• Qhuddsia Q. N. Associate Professor, Dept. of Amraze Niswan wa Ilmul Qabalat, Govt. Nizamia Tibbi College
  • Arshiya Sultana Lecturer, Dept. of Amraze Niswan wa Qabalat, National Institute of Unani Medicine, PG Institute of Research, Bangalore, Karnataka
  • Iftekhar Jahan Emeritus Professor, Dept. of Amraze Niswan wa Ilmul Qabalat, Govt. Nizamia Tibbi College, Hyderabad, Telangana


Abnormal vaginal discharge, Endocervicitis, Randomized trial, Unani formulation


Objective: To compare the efficacy of Unani formulation in chronic endocervicitis.

Methods: A parallel, comparative randomized trial was conducted at Govt. Nizamia General Hospital, Hyderabad from 1998 to 2000 in 50 patients (25 in each group) with sign and symptoms of endocervicitis. The intervention was administered per oral and locally for 10 d from day 7 to day 16 of each menstrual cycle up to three consecutive months in both groups (A and B). Group A received 10 g powder of mako khusk, chobchini, and gul surkh with equal quantity of sugar orally, twice daily and locally douching with 100 ml of joshandae of barge neem (5g), and gule tesu (5g) was done per vaginum followed by insertion of humool (pessary) of loabe khatmi (5g), and safoof sadberg (3) mixed with roghan neem (10 ml). Group B received 7.5 g powder of ushba and kasni mixed with equal quantity of sugar orally, twice daily. Humool of loabe hulba (5g), and raswat (3g) with roghane gul was kept per vaginum. The outcome was inter-group comparison of effectiveness of Unani medicine by observing change in subjective and objective parameters of endocervicitis. Chi-square/Fisher Exact tests were carried out to observe the inter group comparison.

Results: The demographic characteristics were statistically not significant (P>0.05) between the groups. No statistical difference was noted in the subjective and objective parameters of endocervicitis (P>0.05), showing that both groups were comparable.

Conclusion: Group A and B were comparable in ameliorating sign and symptoms of endocervicitis because of anti-inflammatory, analgesic and anti-microbial effects. Further, randomized controlled trials are recommended.


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Tirumalasetti N, Navyaa VR. Utility of pap smear study in the diagnosis of various neoplastic and non neoplastic lesions of cervix. Int J Pharm Res Bio-Sci 2012;1:379-89.

Shalini S, Murthy NS, Shalini CN, Rajanna MS, Geethamani V. Study of reproductive tract infections among women attending urban health centers in Bangalore city. Indian J Prev Soc Med 2011;42:267-72.

http://www.cdc.gov/std/stats10/trends.htm. [Last accessed on 2012 Oct 24]

Dutta DC. Text book of Gynaecology. 3rd ed. Calcutta: New Central Book Agency (P) Ltd; 2001.

Marrazzo JM, Martin DH. Management of women with Cervicitis. Clin Infect Dis 2007;44(Suppl 3):S102-10.

Kumar P, Malhotra N. Jefffcoate‘s Principles of Gynaecolgy. 7th ed. New Delhi: Jaypee Brothers Medical Publishers (P) Ltd; 2008.

Mukherjee GG, Chakravarty S, Pal B, Mukherjee B. Current Obstetrics and Gynaecology. 1st ed. New Delhi: Jaypee Brothers Medical Publishers (P) Ltd; 2007.

Sina I. Al Qanoon Fit Tib. (Urdu trans: Kantoori GH). New Delhi: Idarae Kitabus Shifa; 2010.

Razi ABZ. Al Hawi Fil Tib. Vol IX. New Delhi: Central Council Research in Unani Medicine; 2001.

Ghani N. Khazainul Advia. New Delhi: Idarae Kitabus Shifa; 2001.

Nadkarni AK. Indian Materia Medica. Vol. II. Mumbai: Popular Prakashan; 2009.

Kabiruddin M. Makhzanul Mufredat. New Delhi: Eijaz Publishing House; 2002.

Kaushik D, Jogpal V, Kaushik P, Lal S, Saneja A, Sharma C, et al. Evaluation of activities of Solanum nigrum fruit extract. Arch Appl Sci Res 2009;1:43-50.

Chuan-li Lu, Wei Zhu, Min Wang, Xiao-jie Xu, Chuan-jian Lu. Antioxidant and anti-inflammatory activities of phenolic-enriched extracts of Smilax glabra. J. Evidence-Based Complementary Altern Med 2014. doi: 10.1155/2014/910438. [Article in Press]

Hajhashemi V, Ghannadi A, Hajiloo M. Analgesic and anti-inflammatory effects of Rosa damascena Hydroalcoholic extract and its essential oil in animal Models. Iran J Pharm Res 2010;9:163-8.

Boskabady MH, Shafei MN, Saberi Z, Amini S. Pharmacological effects of Rosa Damascena. Iran J Basic Med Sci 2011;14:295-307.

Azam MM, Mamun-Or-Rashid ANM, Towfique NM, Sen MK, Nasrin S. Pharmacological potentials of Melia Azedarach L.-A review. Am J Bio Sci 2013;1:44-9.

Pal P, Bose S. Phytopharmacological and Phytochemical review of Butea monosperma. Int J Res Pharm Biomed Sci 2011;2:1374-88.

Arora D, Rani A, Sharma A. A review on phytochemistry and ethnopharmacological aspects of genus Calendula. Pharmacogn Rev 2013;7:179-87.

Ammar M, Alokbi Y, Mohammed A. Study of anti-inflammatory effect of some medicinal edible plants growing in Egypt. J Islamic Acad Sci 1997;10:113-22.

Panchal GA, Panchal SJ, Patel JA. Hemidesmus indicus: a review. Pharmacologyonline 2009;2:758-71.

Javadzadeh SM, Ebrahimi A. The traditional uses and pharmacological effects of different parts Berberis vulgaris (berberine). Iran Sci Agric 2013;1:61-6.



How to Cite

N., Q. Q., A. Sultana, and I. Jahan. “EFFICACY OF UNANI FORMULATIONS IN CHRONIC ENDOCERVICITIS: A RANDOMIZED COMPARATIVE STUDY”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 7, no. 11, Nov. 2015, pp. 101-4, https://journals.innovareacademics.in/index.php/ijpps/article/view/8416.



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