• SRI AGUNG FITRI KUSUMA Department of Biology Pharmacy, Faculty of Pharmacy, Padjadjaran University, Sumedang, West Java, Indonesia
  • DANNI RAMDHANI Departement of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Padjadjaran University, Sumedang, Sumedang, West Java, Indonesia
  • EMMANUEL MELATI SETIAFIANTI Department of Biology Pharmacy, Faculty of Pharmacy, Padjadjaran University, Sumedang, West Java, Indonesia




Klutuk, Musa balbisiana colla, Heat, Potassium, Shigellosis


Objective: to investigate the effect of heat treatment on the potassium content and anti-shigellosis action of klutuk banana fruit flour.

Methods: The klutuk banana fruit slices were heat-treated using a validated oven under varied parameters of 30-50 °C for 15–40 h. Based on its minimum inhibitory concentration (MIC) value and the potassium analysis, the selected condition was then applied to the processing of bananas to produce stable flour. Atomic Absorption Spectrophotometry (AAS) was used to quantify the potassium concentration after the MIC value was calculated using the microbroth dilution method.

Results: The best heat treat for the anti-shigellosis activity with a MIC of 3.125 mg/ml was at 50 °C for 20 h. The amount of potassium in the flour of klutuk banana fruit that had the best anti-dysentery activity was 0.3773 mg/ml or 9.76% of the total potassium content. But according to our research, the lower water content of banana flour caused by longer drying times and higher temperatures had no effect on the existence of antimicrobial metabolites.

Conclusion: The potassium gain and anti-shigellosis action of klutuk banana fruit were thus significantly impacted by heat during the flour-processing stage.


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Kusuma SF, Mita SR, Firdayani I, Mustarichie R. Study on the antibacterial activity of fruit extracts of klutuk banana (Musa balbisiana colla) against Shigella dysenteriae ATCC 13313. Asian J Pharm Clin Res. 2017;10(7):220-3. doi: 10.22159/ajpcr.2017.v10i7.18561.

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Kusuma SF, Mita SR, Firdayani I, Mustarichie R. Study on the antibacterial activity of fruit extracts of Klutuk Banana (Musa Bbalbisiana Colla) against Shigella Dysenteriae Shigella dysenteriae ATCC 13313. Asian J Pharm Clin Res. 2017;10(7):220-3. doi: 10.22159/ajpcr.2017.v10i7.18561.



How to Cite

KUSUMA, S. A. F., RAMDHANI, D., & SETIAFIANTI, E. M. (2022). EFFECT OF HEAT TREATMENT ON POTASSIUM CONTENT AND ANTI-SHIGELLOSIS ACTIVITY OF KLUTUK BANANAS (MUSA BALBISIANA COLLA) FRUIT FLOUR. International Journal of Applied Pharmaceutics, 14(5), 60–66. https://doi.org/10.22159/ijap.2022.v14s5.10



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