IMPACT OF A PHARMACIST-LED PATIENT EDUCATION INITIATIVE ON GLYCEMIC CONTROL OF PATIENTS WITH TYPE 2 DIABETES MELLITUS: A SINGLE-CENTER EXPERIENCE IN WEST JAKARTA, INDONESIA
Keywords:Hemoglobin A1c, Patient adherence, Type 2 diabetes mellitus, Drug information, Booklet, Pharmacist
Objective: This study aimed to evaluate the effect of the provision of drug-related information and patient education booklets on the hemoglobin A1c
(HbA1c) levels of patients with type 2 diabetes mellitus.
Methods: This prospective study was conducted at the Kembangan Health Center, West Jakarta, Indonesia, from March to June 2017. A total of
30 patients were divided into two equal groups: In addition to routine treatment, patients in the intervention group received drug-related information
and patient education booklet, while those in the control group received no additional intervention. The provision of drug information was through
direct education as well as through telephone, short messages, and booklet. HbA1c level was measured as a surrogate measure of treatment adherence.
HbA1c concentration was measured at baseline and 11 weeks after the intervention.
Results: Mean HbA1c level in the intervention group decreased from 8.05Â±0.91% at week 0 to 6.92Â±0.47% at week 11 after intervention (p<0.05).
Conclusion: In this study, provision of drug information and patient education booklets helped to improve the patient compliance.
IDF. Diabetes Atlas. 6th ed. IDF; 2015. Available from: http://www.idf.
org/diabetesatlas. [Last accessed on 2017 Mar 25].
Adisa R, Fekeye TO, Fasanmade A. Medication adherence among
ambulatory patients with Type 2 diabetes in tertiary health care setting
in Southwestern Nigeria. Pharm Pract 2011;9:72-81.
Perkeni. Consensus on the Management and Prevention of the
Type 2 Diabetes Mellitus in Indonesia in 2015. Jakarta: Perkumpulan
Endokrinologi Indonesia; 2015.
Ghimirey A, Sapkota B, Shrestha S, Basnet N, Shankar PR, Sapkota S,
et al. Evaluation of pharmacist counseling in improving knowledge,
attitude, and practice in chronic kidney disease patients. SAGE Open
Arjona Ferreira JC, Marre M, Barzilai N, Guo H, Golm GT, Sisk CM,
et al. Efficacy and safety of sitagliptin versus glipizide in patients with
Type 2 diabetes and moderate-to-severe chronic renal insufficiency.
Diabetes Care 2013;36:1067-73.
Gay EC, Cai Y, Gale SM, Baron A, Cruickshanks KJ, Kostraba JN,
et al. Smokers with IDDM experience excess morbidity. The Colorado
IDDM registry. Diabetes Care 1992;15:947-52.
Morisky DE, Munter P. New medication adherence scale versus
pharmacy fill rates in hypertensive seniors. Am J Manag Care
Puspitasari AW. The Effectiveness Analysis of Drug Booklet
Presentation on Adherence Level was Evaluated from Hemoglobin
Level (HbA1c) and Morisky Medication Adherence Scale (MMAS) -8
in Patients with Type 2 Diabetes Mellitus in Bakti Jaya Health Center.
Depok: Universitas Indonesia; 2012.
Yuniarti D. Evaluate Patient Adherence of type 2 Diabetes Mellitus
Through a Booklet that was Followed with the Patient in Beji and
Pancoran Mas Health Center. Depok: Universitas Indonesia; 2013.
Ministry of Health and National Institute of Health Research and
Development. National Report on Basic Health Raesearch, Riskesdas,
Jakarta: NIHRD; 2014.
Irawan D. Prevalence and Risk Factors for the Incidence of Type 2
Diabetes Mellitus in Urban Areas of Indonesia. Thesis. Jakarta: Faculty
of Public Health, Universitas Indonesia; 2010.
Nuryati S, Madanijah S, Atmarita A, Hardinsyah H. Lifestyle and
nutirional status and its relationship with diabetes mellitus in adult
women in Jakarta. Gizi Indones 2009;32:117.
Guariguata L, Whiting DR, Hambleton I, Beagley J, Linnenkamp U,
Shaw JE, et al. Global estimates of diabetes prevalence for 2013 and
projections for 2035. Diabetes Res Clin Pract 2014;103:137-49.
Dipiro JT, Well BG, Schwinghhammer TL, dan Dipiro CV.
Pharmacotherapy Handbook. 7th ed. USA: McGraw-Hill; 2015.
Presetiawati. Analysis of the Effectiveness of Giving Counceling and
Leaflet to the Decrease of the HbA1c Type 2 Diabetes Mellitus Patient.
Jakarta: Kabupaten Lebak; 2014.
World Health Organization. Adherence to Long-Term Therapies:
Evidence for Action. Geneva: World Health Organization; 2003.
Keban AJ. Evaluation of pharmacist educational outcome in patients
with Type 2 diabetes mellitus in Dr. Sardjito Hospital, Yogyakarta.
J Ilmu Kefarmasian Indones 2013;11:52-3.
Waspadji S. Diabetes Mellitus, Chronic Complications and Prevention.
Jakarta: FKUI; 2013.
Suh DC, Choi IS, Plauschinat C, Kwon J, Baron M. Impact of comorbid
conditions and race/ethnicity on glycemic control among the US
population with Type 2 diabetes, 1988-1994 to 1999-2004. J Diabetes
Battino M, Bompadre S, Politi A, Fioroni M, Rubini C, Bullon P, et al.
Antioxidant status (CoQ10 and vit. E levels) and immunohistochemical
analysis of soft tissues in periodontal diseases. Biofactors
Sullivan SD, Dalal MR, Burke JP. The impact of diabetes counseling
and education: Clinical and cost outcomes from a large population
of US managed care patients with Type 2 diabetes. Diabetes Educ
McCord AD. Clinical impact of a pharmacist-managed diabetes mellitus
drug therapy management service. Pharmacotherapy 2006;26:248-53.
Nishita C, Cardazone G, Uehara DL, Tom T. Empowered diabetes
management: Life coaching and pharmacist counseling for employed
adults with diabetes. Health Educ Behav 2013;40:581-91.
Suppapitiporn S, Chindavijak B, Onsanit S. Effect of diabetes
drug counseling by pharmacist, diabetic disease booklet and
special medication containers on glycemic control of Type 2
diabetes mellitus: A randomized controlled trial. J Med Assoc Thai
;88 Suppl 4:S134â€‘41.