianum, Bacopa monnifera and Datura stramonium. Biokemistri 2006;18(1):39-44.



How to Cite

P. V., R., and K. Senthil. “FLAVONOID CONTENT AND ANTIBACTERIAL ACTIVITY OF ALBIZIA JULIBRISSIN. DURAZZ LEAF, STEM AND FLOWER EXTRACTS AGAINST CLINICALLY ISOLATED BACTERIAL PATHOGENS”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 6, no. 11, Nov. 2014, pp. 506-8, https://journals.innovareacademics.in/index.php/ijpps/article/view/2930.



Short Communication(s)