QUALITY PARAMETERS AND DETERMINATION OF TOTAL FLAVONOID LEVELS FROM THE HIGHEST ANTIOXIDANT ACTIVITY OF ETHANOL 70% EXTRACT JACKFRUIT PEEL (ARTOCARPUS HETEROPHYLLUS L.) BY MACERATION, REFLUX, AND ULTRASONIC METHODS

Authors

  • YUNAHARA FARIDA Faculty of Pharmacy, Pancasila University, Srengseng Sawah, Jagakarsa, South Jakarta, 12640, Indonesia
  • RAHMATUL QODRIAH Faculty of Pharmacy, Pancasila University, Srengseng Sawah, Jagakarsa, South Jakarta, 12640, Indonesia
  • SANAM NILESH Faculty of Pharmacy, Pancasila University, Srengseng Sawah, Jagakarsa, South Jakarta, 12640, Indonesia

DOI:

https://doi.org/10.22159/ijap.2022.v14s3.21

Keywords:

Jackfruit peel, Extraction methods, Antioxidant activity, Quality parameters, Flavonoids

Abstract

Objective: The aim of this study was to investigate and determination of total flavonoid levels antioxidant activity of ethanol 70% extract jackfruit peel (Artocarpus heterophyllus L.) by maceration, reflux, and ultrasonic methods

Methods: Jackfruit peel was extracted by using maceration, reflux, and ultrasonic methods with 70% of ethanol as the solvent. Antioxidant activity using DPPH free radical scavenging and determination of total flavonoid levels using colorimetric methods.

Conclusion: The results of phytochemical screening indicates that jackfruit peel contains flavonoids, saponins, tannin, and triterpenoids; the best antioxidant activity is found in the maceration method. The extract of Jackfruit peel fullfill the quality parameters requirements.

Results: The determination was carried out at the Center for Plant Conservation and Botanical Gardens-LIPI, Bogor. The results of this determination indicate that the material studied belongs to the species Artocarpus heterophyllus L.

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References

Ahmad R, Ali AM, Israf DA, Ismail NH, Shaari K, Lajis NH. Antioxidant, radical-scavenging, anti-inflammatory, cytotoxic and antibacterial activities of methanolic extracts of some Hedyotis species. Life Sci. 2005;76(17):1953-64. doi: 10.1016/j.lfs.2004.08.039, PMID 15707878.

Baliga MS, Shivashankara AR, Haniadka R, Dsouza J, Bhat HP. Phytochemistry, nutritional and pharmacological properties of Artocarpus heterophyllus Lam (jackfruit): a review. Food Res Int. 2011;44(7):1800-11. doi: 10.1016/j.foodres.2011.02.035.

Ranasinghe RASN, Maduwanthi SDT, Marapana RAUJ. Nutritional and health benefits of jackfruit (Artocarpus heterophyllus Lam.): a review. Int J Food Sci. 2019;2019:4327183. doi: 10.1155/2019/4327183, PMID 30723733.

Jagadeesh SL, Reddy BS, Swamy GSK, Gorbal K, Hegde L, Raghavan GSV. Chemical composition of jackfruit (Artocarpus heterophyllus Lam.) selections of Western Ghats of India. Food Chem. 2007;102(1):361-5. doi: 10.1016/j.foodchem. 2006.05.027.

Biworo A, Tanjung E, Iskandar K, Khairina E, Suhartono E. Antidiabetic and antioxidant activity of Jackfruit (Artocarpus heterophyllus) extract. JOMB. 2015;4(4):318-23. doi: 10.12720/jomb.4.4.318-323.

Saxena M, Saxena J, Pradhan A. Flavonoids and phenolic acids as antioxidants in plants and human health. Int J Pharm Sci Rev Res. 2012;16:130-4.

Selveraj Y, Pal DK. Biochemical changes during ripening of jackfruit (Artocarpus heterophylllus lam. J Food Sci Technol. 1989;26:304-7.

Tiwari AK, Vidyarthi AS. Nutritional evaluation of various edible fruit parts of jackfruit (Artocarpus heterophyllus) at different maturity stages. Int J Chem Pharm Rev Res. 2015;1:21-6.

Loizzo MR, Tundis R, Chandrika UG, Abeysekera AM, Menichini F, Frega NG. Antioxidant and antibacterial activities on foodborne pathogens of Artocarpus heterophyllus lam. (Moraceae) leaves extracts. J Food Sci. 2010;75(5):M291-5. doi: 10.1111/j.1750-3841.2010.01614.x, PMID 20629886.

Farid Y, Iswahyun I. Isolation, identification, and antioxidant activity of the chemical compound in ethanol extract of papaya leaves (Carica papaya L.). Asian J Pharm Clin Res. 2018;11(13):118-21. doi: 10.22159/ajpcr.2018.v11s1.26583.

Farnsworth NR. Biological and phytochemical screening of plants. J Pharm Sci. 1966;55(3):225-76. doi: 10.1002/jps.2600550302, PMID 5335471.

Harborne JB. Phytochemical methods. A guide to modern techniques of plant analysis. 2nd ed. London: Chapman & Hall; 1984.

Molyneux P. The use of the stable free radical diphenylpicrylhydrazyl (DPPH) for estimating antioxidant activity. Songklanakarin J Sci Technol. 2004;26:211-9.

Blois MS. Antioxidant determinations by the use of a stable free radical. Nature. 1958;181(4617):1199-200. doi: 10.1038/ 1811199a0.

Department of Health. Parameter standar umum ekstrak tumbuhan obat. DitJen POM, Direktorat Pengawasan Obat Tradisional; 2000. p. 13-37.

Yunahara F, Widi A, Mega EL, Diah KP. The quality parameters, total flavonoid determination and antioxidant activity compound of Andaliman fruit Andaliman fruit (Zanthoxylum Acanthopodium DC.) extract. Int J Appl Pharm. 2010;13:34-40.

Banjamahor S, Artanti N. Antioxidant properties of flavonoids. Med J lndonesia. 2014;23:239-44.

McDonald S, Prenzler PD, Antolovich M, Robards K. Phenolic content and antioxidant activity of olive extracts. Food Chem. 2001;73(1):73-84. doi: 10.1016/S0308-8146(00)00288-0.

Shui G, Leong LP. Residue from star fruit as a valuable source for functional food ingredients and antioxidant nutraceuticals. Food Chem. 2006;97(2):277-84. doi: 10.1016/ j.foodchem.2005.03.048.

Hidalgo G, Almajano M. Red fruits: extraction of antioxidants, phenolic content, and radical scavenging determination: a review. Antioxidants. 2017;6(1):1-27. doi: 10.3390/ antiox6010007.

Published

28-06-2022

How to Cite

FARIDA, Y., QODRIAH, R., & NILESH, S. (2022). QUALITY PARAMETERS AND DETERMINATION OF TOTAL FLAVONOID LEVELS FROM THE HIGHEST ANTIOXIDANT ACTIVITY OF ETHANOL 70% EXTRACT JACKFRUIT PEEL (ARTOCARPUS HETEROPHYLLUS L.) BY MACERATION, REFLUX, AND ULTRASONIC METHODS. International Journal of Applied Pharmaceutics, 14(3), 100–103. https://doi.org/10.22159/ijap.2022.v14s3.21

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