• ASHISH SHARMA Department of Pharmacology, Adesh Medical College and Hospital, Shahbad, Haryana, India.
  • ARNAV SHARMA Department of Psychiatry, LHMC and Associated Hospitals, New Delhi, India.




Curcuma longa, Aqueous extract, Motor performance


Objective: This study was performed to see the effects of aqueous extract of purified Curcuma longa (CL) on motor performance of albino mice using rota test.

Methods: CL at 50mg/kg body weight (b.w.) (CL50), CL at 100 mg/kg b.w. (CL100), and CL at 200 mg/kg b.w. (CL200) with negative and positive controls were used. The experimental results were represented as mean±2 standard deviation, p was set at < 0.05. Statistical differences between the test drug and control groups as well as within the test drug groups were calculated using Mann–Whitney U-test.

Results: As compared to CL200, DW (distilled water 10 ml/kg p.o.) group fall off time was significantly less (p=0.004). Diazepam (5 mg/kg i.p.) group stayed for lesser time on the rotating rod than CL50, CL100, and CL200 groups (p=0.004). Fall off time in CL100 group was significantly lesser than CL 200 group (p=0.019).

Conclusion: This study showed that CL possesses motor performance increasing effects at 200 mg.


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How to Cite

SHARMA, A., and A. SHARMA. “EFFECTS OF AQUEOUS EXTRACT OF PURIFIED CURCUMA LONGA ON MOTOR PERFORMANCE IN MICE”. Asian Journal of Pharmaceutical and Clinical Research, vol. 16, no. 4, Apr. 2023, pp. 142-4, doi:10.22159/ajpcr.2023.v16i4.45731.



Original Article(s)