EFFECT OF VARIATIONS OF BETA VULGARIS EXTRACTS ON MASKING THE BITTER TASTE OF MOMORDICA CHARANTIA EXTRACT SYRUP

Authors

  • Sutriyo Laboratory of Pharmaceutics and Pharmaceutical Technology Development, Faculty of Pharmacy, Universitas Indonesia, Depok 16424,
  • Raditya Iswandana Laboratory of Pharmaceutics and Pharmaceutical Technology Development, Faculty of Pharmacy, Universitas Indonesia, Depok 16424,
  • Elisa Nur Widiya Laboratory of Pharmaceutics and Pharmaceutical Technology Development, Faculty of Pharmacy, Universitas Indonesia, Depok 16424,

DOI:

https://doi.org/10.22159/ijap.2018.v10s1.34

Keywords:

Momordica charantia L, Bitter melon, Formulation of syrup preparation, Beta vulgaris

Abstract

Objective: This study aimed to obtain a formula with an optimal sweetener concentration of beet extract that can cover the bitter taste of bitter melon
and confer optimal physical properties on the syrup.
Methods: The syrups were prepared by mixing bitter melon extract, sucrose, beet extract, sorbitol, sodium benzoate, strawberry essence, and
demineralized water. The control formula and formulas 1, 2, and 3 contained beet extract at concentrations of 0% and 10%, 15%, and 20%, respectively.
All formulas were evaluated to determine their physical properties, stability, and bitterness. The bitterness was tested on 30 respondents, with data
being analyzed using Wilcoxon's test on SPSS software.
Results and Conclusion: Formula 3 with 20% beet extract was identified as the best formula for masking bitter taste because it had a significantly
better average value than the other formulas (p<0.05) and the highest bitterless taste percentage (86.67%), with physical properties of a brownishblack
color, odor of mixture of strawberry and dominant beet, a sweet and dominant beet taste, pH 5.46, and specific gravity of 1.228 g/mL.

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References

Sharma S, Tandon S, Semwal B, Singh, K. Momordica charantia

Linn: A comprehensive review on bitter remedy. J Pharm Res Opin

;1:42-7.

National Agency of Drug and Food Control of Republic of Indonesia.

Identify some plants that people use as an antidiabetic to help lower

blood sugar levels. InfoPOM 2004;5:11.

Gupta M, Sharma S, Gautam A, Bhadauria R. Momordica charantia

Linn. (Karela): Nature’s silent healer. Int J Pharm Sci Rev Res

;11:32.

United States Department of Agriculture Agricultural Research Service.

Basic Report: 11080, Beets, Raw. USDA; 2014. Available from: https://

www.ndb.nal.usda.gov/ndb/foods/show/2863?fgcd=&manu=&lfacet=

&format=&count=&max=50&offset=&sort=default&order=

asc&qlookup=11080&ds. [Last retrieved on 2016 Oct 16].

Kaushik A, Chauhan V, Sudha D. Formulation and evaluation of herbal

cough syrup. Eur J Pharm Med Res 2016;3:517-22.

Indonesian Ministry of Health. Farmakope Indonesia. 5th ed. Jakarta:

Indonesian Ministry of Health; 2014. p. 1553-63.

Sandhyarani G, Kumar K. Development and evaluation of herbal syrup

from Couroupita guianensis used as expectorant. Asian J Pharm Sci

Technol 2014;4:101-3.

Maheshwari R, Rajagopalan R. Formulation and evaluation of

paracetamol syrup made by mixed solvency concept. Sch Res Lib

;4:170-4.

Anand V, Kharb V, Kataria M, Kukkar V, Choudhury P. Taste assesment

trials for sensory analysis of oral pharmaceutical products. Pak J Pharm

Sci 2008;21:438-50.

Husen R, Yamlean P, Citraningtyas G. Formulation and evaluation

of Sida rhombifolia L. leaf extract syrup. Pharm J Ilmiah Farmasi

;4:136.

United States Department of Agriculture Food Safety and Inspection

Service. How Temperatures Affect Food; 2017. USDA. Available from:

https://www.fsis.usda.gov/shared/PDF/How_Temperatures_Affect_

Food.pdf. [Last retrieved on 2017 Jul 06].

Kludt E, Okom C, Brinkmann A, Schild D. Integrating temperature

with odor processing in the olfactory bulb. J Neurosci 2015;35:892.

Ashton J, Geary L. The Effects of Temperature on pH Measurement.

County Clare: Technical Services Department, Reagecon Diagnostics

Ltd; 2006. p. 1-7. Retrieved from: https://www.reagecon.com/pdf/

technical papers/Effects of_Temperature_on_pH v4-_TSP-01-2.pdf.

Sudam N, Manish B, Ritesh M, Sachin P, Ratnaparkhi MP, Shilpa C.

Evaluation of various natural suspending agents for its suspending

behaviour using paracetamol as model drug for suspension. Asian J

Pharma Clin Res 2012;5:183-6.

Jordan R, Jacobs S. The Effect of pH at Different Temperatures on

the Growth of Bacterium Cofi with a Constant Food Supply. London:

The Physiology Institute, University College of South Wales and

Monmouthshire, Cardiff, and the Bacteriological Laboratory, Imperial

College of Science and Technology; 2010. p. 15-23.

Chandran J, Nisha P, Singhal R, Pandit A. Degradation of color

in beetroot (Beta vulgaris L.): A kinetics study. J Food Sci Tech

;51:2678-84.

Published

20-12-2018

How to Cite

Sutriyo, Iswandana, R., & Widiya, E. N. (2018). EFFECT OF VARIATIONS OF BETA VULGARIS EXTRACTS ON MASKING THE BITTER TASTE OF MOMORDICA CHARANTIA EXTRACT SYRUP. International Journal of Applied Pharmaceutics, 10(1), 159–164. https://doi.org/10.22159/ijap.2018.v10s1.34

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