NEUROTOX: A UNIQUE DATABASE FOR ANIMAL NEUROTOXINS
Keywords:
Neurotoxins, Biological databases, Protein modeling, RDBMS, Toxin databasesAbstract
Objective: A wide range of toxic effects against other species are affected through potential protein molecules called neurotoxins. Among various kinds of toxins, neurotoxins play a critical role in life of other organisms (especially humans). So it is relatively important to know more about neurotoxins and their action on biological systems. All around the world several research works are progressing in the area of neurotoxins.
Methods: Here we present NEUROTOX, a database which contains more than 1400 toxin entries originating from more than ~248 different species. The data was enriched with the related data derived from various other protein sequence as well as structural databases and several literature resources. Each entry of toxin contains 18 fields providing detailed information on neurotoxins and their source, fasta formatted protein sequences, molecular weight, toxicity information along with their literature references.
Results: In addition, 1086 computationally resolved 3D structures of toxin proteins with validation results were made available for download.
Conclusion: The easy to use and freely accessible NEUROTOX database is available online at http: //www. neuro-tox. org and it provides the large range data on toxins.
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