ANTI-ACNE CREAM OF LEAVES EXTRACT OF FIG (FICUS CARICA L.) FROM CIWIDEY DISTRICT, INDONESIA, AGAINST PROPIONIBACTERIUM ACNES AND STAPHYLOCOCCUS EPIDERMIDIS

Authors

  • NYI MEKAR SAPTARINI Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran-45363, West Java, Indonesia
  • DIAH LIA AULIFA Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran-45363, West Java, Indonesia
  • RESMI MUSTARICHIE Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran-45363, West Java, Indonesia
  • RINI HENDRIANI Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran-45363, West Java, Indonesia
  • IRMA ERIKA HERAWATI Indonesian School of Pharmacy, West Java-40266, Indonesia
  • MARY JHO-ANNE T. CORPUZ Department of Pharmacy, Faculty of Pharmacy, University of Santo Tomas, Espana-1015, Manila, Philippines

DOI:

https://doi.org/10.22159/ijap.2023.v15s2.27

Keywords:

Fig leaves extract, P. acnes, S. epidermidis, Safe cream, Dose-dependent

Abstract

Objective: This study aimed to formulate and evaluate an anti-acne cream of fig leaves extract.

Methods: The methods included formulation and evaluation of anti-acne cream, antibacterial activity assay against Propionibacterium acnes and Staphylococcus epidermidis, irritancy test, and preference test. The oil-in-water creams were made with various extract concentrations (1, 2, and 3%).

Results: Greenish cream with fig fragrant, viscosity ranging from 332 to 388 cP, pH ranging from 6.69 to 7.23, and oil-in-water type. Antibacterial activity was dose-dependent, without irritancy, erythema, and edema, and the most preferred cream based on the texture and fragrance was the 3% extract formula.

Conclusion: Fig leaves extract can be made into a safe cream with antibacterial activity against P. acnes and S. epidermidis.

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Published

18-12-2023

How to Cite

SAPTARINI, N. M., AULIFA, D. L., MUSTARICHIE, R., HENDRIANI, R., HERAWATI, I. E., & CORPUZ, M. J.-A. T. (2023). ANTI-ACNE CREAM OF LEAVES EXTRACT OF FIG (FICUS CARICA L.) FROM CIWIDEY DISTRICT, INDONESIA, AGAINST PROPIONIBACTERIUM ACNES AND STAPHYLOCOCCUS EPIDERMIDIS. International Journal of Applied Pharmaceutics, 15(2), 145–148. https://doi.org/10.22159/ijap.2023.v15s2.27

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