ISCHEMIA-MODIFIED ALBUMIN AND THYROID HORMONE LEVELS IN FIRST-TRIMESTER ABORTIONS: A RELATIONSHIP?

Amit R Barapatre; Pallavi Anil rathod; VENKATESH RATHOD; Avinash Namdeo Jadhao

doi:10.22159/ajpcr.2023.v16i12.48413

Authors

Amit R Barapatre Department of Biochemistry, TNMC and BYL Nair Charitable Hospital, Mumbai, Maharashtra, India. https://orcid.org/0009-0000-3739-382X
Pallavi Anil rathod Department of Obstetrics and Gynaecology, Kasturba Hospital for Infectious Diseases, Mumbai, Maharashtra, India.
VENKATESH RATHOD Department of Physiology, Seth GSMC and KEMH Parel, Mumbai, Maharashtra, India.
Avinash Namdeo Jadhao Department of Biochemistry, Seth GSMC and KEMH Parel, Mumbai, Maharashtra, India. https://orcid.org/0000-0002-7736-7615

DOI:

https://doi.org/10.22159/ajpcr.2023.v16i12.48413

Keywords:

Abortion, IMA, Thyroid profile

Abstract

Objectives: The objectives are to estimate maternal thyroid hormone levels and ischemia-modified albumin (IMA) levels in first-trimester pregnancy loss and to study the correlation between the maternal thyroid hormone levels and the IMA.

Patients and Methods: We recruited 45 pregnant women with recurrent pregnancy loss (RPL) from our obstetric clinic as cases and 45 healthy pregnant women with the same gestational age and successful pregnancy outcomes as controls.

Results: There is no correlation between the maternal thyroid hormone levels and the IMA levels in first-trimester pregnancy loss. Maternal IMA levels appear to be elevated in women with early RPL.

Conclusion: In cases of first-trimester pregnancy loss, there is no association between maternal thyroid hormone levels and IMA levels. IMA cannot be used for the diagnosis and follow-up of early RPL because maternal IMA levels appear to be higher in women with early RPL.

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Author Biographies

Amit R Barapatre, Department of Biochemistry, TNMC and BYL Nair Charitable Hospital, Mumbai, Maharashtra, India.

Associate Professor

Pallavi Anil rathod, Department of Obstetrics and Gynaecology, Kasturba Hospital for Infectious Diseases, Mumbai, Maharashtra, India.

Senior Resident, Kasturba Hospital for Infectious Diseases, Mumbai, India

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