FLAVONOIDS IN ACACIA CATECHU BARK EXTRACTS AND BIBLIOGRAPHIC ANALYSIS IN GUNA, MADHYA PRADESH, INDIA

Authors

  • ARCHANA TIWARI Department of Botany, Government P. G. College Guna-473001, Madhya Pradesh, India
  • AVINASH TIWARI Jiwaji University, Gwalior-474011, Madhya Pradesh, India

DOI:

https://doi.org/10.22159/ijpps.2024v16i6.50939

Keywords:

Acacia catechu, Flavonoids, Dimension AI, Acetone extract, Bark, Bibliographic analysis, Antioxidant

Abstract

Objective: The objective of this work is to examine the overall flavonoid content in bark samples of Acacia catechu obtained from the Guna region of Madhya Pradesh, India, using several extraction methods. Furthermore, this study has incorporated current literature, conducted bibliographic analysis, examined co-authorship studies, and gathered other pertinent material to augment comprehension and underscore the importance of the research.

Methods: For the purpose of this experiment, a total of thirty samples of test plants were gathered from the research region throughout various seasons. Each individual sample was prepared with six different solvents. Following this, a standardized laboratory technique was used to undertake quantitative testing. The bibliographic analysis was conducted using Dimension AI and VOS viewer software in the timeframe of 1975-2024 (till March 8, 2024).

Results: Findings indicated that the polar organic solvents methanol, ethanol, acetone, and the aqueous extracts were shown to display a substantial quantity of flavonoids, chloroform extracts exhibited negligible and benzene extracts were found to be entirely devoid of the same. The comparative bibliographic investigations have confirmed the need to study the possible medicinal properties of test plants in the Guna region.

Conclusion: This preliminary study has the potential to identify new, economically viable, and readily available sources of flavonoids, which are natural antioxidants present in the indigenous flora of the Guna region.

Downloads

Download data is not yet available.

References

Kumar S, Pandey AK. Chemistry and biological activities of flavonoids: an overview. Scientific World Journal. 2013;2013:162750. doi: 10.1155/2013/162750, PMID 24470791.

Roy A, Khan A, Ahmad I, Alghamdi S, Rajab BS, Babalghith AO. Flavonoids a bioactive compound from medicinal plants and its therapeutic applications. BioMed Res Int. 2022;2022:5445291. doi: 10.1155/2022/5445291, PMID 35707379.

Ma EZ, Khachemoune A. Flavonoids and their therapeutic applications in skin diseases. Arch Dermatol Res. 2023;315(3):321-31. doi: 10.1007/s00403-022-02395-3, PMID 36129522.

Tan Z, Halter B, Liu D, Gilbert ER, Cline MA. Dietary flavonoids as modulators of lipid metabolism in poultry. Front Physiol. 2022;13:863860. doi: 10.3389/fphys.2022.863860, PMID 35547590.

Khan J, Deb PK, Priya S, Medina KD, Devi R, Walode SG. Dietary flavonoids: cardioprotective potential with antioxidant effects and their pharmacokinetic, toxicological and therapeutic concerns. Molecules. 2021;26(13):4021. doi: 10.3390/molecules26134021, PMID 34209338.

Abdou MO, Sanni AA, Lagnika L. Antioxidant activity and total phenolic, flavonoid and flavonol contents of the bark extracts of Acacia ataxacantha. J Pharmacogn Phytochem. 2015;4(2):172-8.

Tiwari A, Tiwari A. An assessment of the relative antioxidant activity of bark extracts of Acacia catechu by in vitro free radical scavenging analysis. Int J Pharm Pharm Sci. 2024;16(1):30-6. doi: 10.22159/ijpps.2024v16i1.49763.

Patil A, Modak M. Comparative evaluation of oxidative stress modulating and DNA protective activities of aqueous and methanolic extracts of Acacia catechu. Medicines (Basel). 2017;4(3):65. doi: 10.3390/medicines4030065, PMID 28930279.

Pharma T, Roy A. Acacia catechu wild-a gift from ayurveda to mankind-a review. The Pharma Research A Journal. 2011;2:273-93.

Satpudke S, Khandekar S, Pansare T. Review on Khadira (Acacia catechu Wild.) with special reference to prameha (Diabetes). Int J Herb Med. 2020;8(1):1-5.

Venugopalan V. Pharmacognostic and chromatographic profiling of khadira (Acacia catechu Linn. F.) wild). Int J Adv Res. 2018;6(8):417-22.

Febrina E, Asnawi A, Abdulah R, Lestari K, Supratman U. Identification of flavonoids from Acalypha indica l. (euphorbiaceae) as caspase-3 activators using molecular docking and molecular dynamics. Int J Appl Pharm. 2022;14(5):162-6.

Monika P, Basavaraj BV, Chidambara Murthy KN, Ahalya N, Bharath S. Enrichment of in vivo efficacy of catechin-rich extract with the application of nanotechnology. Int J App Pharm. 2018;10(5):281-8. doi: 10.22159/ijap.2018v10i5.29569.

Negi BS, Dave BP. In vitro antimicrobial activity of Acacia catechu and its phytochemical analysis. Indian J Microbiol. 2010;50(4):369-74. doi: 10.1007/s12088-011-0061-1, PMID 22282602.

Kumari M, Radha KM, Kumar M, Zhang B, Amarowicz R, Puri S. Acacia catechu (L.f.) willd: a review on bioactive compounds and their health-promoting functionalities. Plants (Basel). 2022;11(22):3091. doi: 10.3390/plants11223091, PMID 36432824.

Ram DS, Sharma DR, Kotecha PM, Chaudhary DK. Preliminary pharmacognosy evaluation of the bark of acacia catechu (Wild.). IRJAY. 2021;04(4):1-9. doi: 10.47223/IRJAY.2021.4420.

Tiwari A, Tiwari A. Amazing antimicrobial and wound healing potential of Acacia catechu bark extracts-a review. Asian J Pharm Clin Res. 2021;14(10):1-7. doi: 10.22159/ajpcr.2021.v14i10.43009.

Baranwal A, Aggarwal P, Rai A, Kumar N. Pharmacological actions and underlying mechanisms of catechin: a review. Mini Rev Med Chem. 2022;22(5):821-33. doi: 10.2174/1389557521666210902162120, PMID 34477517.

Liaqat W, Altaf MT, Barutçular C, Zayed EM, Hussain T. Drought and sorghum: a bibliometric analysis using VOS viewer. J Biomol Struct Dyn. 2023:1-13. doi: 10.1080/07391102.2023.2269279, PMID 37837436.

Singh P, Gargi B, Semwal P, Mishra J, Thapliyal A. Global research trends, publication characteristics and knowledge domains of plant reproductive biology: a bibliometric and knowledge mapping analysis of 50 y Acta Ecol Sin. 2023. doi: 10.1016/j.chnaes.2023.08.010.

Yadava SM, Patrick HS, Ananth CV, Rosen T, Brandt JS. Top-cited articles in the Journal: a bibliometric analysis. Am J Obstet Gynecol. 2019;220(1):12-25. doi: 10.1016/j.ajog.2018.11.1091, PMID 30452887.

Tiwari A, Tiwari A. Qualitative analysis of tannins in different bark extracts of Acacia catechu collected from Guna district, Madhya Pradesh, India. World J Biol Pharm Health Sci. 2023;16(2):156-64.

Azwanida NN. A review on the extraction methods uses in medicinal plants, principle, strength, and limitation. Med Aromat Plants. 2015;4(3):1000196.

Agrawal J, Kar A, Panda S. Synergistic action of phytochemicals augments their antioxidative efficacy: an in vitro comparative study. Asian J Pharm Clin Res. 2013;6(8):121-6.

Herzog C, Hook D, Konkiel S. Dimensions: bringing down barriers between scientometricians and data. Quant Sci Stud. 2020;1(1):387-95. doi: 10.1162/qss_a_00020.

Hook DW, Porter SJ, Draux H, Herzog CT. Real-time bibliometrics: dimensions as a resource for analyzing aspects of COVID-19. Front Res Metr Anal. 2020;5:595299. doi: 10.3389/frma.2020.595299, PMID 33969256.

Panche AN, Diwan AD, Chandra SR. Flavonoids: an overview. J Nutr Sci. 2016;5(5):e47. doi: 10.1017/jns.2016.41, PMID 28620474.

Lavanya M, Ramakrishnan P. An overview of discrete nano formulated flavonoids and its implication in cancer. Int J Appl Pharm. 2023;15(6):69-75.

Patel JD, Kumar V, Bhatt SA. Antimicrobial screening and phytochemical analysis of the resin part of Acacia catechu. Pharm Biol. 2009;47(1):34-7. doi: 10.1080/13880200802400527.

Waseem U, Jafri SR, Khalid S, Qureshi F, Majeed N, Akif U. Anti-inflammatory activity of Acacia catechu-bark aqueous solution in aspirin induced gastric ulcer in rodents. Int J Community Med Public Health. 2021;8(12):5649. doi: 10.18203/2394-6040.ijcmph20214551.

Pawar RV, Balasubramaniam A, Pawar S, Bansode A, Devhadrao NV, Salunke M. The molecular docking studies of phytoconstituents from Acacia catechu for B cell dysfunction causing diabetes. J Pharm Negat. 2022;13:4412-21.

Sasikala P, Pugazhendy K. Antioxidant and cytotoxic agent from Acacia catechu stem bark against MCF-7 cell line. AJBLS. 2022;11(1):77-81. doi: 10.5530/ajbls.2022.11.11.

Anurukvorakun O, Lahpun N, Boonruang R. Formulation strategy, stability issues, safety and efficacy evaluations of Acacia catechu whitening cream. Int J App Pharm. 2019;11(2):91-6. doi: 10.22159/ijap.2019v11i2.30632.

Thangavelu L, Singh AK. Preliminary phytochemical analysis and in vitro antibacterial activity of Acacia catechu wild. Bark against Streptococcus mitis, Streptococcus sanguis, and Lactobacillus acidophilus. Nt J Phytomedicine. 2011;3:579-84.

Rungsung W, Ratha KK, Dutta S, Dixit AK, Hazra J. Secondary metabolites of plants in drugs discovery. World J Pharm Res. 2015;4(7):604-13.

Kadian R, Parle M, Sharma K. Phytopharmacology of Acacia catechu wild: a review world. Int J Pharm Pharm Sci. 2014;3(11):1380-9.

Adhikari B, Aryal B, Bhattarai BR. A comprehensive review on the chemical composition and pharmacological activities of Acacia catechu (L.F.) wild. J Chem. 2021;11:2575598.

Al-Jubori Y, Ahmed NT, Albusaidi R, Madden J, Das S, Sirasanagandla SR. The efficacy of gum arabic in managing diseases: a systematic review of evidence-based clinical trials. Biomolecules. 2023;13(1):138. doi: 10.3390/biom13010138, PMID 36671523.

Batiha GE, Akhtar N, Alsayegh AA, Abusudah WF, Almohmadi NH, Shaheen HM. Bioactive compounds, pharmacological actions, and pharmacokinetics of genus acacia. Molecules. 2022;27(21):7340. doi: 10.3390/molecules27217340, PMID 36364163.

George VC, Dellaire G, Rupasinghe HP. Plant flavonoids in cancer chemoprevention: role in genome stability. J Nutr Biochem. 2017;45:1-14. doi: 10.1016/j.jnutbio.2016.11.007, PMID 27951449.

Muthukala B, Sivakumari K, Ashok K. Antioxidant and anti-inflammatory potential of quercetin. Int J Curr Pharm Res. 2022;3:58-9.

Chebil L, Humeau C, Anthoni J, Dehez F, Engasser JM, Ghoul M. Solubility of flavonoids in organic solvents. J Chem Eng Data. 2007;52(5):1552-6. doi: 10.1021/je7001094.

Burnett BP, Jia Q, Zhao Y, Levy RM. A medicinal extract of Scutellaria baicalensis and Acacia catechu acts as a dual inhibitor of cyclooxygenase and 5-lipoxygenase to reduce inflammation. J Med Food. 2007;10(3):442-51. doi: 10.1089/jmf.2006.255, PMID 17887937.

Lewis ED, Crowley DC, Guthrie N, Evans M. Role of Acacia catechu and Scutellaria baicalensis in enhancing immune function following influenza vaccination of healthy adults: a randomized, triple-blind, placebo-controlled clinical trial. J Am Nutr Assoc. 2023;42(7):678-90. doi: 10.1080/27697061.2022.2145525, PMID 36413261.

Imran M, Thabet HK, Alaqel SI, Alzahrani AR, Abida A, Alshammari MK. The therapeutic and prophylactic potential of quercetin against COVID-19: an outlook on the clinical studies, inventive compositions, and patent literature. Antioxidants (Basel). 2022;11(5):876. doi: 10.3390/antiox11050876, PMID 35624740.

Abdallah M, Neseem DI, Elgazayerly ON, Abdelbary AA. Topical delivery of quercetin loaded transfersomes for wound treatment: in vitro and in vivo evaluation. Int J App Pharm. 2021;13(5):189-97. doi: 10.22159/ijap.2021v13i5.41345.

Saeedi Boroujeni A, Mahmoudian Sani MR. Anti-inflammatory potential of quercetin in COVID-19 treatment. J Inflamm (Lond). 2021;18(1):3. doi: 10.1186/s12950-021-00268-6, PMID 33509217.

Agidew MG. Phytochemical analysis of some selected traditional medicinal plants in Ethiopia. Bull Natl Res Cent. 2022;46(1):87. doi: 10.1186/s42269-022-00770-8.

Shah J, Patel S, Bhairy S, Hirlekar R. Formulation optimization, characterization and in vitro anti-cancer activity of curcumin loaded nanostructured lipid carriers. Int J Curr Pharm Sci. 2022;14(1):31-43. doi: 10.22159/ijcpr.2022v14i1.44110.

Tupa B, Uspenskaya EV, Potanina OG, Boyko NN, Nasser RA. Determination of total carbohydrates, flavonoids, organic acids, macro-and microelements in wolfberry (Lycium barbarum l.) fruit cultivated in albania. Int J Pharm Pharm Sci. 2022;14(6):1-8. doi: 10.22159/ijpps.2022v14i6.44375.

Collares LJ, Turchen LM, Guedes RN. Research trends, biases, and gaps in phytochemicals as insecticides: literature survey and meta-analysis. Plants (Basel). 2023;12(2):318. doi: 10.3390/plants12020318, PMID 36679031.

Guerrero Bote VP, Chinchilla Rodriguez Z, Mendoza A, de Moya Anegon F. Comparative analysis of the bibliographic data sources dimensions and scopus: an approach at the country and institutional levels. Front Res Metr Anal. 2020;5:593494. doi: 10.3389/frma.2020.593494, PMID 33870055.

Published

01-06-2024

How to Cite

TIWARI, A., and A. TIWARI. “FLAVONOIDS IN ACACIA CATECHU BARK EXTRACTS AND BIBLIOGRAPHIC ANALYSIS IN GUNA, MADHYA PRADESH, INDIA”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 16, no. 6, June 2024, pp. 46-55, doi:10.22159/ijpps.2024v16i6.50939.

Issue

Section

Original Article(s)