EFFECT OF PROPOLIS HONEY CANDY CONSUMPTION ON THE ACTIVITY OF LACTOPEROXIDASE IN STIMULATED SALIVA
DOI:
https://doi.org/10.22159/ijap.2019.v11s1.AR184Keywords:
Propolis, Lactoperoxidase, Saliva, FlavonoidsAbstract
Objective: This study aimed to analyze the effect of propolis honey candy consumption on lactoperoxidase (LPO) activity in stimulated saliva.
Methods: Stimulated saliva samples were collected from subjects before and after propolis honey candy consumption twice a day for 7 days, and the
LPO activity was measured by optical density using a microplate reader.
Results: The LPO activity before and after propolis honey candy consumption was found to be 0.010 and 0.013, respectively.
Conclusions: A statistically significant increase in the LPO activity after propolis honey candy consumption was observed (Wilcoxon test; p <0.05).
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unexpected results. Z Naturforsch 2002;57c:530-3.
2. Lotfy M. Biological acitvity of bee propolis in health and disease. Asian
Pac J Cancer Prev 2006;7:22-31.
3. Burdock G. Review of the biological properties and the toxicity of bee
propolis (propolis). Food Chem Toxicol 1997;36:347-63.
4. Hegazi AG. Propolis an Overview 2013. Available from: http://www.
apinetla.com.ar/congreso/c05.pdf. [Last accessed on 2014 Jun 25].
5. Marghitas L, Dezmirean DS, Margaoan R, Mihai CM. Physicochemical
characterization and antioxidant activity of transylvanian
propolis. Econ Mang Financ Mark 2011;6:1228.
6. Macpherson P. The role of saliva on oral health and disease. Dent Nurs
2013;9:568-73.
7. Bosch EH, van Doorne H, de Vries S. The lactoperoxidase system: The
influence of iodide and the chemical and antimicrobial stability over the
period of about 18 months. J Appl Microbiol 2000;89:215-24.
8. Amerongen VN. Ludah Dan Kelenjar Ludah. Yogyakarta: Gajah Mada
University Press; 1991. p. 43-59.
9. Kenneth MP, Tenovuo JO. The Lactoperoxidase System Chemistry and
Biological Significance. New York: Marcel Dekker; 1958.
10. Molan PC. The antibacterial activity of honey: 2 variation in the
potency of the antibacterial activity. Bee World 1992;73:5-28.
11. Tsai YC, Wang YH, Liou CC, Lin YC, Huang H, Liu YC, et al.
Induction of oxidative DNA damage by flavonoids of propolis: Its
mechanism and implication about antioxidant capacity. Chem Res
Toxicol 2012;25:191-6.
12. Sahlan MR. Hard candy propolis for oral health. [In Indonesia]. Depok:
Universitas Indonesia 2011; p. 1, 2, 5.
13. Sabir A. Aktivitas antibakteri flavonoid propolis trigona sp terhadap
bakteri Steptococcus mutans (in vitro). Maj Ked Gigi (Dent J) 2005;
38:135-141.
14. Cuesta A, Rodríguez A, Esteban MA, Meseguer J. In vivo effects of
propolis, a honeybee product, on gilthead seabream innate immune
responses. Fish Shellfish Immunol 2005;18:71-80.
15. Soekanto SA, Marpaung LJ, Himmatushohwah, Djais A, Darwita RR.
Efficacy of Propolis Fluoride and Nano Silver Fluoride for Inhibition of
Streptococcus mutans and Enterococcus faecalis Biofilm Formation Int
J App Pharm 2017;2:51-4.
16. Soekanto SA, Ghrena GCD, Bachtiar EW, Sahlan M. The Effect Of
Casein Phosphopeptide-Amorphous Calcium Phosphate-Propolis
Chewing Gum On Calcium and Phosphate Ion Levels in Caries-Free
Subject’s Saliva and Streptococcus Mutans Biofilm Formation. Asian J
Pharm Clin Res. 2017.174-6.
Published
05-04-2019
How to Cite
RAHMI, S. ., SARWONO, A. T. ., & SOEKANTO, S. A. . (2019). EFFECT OF PROPOLIS HONEY CANDY CONSUMPTION ON THE ACTIVITY OF LACTOPEROXIDASE IN STIMULATED SALIVA. International Journal of Applied Pharmaceutics, 11(1), 134–136. https://doi.org/10.22159/ijap.2019.v11s1.AR184
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