SYNTHESIS OF COPPER OXIDE NANOPARTICLES USING DESMODIUM GANGETICUM AQUEOUS ROOT EXTRACT
Keywords:
Copper oxide nanoparticles, Desmodium gangeticum, Antioxidant, LLC-PK1 cell lineAbstract
Objective: In this present work, we have synthesized Copper oxide nanoparticles using Desmodium gangeticum root extracts and explored its biological activity.
Methods: The Copper oxide nanoparticles were synthesized by the reduction process. Copper oxide nanoparticles were purified and dried. Scanning electron micrograph analysis showed evenly distributed Copper oxide nanoparticles and was confirmed by UV visible spectroscopy. Characterization of Copper oxide nanoparticles was done with Fourier Transform Infra-Red spectroscopy (FTIR) and Thermo Gravimetric Analysis (TGA). Gram negative and gram positive, bacteria were used to evaluate its antibacterial activity.
Results: Reducing potential and free radical scavenging ability of Copper oxide nanoparticles was measured and found to be high. Indeed, toxicological evaluation in LLC-PK1 cell line suggests that Copper oxide nanoparticles were safer for biomedical applications.
Conclusion: Biologically synthesized copper oxide nanoparticles show significant antioxidant effect and found to be less toxic as compared to the precursor thereby can be used as potential candidate species for various biomedical applications.
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