EMERGING FRONTIERS: ADVANCEMENTS IN BIO-NONMATERIAL’S AND NON-INVASIVE STRATEGIES FOR COMBATING CANCER THROUGH PHOTO THERMAL THERAPY

YOKESH S.; TEEJESWARI R.; JALANIY V.; LOKESHVAR R.

doi:10.22159/ijap.2024v16i5.51113

Authors

YOKESH S. Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Saveetha Nagar, Chennai-602105, India https://orcid.org/0009-0009-9102-5548
TEEJESWARI R. Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Saveetha Nagar, Chennai-602105, India
JALANIY V. Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Saveetha Nagar, Chennai-602105, India
LOKESHVAR R. Department of Pharmacology, Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Saveetha Nagar, Chennai-602105, India https://orcid.org/0000-0001-6869-3446

DOI:

https://doi.org/10.22159/ijap.2024v16i5.51113

Keywords:

Bionanomaterials, Cancer, Photothermal therapy, Photothermal agents

Abstract

Cancer remained a global health challenge in 2020 and claimed approximately 10 million lives, thus rendering it the main reason for demise. Photo Thermal Therapy (PTT) has emerged as a promising approach among the various cancer therapies. PTT offers several advantages over traditional treatments such as surgery, chemotherapy, and Radiotherapy due to its precise tumor targeting and reduced damage to healthy tissues. Photo Thermal Agents (PTAs) are central to PTT and selectively kill cancer cells by converting near-infrared light into heat. However, some PTAs exhibit toxicity and remain in the body's Reticulo Endothelial System (RES), limiting their clinical utility. To address this issue, scientists are looking at putrescible nano-photothermal compounds. This study talks about the effects of PTT and other cancer treatment techniques on patient health, stares at the process beneath PTT, and highlights recent bio-nonmaterial’s utilized in PTT. It also looks at how low temperatures and brightly coloured light might be used to improve PTT efficacy.

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