A STUDY OF PATTERN OF ONYCHOMYCOSIS IN A TERTIARY CARE HOSPITAL OF CENTRAL INDIA
DOI:
https://doi.org/10.22159/ijpps.2022v14i5.44465Keywords:
Onychomycosis, Dermatophytes, KOH wet mount, Fungal cultureAbstract
Objective: This study was undertaken to study the clinico-mycological profile of clinically suspected cases of onychomycosis in the region.
Methods: In this cross-sectional study, 65non-repetitive, clinically diagnosed cases of onychomycosis visiting Dermatology, Venereology and Leprosy OPD of People’s Hospital, Bhopal were included. Nail clippings and scraping beneath the nails were taken from the affected sites. Collected specimens were subjected to standard mycological procedures.
Results: Males were more affected than females. The male to female ratio was 1.4:1. Distal and lateral subungual onychomycosis (DLSO) was the commonest clinical pattern. Out of the total 35 fungal culture isolates, dermatophytes (71.43%) were the most common. Among dermatophytes, Trichophyton rubrum and among non-dermatophytes, Candida spp. was the most common isolate.
Conclusion: Dermatophytes were the most common aetiological agent of onychomycosis in our study with Trichophyton rubrum as the most common isolate. This study also reveals the fact that nowadays, non, dermatophytes are increasingly isolated from cases of onychomycosis.
Downloads
References
Chander J. Textbook of medical mycology. 3rd ed. New Delhi: Mehta Publishers; 2009.
Jain N, Meenakshi Sharma M. Topical application of Eugenia caryophyllus oil against ringworm infection of human beings. Asian J Pharm Clin Res. 2019;12(7):153-7. doi: 10.22159/ajpcr.2019.v12i7.32068.
Sigurgeirsson B, Baran R. The prevalence of onychomycosis in the global population: a literature study. J Eur Acad Dermatol Venereol. 2014;28(11):1480-91. doi: 10.1111/jdv.12323, PMID 24283696.
Gupta AK, Simpson FC. Medical devices for the treatment of onychomycosis. Dermatol Ther. 2012;25(6):574-81. doi: 10.1111/j.1529-8019.2012.01519.x, PMID 23210756.
Shemer A. Update: medical treatment of onychomycosis. Dermatol Ther. 2012;25(6):582-93. doi: 10.1111/j.1529-8019.2012.01551.x, PMID 23210757.
Relloso S, Arechavala A, Guelfand L, Maldonado I, Walker L, Agorio I, Reyes S, Giusiano G, Rojas F, Flores V, Capece P, Posse G, Nicola F, Tutzer S, Bianchi M. Onychomycosis: multicentre epidemiological, clinical and mycological study. Rev Iberoam Micol. 2012;29(3):157-63. doi: 10.1016/j.riam.2011.11.003, PMID 22198612.
Nazar JR, Gerosa PE, Diaz OA. Onychomycoses: epidemiology, causative agents and assessment of diagnostic laboratory methods. Rev Argent Microbiol. 2012;44(1):21-5. doi: 10.1590/S0325-75412012000100005, PMID 22610293.
Piraccini BM, Alessandrini A. Onychomycosis: a review. J Fungi (Basel). 2015;1(1):30-43. doi: 10.3390/jof1010030, PMID 29376897.
Devrari JC, Saxena V, Pai V. A mycological study of clinical samples from suspected mycoses in a tertiary care hospital. Asian J Pharm Clin Res. 2018;11(4):267-70. doi: 10.22159/ajpcr.2018.v11i4.24127.
Adhikari L, Das Gupta AD, Pal R, Singh TS. Clinico-etiologic correlates of onychomycosis in sikkim. Indian J Pathol Microbiol. 2009;52(2):194-7. doi: 10.4103/0377-4929.48915, PMID 19332910.
Vinod S, Grover S, Dash K, Singh G. A clinico-mycological evaluation of onychomycosis. Indian J Dermatol Venereol Leprol. 2000;66(5):238-40. PMID 20877087.
Grover S. Clinico mycological evaluation of onychomycosis at Banglore and Jorhat. Indian J Dermatol Venerol Leprol. 2003;69:284-6.
Jesudanam TM, Rao GR, Lakshmi DJ, Kumari GR. Onychomycosis: a significant medical problem. Indian J Dermatol Venereol Leprol. 2002;68(6):326-9. PMID 17656990.
Veer P, Patwardhan NS, Damle AS. Study of onychomycosis: prevailing fungi and pattern of infection. Indian J Med Microbiol. 2007;25(1):53-6. doi: 10.4103/0255-0857.31063, PMID 17377354.
HPN, NP, BP. Study of onychomycosis at a tertiary care hospital in south India. JEMDS. 2012;1(5):823-9. doi: 10.14260/jemds/132.
Beena SS, Bhavana MV, Babu PRS. Onychomycosis: prevalence and its etiology in a tertiary care hospital, South India. Int J Health Sci Res. 2013;3(10):81-5.
Lone R. A study on clinico-mycological profile, aetiological agents and diagnosis of onychomycosis at a government medical college hospital in Kashmir. J Clin Diagn Res. 2013;7(9):1983-5. doi: 10.7860/JCDR/2013/5969.3378.
Vijaya D, Anandkumar BH, Geetha SH. Study of onychomycosis. Indian J Dermatol Venereol Leprol. 2004;70(3):185-6. PMID 17642607.
Gupta M, Sharma NL, Kanga AK, Mahajan VK, Tegta GR. Onychomycosis: clinico-mycologic study of 130 patients from Himachal Pradesh, India. Indian J Dermatol Venereol Leprol. 2007;73(6):389-92. doi: 10.4103/0378-6323.37055, PMID 18032856.
Published
How to Cite
Issue
Section
Copyright (c) 2022 GAURAV SAXENA, KALPANA SADAWARTE, MOHIT KULMI, ABHISHEK MEHTA
This work is licensed under a Creative Commons Attribution 4.0 International License.
