FLAVONOIDS IN ACACIA CATECHU BARK EXTRACTS AND BIBLIOGRAPHIC ANALYSIS IN GUNA, MADHYA PRADESH, INDIA

ARCHANA TIWARI; AVINASH TIWARI

doi:10.22159/ijpps.2024v16i6.50939

Authors

ARCHANA TIWARI Department of Botany, Government P.G. College Guna-473001, Madhya Pradesh, India
AVINASH TIWARI Jiwaji University, Gwalior-474011, Madhya Pradesh, India

DOI:

https://doi.org/10.22159/ijpps.2024v16i6.50939

Keywords:

Acacia catechu, Flavonoids, Dimension AI, Acetone extract, Bark, Bibliographic analysis, Antioxidant

Abstract

Objective: The objective of this work is to examine the overall flavonoid content in bark samples of Acacia catechu obtained from the Guna region of Madhya Pradesh, India, using several extraction methods. Furthermore, this study has incorporated current literature, conducted bibliographic analysis, examined co-authorship studies, and gathered other pertinent material to augment comprehension and underscore the importance of the research.

Methods: For the purpose of this experiment, a total of thirty samples of test plants were gathered from the research region throughout various seasons. Each individual sample was prepared with six different solvents. Following this, a standardized laboratory technique was used to undertake quantitative testing. The bibliographic analysis was conducted using Dimension AI and VOSviewer software in the timeframe of 1975-2024 (till March 8, 2024).

Results: Findings indicated that the polar organic solvents methanol, ethanol, acetone, and the aqueous extracts were shown to display a substantial quantity of flavonoids, chloroform extracts exhibited negligible and benzene extracts were found to be entirely devoid of the same. The comparative bibliographic investigations have confirmed the need to study the possible medicinal properties of test plants in the Guna region.

Conclusion: This preliminary study has the potential to identify new, economically viable, and readily available sources of flavonoids, which are natural antioxidants present in the indigenous flora of the Guna region.

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References

Kumar S, Pandey AK. Chemistry and Biological Activities of Flavonoids: An Overview. Sci World J. 2013; 2013:162750.

Roy A, Khan A, Ahmad I, Alghamdi S, Rajab BS, Babalghith AO, Alshahrani MY, Islam S, Islam MR. Flavonoids a Bioactive Compound from Medicinal Plants and Its Therapeutic Applications. Biomed Res Int. 2022; 2022:5445291.

Ma EZ, Khachemoune A. Flavonoids and their therapeutic applications in skin diseases. Arch Dermatol Res. 2023; 315(3):321-31.

Tan Z, Halter B, Liu D, Gilbert ER, Cline MA. Dietary Flavonoids as Modulators of Lipid Metabolism in Poultry. Front Physiol. 2022; 13:863860.

Khan J, Deb PK, Priya S, Medina KD, Devi R, Walode SG, Rudrapal M. Dietary Flavonoids: Cardioprotective Potential with Antioxidant Effects and Their Pharmacokinetic, Toxicological and Therapeutic Concerns. Molecules. 2021; 26(13):4021.

Abdou MO, Sanni AA, and Lagnika L. Antioxidant activity and total phenolic, flavonoid and flavonol contents of the bark extracts of Acacia ataxacantha. J Pharmacogn Phytochem 2015; 4(2):172-8.

Tiwari A, Tiwari A. An assessment of the relative antioxidant activity of bark extracts of Acacia catechu by in vitro free radical scavenging analysis. Int J Pharm Pharm Sci. 2024; 16(1):30-6.

Patil A, Modak M. Comparative Evaluation of Oxidative stress modulating and DNA protective activities of aqueous and methanolic extracts of Acacia catechu. Medicines (Basel). 2017; 4(3):65.

Pharma T, Roy A. The Pharma Research, A Journal “Acacia catechu Wild-A Gift from Ayurveda to Mankind”- A Review. T Ph Res. 2011; 2: 273–93.

Satpudke S, Khandekar S, Pansare T. Review on Khadira (Acacia catechu Wild.) With Special Reference to Prameha (Diabetes). Int J Herb Med. 2020; 8(1): 1-5.

Venugopalan V. Pharmacognostic and Chromatographic Profiling of Khadira (Acacia catechu Linn.F.) Wild). Int J Adv Res. 2018; 6(8): 417–22.

Febrina E, Asnawi A, Abdulah R, Lestari K, Supratman U. (2022). Identification of flavonoids from Acalypha indica l. (euphorbiaceae) as caspase-3 activators using molecular docking and molecular dynamics. Int J App Pharm. 2022; 14(5):162–6.

Monika P, Basavaraj BV, Chidambara Murthy KN, Ahalya N, Bharath S. Enrichment of in vivo efficacy of catechin rich extract with the application of nanotechnology. Int J App Pharm. 2018; 10(5), 281–8.

Negi BS, Dave BP. In Vitro antimicrobial activity of Acacia catechu and its phytochemical analysis. Indian J Microbiol. 2010; 50(4):369-74.

Kumari M, Radha, Kumar M, Zhang B, Amarowicz R, Puri S, Pundir A, Rathour S, Kumari N, Chandran D, Dey A, Sharma N, Rajalingam S, Mohankumar P, Sandhu S, Pant N, Ravichandran RP, Subramani M, Pandi K, Muthukumar M, Zengin G, Mekhemar M, Lorenzo JM. Acacia catechu (L.f.) Willd.: A Review on Bioactive Compounds and Their Health Promoting Functionalities. Plants (Basel). 2022;11(22):3091.

Ram S, Sharma R, Kotecha M, Chaudhary K. Preliminary Pharmacognosy Evaluation of the Bark of Acacia catechu (Wild.). Int J Ayurveda Res. 2021; 4(4):1–9.

Tiwari A, Tiwari A. Amazing Antimicrobial and Wound Healing Potential of Acacia catechu Bark Extracts-A Review. Asian J Pharm Clin Res. 2021; 14(10):1-7.

Baranwal A, Aggarwal P, Rai A, Kumar N. Pharmacological Actions and Underlying Mechanisms of Catechin: A Review. Mini-Rev Med Chem. 2022; 22(5), 821–33.

Liaqat W, Altaf MT, Barutçular C, Zayed EM, Hussain T. Drought and sorghum: a bibliometric analysis using VOS viewer. J Biomol Structure Dynam. 2023; 1–13.

Singh P, Gargi B, Semwal P, Mishra J, Thapliyal A. Global research trends, publication characteristics and knowledge domains of plant reproductive biology: A bibliometric and knowledge mapping analysis of 50 years. Acta Ecologica Sinica. 2023 (Article in press).

Yadava SM, Patrick HS, Ananth CV, Rosen T, Brandt JS. Top-cited articles in the Journal: a bibliometric analysis. Am J Obstet & Gynecol. 2019; 220(1):12–25.

Tiwari A, Tiwari A. Qualitative analysis of tannins in different bark extracts of Acacia catechu collected from Guna district, Madhya Pradesh, India. World J Biol Pharm & Health Sci. 2023; 16(2):156–64.

Azwanida NN. A review on the extraction methods uses in medicinal plants, principle, strength, and limitation. Med Aromat Plants. 2015; 4(3):1000196.

Agrawal J, Kar A, Panda S. Synergistic action of phytochemicals augments their antioxidative efficacy: an in vitro comparative study. Asian J Pharm Clin Res. 2013; 6(8):121–6.

Herzog C, Hook D, Konkiel S (2020). Dimensions: Bringing down barriers between scientometricians and data. Quantitative Sci Studies. 2020; 1(1):387–95.

Hook DW, Porter SJ, Draux H, & Herzog CT. Real-Time Bibliometrics: Dimensions as a Resource for Analyzing Aspects of COVID-19. Frontiers in Research Metrics and Analytics, 2021;5:595299.

Panche AN, Diwan AD, Chandra SR. Flavonoids: an overview. J Nutr Sci. 2016; 29;5:e47.

Lavanya M, Ramakrishnan P. An overview of discrete nano formulated flavonoids and its implication in cancer. Int J App Pharm. 2023;15(6):69–75.

Patel J D, Kumar V, Bhatt S A. Antimicrobial Screening and Phytochemical Analysis of The Resin Part of Acacia catechu. Pharm Biol. 2009; 47(1): 34–37.

Waseem U, Jafri SR, Khalid S, Qureshi F, Majeed N, Akif U. Anti-Inflammatory Activity of Acacia catechu- Bark Aqueous Solution in Aspirin Induced Gastric Ulcer in Rodents. Int J Community Med Public Health. 2021; 8(12): 5649.

Pawar RV, Balasubramaniam A, Pawar S, Bansode A, Devhadrao N V, Salunke M. The Molecular Docking Studies of Phytoconstituents from Acacia catechu for B cell Dysfunction Causing Diabetes. J Pharm Negat. 2022; 13:4412–21.

Sasikala P, Pugazhendy K. Antioxidant and Cytotoxic Agent from Acacia catechu Stem Bark Against MCF-7 Cell Line. Asian J Biol Life Sci. 2022; 11(1):77–81.

Anurukvorakun O, Lahpun N, Boonruang R. Formulation strategy, stability issues, safety and efficacy evaluations of Acacia catechu whitening cream. Int J App Pharm. 2019; 11(2), 91–6.

Thangavelu L, Singh AK. Preliminary Phytochemical Analysis and In Vitro Antibacterial Activity of Acacia catechu Wild. Bark against Streptococcus mitis, Streptococcus sanguis, and Lactobacillus acidophilus. Nt J Phytomedicine. 2011; 3:579-84.

Rungsung W, Ratha KK, Dutta S, Dixit AK, Hazra J. Secondary metabolites of plants in drugs discovery. World J Pharm Res. 2015; 4(7):604–13.

Kadian R, Parle M, Sharma K. Phytopharmacology of Acacia catechu Wild: A review World. Int J Pharm Pharm Sci. 2014; 3(11):1380-9.

Adhikari B, Aryal B, Bhattarai BR. A comprehensive review on the chemical composition and pharmacological activities of Acacia catechu (L.F.) Wild. J chem. 2021; (11):2575598.

Al-Jubori Y, Ahmed NTB, Albusaidi R, Madden J, Das S, Sirasanagandla SR. The Efficacy of Gum Arabic in Managing Diseases: A Systematic Review of Evidence-Based Clinical Trials. Biomolecules. 2023; 13(1):138.

Batiha, GES, Akhtar N, Alsayegh AA, Abusudah WF, Almohmadi NH, Shaheen HM, Singh TG, De Waard M. Bioactive Compounds, Pharmacological Actions, and Pharmacokinetics of Genus Acacia. Molecules. 2022; 27(21):7340.

George VC, Dellaire G, Rupasinghe HPV. Plant flavonoids in cancer chemoprevention: role in genome stability. J Nutritional Biochem. 2017; 45:1–14.

Muthukala B, Sivakumari K, Ashok K. Antioxidant and anti-inflammatory potential of quercetin. Int J Curr Pharm Res. 2022; 3:58-9.

Chebil L, Humeau C, Anthoni J, Dehez F, Engasser JM, Ghoul M. (2007). Solubility of Flavonoids in Organic Solvents. J Chemic & Engineer Data. 2007; 52(5):1552–6.

Burnett BP, Jia Q, Zhao Y, Levy RM. A Medicinal Extract of Scutellaria baicalensis and Acacia catechu Acts as A Dual Inhibitor of Cyclooxygenase and 5-Lipoxygenase to Reduce Inflammation. J Med Food. 2007; 10(3):442-51.

Lewis ED, Crowley DC, Guthrie N, Evans M. Role of Acacia catechu and Scutellaria baicalensis in Enhancing Immune Function Following Influenza Vaccination of Healthy Adults: A Randomized, Triple-Blind, Placebo-Controlled Clinical Trial. J Am Nutr Assoc. 2023; 42(7):678-90.

Imran M, Thabet HK, Alaqel SI, Alzahrani AR, Abida A, Alshammari MK, Kamal M, Diwan A, Asdaq SMB, Alshehri S. The Therapeutic and Prophylactic Potential of Quercetin against COVID-19: An Outlook on the Clinical Studies, Inventive Compositions, and Patent Literature. Antioxidants (Basel). 2022; 11(5):876.

Abdallah M, Neseem DI, Elgazayerly ON, Abdelbary AA. Topical delivery of quercetin loaded transfersomes for wound treatment: in vitro and in vivo evaluation. Int J App Pharm. 2021; 13(5):189–97.

Saeedi-Boroujeni A, Mahmoudian-Sani MR. Anti-inflammatory potential of quercetin in COVID-19 treatment. J Inflamm (Lond). 2021; 18(1):3.

Agidew MG. Phytochemical analysis of some selected traditional medicinal plants in Ethiopia. Bull Natl Res Cent. 2022; 46(1):87.

Shah J, Patel S, Bhairy S, Hirlekar R. Formulation optimization, characterization and in vitro anti-cancer activity of Curcumin loaded nanostructured lipid carriers. Int J Curr Pharm. 2022; 14(1):31–43.

Tupa B, Uspenskaya EV, Potanina OG, Boyko NN, Nasser RAH. Determination of total carbohydrates, flavonoids, organic acids, macro-and microelements in wolfberry (Lycium barbarum l.) Fruit cultivated in albania. Int J Pharm Pharm Sci. 2022; 14(6):1-8.

Collares LJ, Turchen LM, Guedes RNC. Research Trends, Biases, and Gaps in Phytochemicals as Insecticides: Literature Survey and Meta-Analysis. Plants. 2023; 12(2):318.

Guerrero-Bote VP, Chinchilla-Rodriguez Z, Mendoza A, de Moya-Anegon F. Comparative Analysis of the Bibliographic Data Sources Dimensions and Scopus: An Approach at the Country and Institutional Levels. Front Res Metr Anal. 2021; 5:593494.