DRUG UTILIZATION EVALUATION OF ANGIOTENSIN RECEPTOR BLOCKER (ARB) ALONG WITH THEIR ADRS IN A TERTIARY CARE HOSPITAL

Authors

  • MOHAMMAD RIYASAT Department of Pharmacy Practice, College of Pharmacy, Teerthanker Mahaveer University. Delhi Road, NH 24, Bagadpur, Uttar Pradesh 244001, India
  • MD. SHAMIM Department of Pharmacy Practice, College of Pharmacy, Teerthanker Mahaveer University. Delhi Road, NH 24, Bagadpur, Uttar Pradesh 244001, India, Department of Pharmacy, Lakhmi Chand Patwari Pharmacy College, Baghpat. SH 57, Khekra, Uttar Pradesh, 250101, India
  • JIGAR HARIA Department of Medicine, Teerthanker Mahaveer Medical College and Research Centre, Teerthanker Mahaveer University. Delhi Road, NH 24, Bagadpur, Uttar Pradesh 244001, India
  • MOHAMMAD DAUD ALI Department of Pharmacy, Mohammed Al-Mana College for Medical Sciences, Abdulrazaq Bin Hammam Street, Al Safa, Dammam 34222, Saudi Arabia
  • MAHFOOZ HUSSAIN Department of Pharmacy Practice, College of Pharmacy, Teerthanker Mahaveer University. Delhi Road, NH 24, Bagadpur, Uttar Pradesh 244001, India
  • MD. SARFARAZ ALAM Department of Pharmaceutics, College of Pharmacy, Jazan University, Jazan 45142, Saudi Arabia
  • SARFARAZ AHMAD Department of Clinical Pharmacy, College of Pharmacy, Jazan University, Jazan 45142, Saudi Arabia

DOI:

https://doi.org/10.22159/ijpps.2020v12i11.39171

Keywords:

Antihypertensive drugs, Angiotensin Receptor Blockers (ARBs), ADRs, Drug utilization, Telmisartan, Olmesartan, Azilsartan

Abstract

Objective: To evaluate the drug utilization of Angiotensin Receptor Blocker (ARB) along with their ADRs in a tertiary care hospital. And to monitor, report of adverse drug reaction and drug interactions, if any.

Methods: The patients who meet the inclusion and exclusion criteria were enrolled into the study. The pertinent data such as demographic details, drug name, dose, frequency, and laboratory data were gathered from medical records of the patient and results were analyzed.

Results: Total of 100 patients were included in this study, the maximum utilization of antihypertensive drug (ARB) was telmisartan (90%) and widely use of ARBs in the age group of 41-50 y. Total 32 ADRs were observed and most probable ADRs included headache (42.8%), Nausea (14.28%) and dizziness (12.5%).

Conclusion: Telmisartan was the most prescribed and utilized drug than the other drugs of ARBs. Maximum ADRs were noted in females, the most frequent ADRs headache, nausea and dizziness were reported. The majority of reactions were probable on causality assessment done by WHO-UMC and Naranjo’s scale having mild severity. So it can be concluded that considering risk factors, prevention and management of ADRs can drastically improve the therapeutic outcomes of the patients.

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Published

01-11-2020

How to Cite

RIYASAT, M., M. SHAMIM, J. HARIA, M. D. ALI, M. HUSSAIN, M. S. ALAM, and S. AHMAD. “DRUG UTILIZATION EVALUATION OF ANGIOTENSIN RECEPTOR BLOCKER (ARB) ALONG WITH THEIR ADRS IN A TERTIARY CARE HOSPITAL”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 12, no. 11, Nov. 2020, pp. 42-46, doi:10.22159/ijpps.2020v12i11.39171.

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