ROLE OF PHARMACISTS IN REDUCING DRUG-RELATED PROBLEMS IN HEMODIALYSIS OUTPATIENTS

Authors

  • Romauli Lumbantobing Department of Pharmacy, Universitas Kristen Indonesia Hospital, Jakarta, Indonesia
  • Rani Sauriasari Department of , Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia.
  • Retnosari Andrajati Department of , Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia.

DOI:

https://doi.org/10.22159/ajpcr.2017.v10s5.23110

Keywords:

Role of pharmacists, Drug-related problems, PCNE-602, Hemodialysis, Outpatient

Abstract

 

 Objectives: Hemodialysis outpatients have a higher risk of developing drug-related problems. Pharmacists play a key role in identifying and preventing these drug-related problems. This study aimed to assess the effect of pharmacist intervention on the number and types of drug-related problems in outpatients undergoing hemodialysis at Indonesia Christian University Hospital.

Methods: This pre- and post-prospective study was conducted from January 2013 to June 2013. We evaluated 86 patients who were prescribed 804 drugs.

Results: A total of 337 drug-related problems were identified (41.86% of the total drugs prescribed). The types of drug-related problems identified were as follows: Failed therapy (18.69%); sub-optimal therapy (52.23%); indication of non-administration of therapy (2.37%); and non-allergic adverse drug effects (26.71%). The physicians received 59 recommendations, and the patients received 278 recommendations. These recommendations resulted in a decrease in ineffective drug therapy or therapeutic failure (18.69-0%), sub-optimal therapy (52.23-21.36%), indications of non-administration of drug (2.37-2.08%), and non-allergic adverse drug effects (26.71-9.20%). The factors that significantly affected the occurrence of drug-related problems were hemodialysis frequency, number of comorbidities, and number of drugs prescribed. Patients undergoing hemodialysis 3 times a week were more likely to experience a decrease in drug-related problems than those undergoing hemodialysis twice a week (odds ratio 26.33, 95% confidence interval 2.710-255.884).

Conclusions: Pharmacist intervention could decrease drug-related problems in hemodialysis patients.

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References

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Published

01-10-2017

How to Cite

Lumbantobing, R., R. Sauriasari, and R. Andrajati. “ROLE OF PHARMACISTS IN REDUCING DRUG-RELATED PROBLEMS IN HEMODIALYSIS OUTPATIENTS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 10, no. 17, Oct. 2017, pp. 108-13, doi:10.22159/ajpcr.2017.v10s5.23110.

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