A STUDY OF OCCURRENCE OF ANTIBIOTIC RESISTANCE REPORTED AGAINST STAPHYLOCOCCUS AUREUS IN THE DEPARTMENT OF MICROBIOLOGY IN A TERTIARY CARE HOSPITAL IN HAPUR
DOI:
https://doi.org/10.22159/ajpcr.2023.v16i12.48314Keywords:
Antibiotics, Resistance, Staphylococcus aureusAbstract
Objective: The aim of the study is to evaluate the occurrence of antibiotic resistance reported against Staphylococcus aureus in the department of microbiology in a tertiary care hospital in Hapur.
Methods: Urine, pus, blood, throat swab, and sputum samples of 15–60-year-old patients were collected and cultured. 100 samples were selected where S. aureus had grown. Bacteria were identified and the antimicrobial sensitivity testing was carried out.
Results: The strain of resistant bacteria originates from an environment where several antibiotics are used. The bacteria were seen to be resistant frequently to 2–5 antibiotics. This indicates earlier exposure of the isolated bacteria to these drugs.
Conclusion: The high multiple antibiotic resistance is identified in this study and it is necessary to make changes to national antibiotic policy.
Downloads
References
Tan SY, Tatsumura Y, Fleming A. Alexander Fleming (1881-1955): Discoverer of penicillin. Singapore Med J 2015;56:366-7. doi: 10.11622/smedj.2015105, PMID 26243971
Science History Institute, Fleming A. 2017. Available from: https:// www.sciencehistory.org/historical-profile/alexander-fleming [Last accessed on 2020 Apr 27].
Denny DC, Karan S. Antibiotic resistance (ABR) and community pharmacist: A review. Asian J Pharm Clin Res 2021;14:37-9. doi: 10.22159/ajpcr.2021.v14i9.42018
Ansari M. Evaluation of community pharmacies regarding dispensing practices of antibiotics in two districts of central Nepal. PLoS One 2017;12:e0183907. doi: 10.1371/journal.pone.0183907
Zahreddine L, Hallit S, Shakaroun S, Al-Hajje A, Awada S, Lahoud N. Knowledge of pharmacists and parents towards antibiotic use in pediatrics: A cross-sectional study in Lebanon. Pharm Pract (Granada) 2018;16:1194. doi: 10.18549/PharmPract.2018.03.1194
Fymat AL. Antibiotics and antibiotic resistance. Biomed J Sci Tech Res 2017;1:65-80. doi: 10.26717/BJSTR.2017.01.000117
Addis M. A review on antibiotic resistant and implication on food chain. Food Sci Qual Manag 2015;42:29-40.
Shrestha LB, Bhattarai NR, Khanal B. Antibiotic resistance and biofilm formation among coagulase-negative staphylococci isolated from clinical samples at a tertiary care hospital of Eastern Nepal. Antimicrob Resist Infect Control 2017;6:89. doi: 10.1186/s13756-017-0251-7, PMID 28883911
Hadi MA, Karami NA, Al-Muwalid AS, Al-Otabi A, Al-Subahi E, Bamomen A, et al. Community pharmacists’ knowledge, attitude, and practices towards dispensing antibiotics without prescription (DAwP): A cross-sectional survey in Makkah Province, Saudi Arabia. Int J Infect Dis 2016;47:95-100. doi: 10.1016/j.ijid.2016.06.003, PMID 27343987
Poyongo BP, Sangeda RZ. Pharmacists’ knowledge, attitude and practice regarding the dispensing of antibiotics without prescription in Tanzania: An explorative cross-sectional study. Pharmacy (Basel) 2020;8:238. doi: 10.3390/pharmacy8040238, PMID 33322193
Fischbach MA, Walsh CT. Antibiotics for emerging pathogens. Science 2009;325:1089-93. doi: 10.1126/science.1176667, PMID 19713519
Davies J, Davies D. Origins and evolution of antibiotic resistance. Microbiol Mol Biol Rev 2010;74:417-33. doi: 10.1128/MMBR.00016- 10, PMID 20805405
Khan FU, Khan FU, Hayat K, Ahmad T, Khan A, Chang J, et al. Knowledge, attitude, and practice on antibiotics and its resistance: A two-phase mixed-methods online study among Pakistani community pharmacists to promote rational antibiotic use. Int J Environ Res Public Health 2021;18:1320. doi: 10.3390/ijerph18031320, PMID 33535695
Sakeena MH, Bennett AA, McLachlan AJ. Enhancing pharmacists’ role in developing countries to overcome the challenge of antimicrobial resistance: A narrative review. Antimicrob Resist Infect Control 2018;7:63. doi: 10.1186/s13756-018-0351-z, PMID 29744044
McCullough AR, Parekh S, Rathbone J, Del Mar CB, Hoffmann TC. A systematic review of the public’s knowledge and beliefs about antibiotic resistance. J Antimicrob Chemother 2016;71:27-33. doi: 10.1093/jac/dkv310, PMID 26459555
Muloi D, Fèvre EM, Bettridge J, Rono R, Ong’are D, Hassell JM, et al. A cross-sectional survey of practices and knowledge among antibiotic retailers in Nairobi, Kenya. J Glob Health 2019;9:010412. doi: 10.7189/ jogh.09.020412, PMID 31489183
Peterson GM, Wu MS, Bergin JK. Pharmacist’s attitudes towards dispensing errors: Their causes and prevention. J Clin Pharm Ther 1999;24:57-71. doi: 10.1046/j.1365-2710.1999.00199.x, PMID 10319909
Published
How to Cite
Issue
Section
Copyright (c) 2023 Shipra Kaushik
This work is licensed under a Creative Commons Attribution 4.0 International License.
The publication is licensed under CC By and is open access. Copyright is with author and allowed to retain publishing rights without restrictions.
