EFFECT OF SLEEP DEPRIVATION ON REMINISCENCE AND APPREHENSION BEHAVIOR IN WISTAR ALBINO RATS

KEERTHI PRIYA CS; MALATHI S; RAVINDRAN RAJAN

doi:10.22159/ajpcr.2020.v13i1.35187

Authors

KEERTHI PRIYA CS Department of Physiology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Chennai, Tamil Nadu, India.
MALATHI S Department of Physiology, Madha Medical College and Hospital, Kovur, Thandalam, Chennai, Tamil Nadu, India. https://orcid.org/0000-0001-7769-3624
RAVINDRAN RAJAN Department of Physiology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Chennai, Tamil Nadu, India.

DOI:

https://doi.org/10.22159/ajpcr.2020.v13i1.35187

Keywords:

Behavior, Sleep deprivation, Cognition

Abstract

Objective: The aim of the present study is to investigate the effect of paradoxical sleep deprivation (SD) on learning and memory impairment and anxiety-like behavior in female Wistar albino rats.

Methods: Eight-arm radial maze, open-field test, and light and dark test were used to assess the animals learning and memory and anxiety-like behavior.

Results: SD associated with weaker learning and memory and increased anxiety- and depressive-like behavior in animals.

Conclusion: Animals were exposed to SD showed learning and memory impairment and also exhibited increased anxiety- and depressive-like behavior when compared to control animals.

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