A REVIEW ON RECENT ADVANCES ON STIMULI BASED SMART NANOMATERIALS FOR DRUG DELIVERY AND BIOMEDICAL APPLICATION

POONAM JOSHI; NIDHI NAINWAL; SRISHTI MORRIS; VIKAS JAKHMOLA

doi:10.22159/ijap.2023v15i5.48186

Authors

POONAM JOSHI Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun-247008, Uttarakhand, India https://orcid.org/0000-0003-0287-2438
NIDHI NAINWAL Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun-247008, Uttarakhand, India https://orcid.org/0000-0003-0117-1701
SRISHTI MORRIS Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun-247008, Uttarakhand, India
VIKAS JAKHMOLA Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun-247008, Uttarakhand, India

DOI:

https://doi.org/10.22159/ijap.2023v15i5.48186

Keywords:

Nanomedicine, Nano-bio interaction, Nanomaterials, Intelligent material, Nanoparticles, Stimuli-responsive

Abstract

The advancement of numerous interdisciplinary fields of science, engineering, and medicine has been integrated into the rapid growth of nanomedicine (NM) over the past few decades. Many aspects of NM need to be investigated, even though a few clinical successes of nanomaterials have significantly altered the landscape of disease diagnosis and treatment. One such topic is the complex interactions between NM and its post-administration chemical, physical, and biological interactions and how these interactions impact NM biological performance. Because of the increased prevalence of metabolic disorders, neurological illnesses, heart diseases, and cancer, as well as the hunt for effective therapies for these and other diseases, there is a larger demand for unique, inventive, and drug-delivery systems that can transport medications to the desired place. The many cutting-edge drug delivery systems are becoming more and more dependent on nanotechnology. In this review, developments in the field and talk about how nanomedicine interacts with the physical, chemical, and biological material, with a focus on biological stimuli research. We also show how nano-bio interaction can create a variety of multifunctional platforms of biomedical applications with a wide range. The potential difficulties and opportunities in the study of nano-bio interactions are also discussed.

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