FREE RADICAL SCAVENGING AND ANTIOXIDANT PROPERTIES OF MARINE RED ALGAE HYPNEA MUSCIFORMIS

Authors

  • Pandian A. Department of Biochemistry and Biotechnology, Annamalai University, Annamalai Nagar, Tamil Nadu, India
  • Baskaran K. Department of Biochemistry and Biotechnology, Annamalai University, Annamalai Nagar, Tamil Nadu, India
  • Suba Shini Assistant Professor Department of Biochemistry and Biotechnology, Annamalai University

Keywords:

Hypnea musciformis, Free radical scavenging, Antioxidant activity

Abstract

Objective: The study focused on determining the antioxidant properties of the Hypnea musciformis methanol crude extracts, from the red algae.

Methods: The evaluation of antioxidant properties was determined by 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2'-azinobis 3ethylbenzthiazoline-6-sulphonic acid (ABTS), ferric reducing antioxidant power (FRAP), nitric oxide scavenging assay (NO), reducing power, superoxide radical scavenging (SOD), hydroxyl and hydrogen peroxide radical assay, the metal chelating activity as well as phosphomolypdenum assay.

Results: Among the tested red algae, the maximum antioxidant activity was recorded in the methanol extract of Hypnea musciformis. Whereas methanolic crude extract of red algae and diatom showed good antioxidant potential.

Conclusion: This study suggests that methanolic crude extracts contain different potential antioxidant compounds capable to scavenge different types of free radicals.

 

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Author Biography

Suba Shini, Assistant Professor Department of Biochemistry and Biotechnology, Annamalai University

Assistant Professor
Department of Biochemistry and Biotechnology,
Annamalai University

References

Sachindra NM, Airanthi MK, Hosokawa M, Miyashita K. Radical scavenging and singlet oxygen, quenching activity of extracts from Indian seaweeds. J Food Sci Technol 2009;47(1):94-9.

Vijayavel K, Martinez JA. In vitro antioxidant and antimicrobial activities of two hawaiian marine limu: Ulva fasciata (Chlorophyta) and Gracilaria salicornia (Rhodophyta). J Med Food 2010;13(6):1494-9.

Kumar M, Kumari P, Trivedi N, Shukla MK, Gupta V, Reddy CRK, et al. Minerals, PUFAs and antioxidant properties of some tropical seaweeds from Saurashtra coast of India. J Appl Physiol 2011;23:797-810.

Dawczynski C, Schubert R, Jahreis G. Amino acids, fatty acids, and dietary fiber in edible seaweed products. Food Chem 2007;103(3):891–9.

Gupta S, Abu-Ghannam N. Recent developments in the application of seaweeds or seaweed extracts as a means for enhancing the safety and quality attributes of foods. Innovative Food Sci Emerging Technol 2011;12:600–9.

Kuda T, Tsunekawa M, Goto H, Araki Y. Antioxidant properties of four edible algae harvested in the Noto Peninsula, Japan. J Food Compos Anal 2005;18:625-33.

Yuan YV, Walsh NA. Antioxidant and antiproliferative activities of extracts from a variety of edible seaweeds. Food Chem Toxicol 2006;44:1144-50.

Al-Amoudi OA, Mutawie HH, Patel AV, Blunden G. Chemical composition and antioxidant activities of Jeddah cornice algae. Saudi J Biol Sci 2009;16:23–9.

Hay-Memon A, Shameel M. A taxonomic study of some red algae commonly growing on the coast of Karachi. Pak J Mar Sci 1996;5:113-37.

Nizmuddin M, Campbell AC. Glossophorella, a new genus of the family Dictyotaceae (Dictyotalesphaeophyta) and its ecology from the coast of the sultanate of oman. Pak J Bot 1995;27:257-62.

Samuel M, Shaikh W, Khan R. Comparative fatty acid composition of five species of Dictyota (Phaeophyta). Botanical Marina 1991;34:425-8.

Melo VMM, Medeiros DA, Rios FJB, Castelar LIM, Carvalho AD. Antifungal properties of proteins (agglutinins) from the red alga Hypnea musciformis (Wulfen) Lamouroux. Botanica Marina 1997;40(4):281-4.

Salimabi, Das B. Antispasmodic and antiinflammatory activity of carrageenan from Hypnea musciformis Wulfen, Indian J Pharmacol 1980;12(4):259-61

Rabia Alghazeer, Fauzi Whida, Entesar Abduelrhman, Fatiem Gammoudi, Salah Azwai. Screening of antibacterial activity in marine green, red and brown macroalgae from the western coast of Libya. Nat Sci 2013;5(1):7-14.

Ozgur Vatan, Serap Celikler, Gamze Yildiz. In vitro antigenotoxic and anti-oxidative capacity of Hypnea musciformis (Wulfen) Lamouroux extract in human lymphocytes. Afr J Biotechnol 2011;10(4):484-90.

Arcisio Vieira de Britoa, Rafael da Silva Prudêncioa, Adriano Bezerra Salesa. Anti inflammatory effect of a sulfated polysaccharide fraction extracted from the red algae Hypnea musciformis via the suppression of neutrophil migration by the nitric oxide signalling pathway. J Pharm Pharmacol 2012;19(1):120-8.

Subhashini N, Nagarajan G, Kavimani S. In vitro antioxidant and anticholinesterase activities of Garcinia combogia. Int J Pharm Pharm Sci 2011;3:129-32.

Huang MH, Huang SS, Wang BS. Antioxidant and anti-inflammatory properties of Cardiospermum halicacabum and its reference compounds ex vivo and in vivo. J Ethnopharmacol 2011;133:743-50.

Xu W, Zhang F, Luo Y, Ma L, Kou X, Huang K. The antioxidant activity of a water-soluble polysaccharide purified from Pteridium aquilinum. Carbohydr Res 2009;344:217-22.

Sakat SS, Juvekar AR, Gambhire MN. In vitro antioxidant and anti-inflammatory activity of methanol extract of Oxalis corniculata Linn. Int J Pharm Pharm Sci 2010;2:146-55.

Yen GC, Chen HY. Antioxidant activity of various tea extracts in relation to theirantimutagenicity. J Agric Food Chem 1995;43:27–32.

Naskar S, Islam A, Mazumder UK. In vitro and in vivo antioxidant potential of Hydromethanolic extract of phoenix dactylifera fruits. J Sci Res 2010;2:144-57.

Chou HG, Kuo JT, Lin ES. Comparative antioxidant properties of water extracts fromDifferent parts of Beefsteak plant (Perilla frutescens). J Food Drug Anal 2009;17:489-96.

Delpour AA, Ebrahimzadeh MA, Nabawi SF, Nabavi SM. Antioxidant activity of the Methanol extract of Ferula asafetida and its essential oil composition. Grassy Aceites 2009;60:405-12.

Smirnoff N, Cumbes QJ. Hydroxyl radical scavenging activity of compatible solutes. Phytochem 1989;28:1057-60.

Sahaa MR, Hasana SMR, Aktera R, Hossaina MM, Alamb MS, Alam MA, Mazumder MEH. In vitro free radical scavenging activity of methanol extract of the leaves of Mimusopselengi Linn. Bangladesh J Vet Med 2008;6(2):197–202.

Cotelle N, Bemier JL, Catteau JP, Pommery J, Wallet JC, Gaydou EM. Antioxidant properties of hydroxyl-flavones. Free Radical Biol MED 1996;20;35–43.

Roginsky V, Lissi EA. Review of methods to determine the chain breaking antioxidant activity in food. Food Chem 2005;92:235–54.

Vinayak RC, Sudha SA, Chatterji A. Bioscreening of a few green seaweeds from India for their cytotoxic and antioxidant potential. J Sci Food Agric 2011;91:2471-6.

Matanjun P, Mohamed S, Mustapha NM, Muhammad K, Ming CH. Antioxidant activities and phenolic content of eight species of seaweed from North Borneo. J Appl Phycol 2008;20:367-73.

Yen GC, Chen HY. Antioxidant activity of various tea extracts in relation to their antimutagenicity. J Agric Food Chem 1995;43:27-32.

Sanja SD, Sheth NR, Patel NK, Dhaval Patel, Biraju Patel. Characterization and evaluation of antioxidant activity of Portulaca oleracea. Int J Pharm Pharm Sci 2009;1(1):74-84.

Nakayama R, Tamura Y, Kikuzaki H, Nakatani N. Antioxidant effect of the constituents of susabinori (Porphyra yezoensis). J Am Oil Chem Soc 1999;76:649–53.

Rashmi C, Vinayak Sabu AS, Anil Chatterji. Bio prospecting of a little brown seaweeds for their cytotoxic and antioxidant activities 2010; doi: 10.1093/ecam/neq024. [Article in Press].

Srikanth G, Babu SM, Kavitha CHN, Roa MEB, Vijaykumar N, Pradeep CH. Studies on in-vitro antioxidant activities of Carica papaya aqueous leaf extract. Res J Pharm Biol Chem Sci 2010;1:59-65.

Krishnan Bakaran, Kodukkur Viswanathan Pugalendi, Ramalingam Saravanan. Free radical scavenging activity of ethyl acetate extract of Cardiospermum halicacabum by In vitro assays. AJBPR 2014;2:300-8.

Subashini R, Prasanth R. Studies of free radicals scavenging potential of seaweed Enteromorpha sp. Chem Sci Rev Lett 2014;3(12):931-40.

Srikanth G, Babu SM, Kavitha CHN, Roa MEB, Vijaykumar N, Pradeep CH. Studies on in-vitro antioxidant activities of Carica papaya aqueous leaf extract. Res J Pharm Biol Chem Sci 2010;1:59-65.

Siriwardhana N, Lee KW, Kim SH, Ha JW, Jeon YJ. Antioxidant activity of Hizikia fusiformis on reactive oxygen species scavenging and lipid peroxidation inhibition. Food Sci Tech Int 2003;9(5):339–46.

Wang T, Jónsdóttir R, Ólafsdóttir G. Total phenolic compounds, radical scavenging and metal chelation of extracts from Icelandic seaweeds. Food Chem 2009;116:240–8.

Zheng GO, Kenney PM, Lam LK. Anethofuran, carvone and limonene: potential chemopreventive agents from dill weed oil and caraway oil. Plants Medica1992;58:338-41.

Published

01-08-2015

How to Cite

A., P., B. K., and S. Shini. “FREE RADICAL SCAVENGING AND ANTIOXIDANT PROPERTIES OF MARINE RED ALGAE HYPNEA MUSCIFORMIS”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 8, no. 8, Aug. 2015, pp. 227-31, https://journals.innovareacademics.in/index.php/ijpps/article/view/5863.

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