LARVICIDAL POTENTIAL OF INDIGOFERA TINCTORIA (FABACEAE) ON DENGUE VECTOR (AEDES AEGYPTI) AND ITS ANTIMICROBIAL ACTIVITY AGAINST CLINICAL ISOLATES

Authors

  • Sakthivel Srinivasan Ph.D Student, Department of Physiology, Dr ALM PGIBMS, University of Madras, Taramani,Chennai-113, India.
  • Wankupar Wankhar Ph.D Student, Department of Physiology, Dr ALM PGIBMS, University of Madras, Taramani,Chennai-113, India.
  • Sheeladevi Rathinasamy Associate Professor and Head, Department of Physiology, Dr ALM PGIBMS, University of Madras, Taramani,Chennai-113, India.
  • Ravindran Rajan Assistant Professor, Department of Physiology, Dr ALM PG IBMS, University of Madras, Taramani,Cennai-113, India.

Abstract

 

antimicrobial efficacy against clinical isolates.
Methods: The extract was tested at various concentrations 64, 128, 256, and 512 mg/ml for antimicrobial activity and 0.1 and 5 mg/L were prepared
for larvicidal activity. The numbers of dead larvae were counted after 24 hrs of exposure.
Result: The lowest minimum inhibitory concentration (MIC) values of the extract were 128 mg/ml against Klebsiella spp. - 1 alone and rest of the
clinical test pathogens execute MIC activity at 512 mg/ml. The extract also showed antifungal activity with MIC of 64 mg/ml against the Candida
albicans. Larvicidal activity of I. tinctoria extract were tested against fourth instar larvae A. aegypti and larval mortality were found after 24 hrs with
lethal concentration (LC50)=3.1870 and LC90=5.3991 were observed.
Conclusions: These results indicated that the extract displayed larvicidal potential on A. aegypti and antimicrobial activity against clinical isolates.

Keywords: Infectious disease, Indigofera tinctoria, Antimicrobial activity, Larvicidal activity.

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Published

01-05-2015

How to Cite

Srinivasan, S., W. Wankhar, S. Rathinasamy, and R. Rajan. “LARVICIDAL POTENTIAL OF INDIGOFERA TINCTORIA (FABACEAE) ON DENGUE VECTOR (AEDES AEGYPTI) AND ITS ANTIMICROBIAL ACTIVITY AGAINST CLINICAL ISOLATES”. Asian Journal of Pharmaceutical and Clinical Research, vol. 8, no. 3, May 2015, pp. 316-9, https://journals.innovareacademics.in/index.php/ajpcr/article/view/5780.

Issue

Vol 8 Issue 3 (May - June) 2015

Section

Original Article(s)

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