NADES EXTRACT OF GEDONG MANGO LEAVES AND MULBERRY LEAVES IN SPRAY GEL AS A SUNSCREEN

YAYAN RIZIKIYAN; INE SUHARYANI; YUNIARTI FALYA; RENNY AMELIA; MUHAMMAD NUH; LELA SULASTRI; IIN INDAWATI

doi:10.22159/ijap.2022.v14s4.PP29

Authors

YAYAN RIZIKIYAN Sekolah Tinggi Farmasi Muhammadiyah Cirebon, Jl. Cideng Indah No. 3, Kertawinangun, Kedawung, Cirebon, Jawa Barat 45153
INE SUHARYANI Sekolah Tinggi Farmasi Muhammadiyah Cirebon, Jl. Cideng Indah No. 3, Kertawinangun, Kedawung, Cirebon, Jawa Barat 45153, Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Jln. Raya Bandung-Sumedang Km. 21 Jatinangor, Kab. Sumedang 45363
YUNIARTI FALYA Sekolah Tinggi Farmasi Muhammadiyah Cirebon, Jl. Cideng Indah No. 3, Kertawinangun, Kedawung, Cirebon, Jawa Barat 45153
RENNY AMELIA Sekolah Tinggi Farmasi Muhammadiyah Cirebon, Jl. Cideng Indah No. 3, Kertawinangun, Kedawung, Cirebon, Jawa Barat 45153, Department of Pharmacology, Faculty of Pharmacy, Universitas Padjadjaran, Jln. Raya Bandung Sumedang Km. 21 Jatinangor, Kab. Sumedang 45363
MUHAMMAD NUH Sekolah Tinggi Farmasi Muhammadiyah Cirebon, Jl. Cideng Indah No. 3, Kertawinangun, Kedawung, Cirebon, Jawa Barat 45153
LELA SULASTRI Sekolah Tinggi Farmasi Muhammadiyah Cirebon, Jl. Cideng Indah No. 3, Kertawinangun, Kedawung, Cirebon, Jawa Barat 45153
IIN INDAWATI Sekolah Tinggi Farmasi Muhammadiyah Cirebon, Jl. Cideng Indah No. 3, Kertawinangun, Kedawung, Cirebon, Jawa Barat 45153

DOI:

https://doi.org/10.22159/ijap.2022.v14s4.PP29

Keywords:

Gedong mango leaves, Mulberry leaves, Spray gel, SPF, Sunscreen

Abstract

Objective: This study's purpose was to formulate a spray gel containing the combination extract of gedong mango leaves and mulberry leaves as a sunscreen preparation.

Methods: Each leaf was extracted by Natural Deep Eutectic Solvent-Maceration Assisted Extraction (NADES-MAE) method. The extract (gedong mango and mulberry leaves) formulated in Carbopol Spray Gel/GM-CarSG) in a ratio of GL and ML were 3:0.5 (GM-CarSG 1); 3:3 (GM-CarSG 2); and 3:6 (GM-CarSG 3). Furthermore, the spray gel was evaluated, and the SPF value was determined.

Results: The physical appearance, spreadability, pH, and viscosity of GM-CarSG 1, GM-CarSG 2, and GM-CarSG 3 meet the requirements. In addition, the three preparation have a sunscreen activity, with the SPF value of GM-CarSG 1, GM-CarSG 2, and GM-CarSG 3 being 2.08+0.03; 2.78+0.05; and 3.53+0.04, respectively.

Conclusion: The results showed that the combination of GL and ML extract is potentially used as a sunscreen in spray gel preparation. The best formulation is GM-CarSG 3, which has the highest SPF value among them.

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