HYPOGLYCEMIC ACTIVITY OF ETHANOLIC EXTRACT OF SAURAUIA VULCANI KORTH. LEAVES
DOI:
https://doi.org/10.22159/ajpcr.2018.v11s1.26561Keywords:
Hypoglycemic, Saurauia vulcani Korth, Leaves, Extract, EthanolAbstract
 Objective: The aim of this study was to investigate the hypoglycemic activity of ethanol extract of Saurauia vulcani Korth. leaves.
Methods: S. vulcani Korth. leaf powder was extracted by maceration method with ethanol 96%. Hypoglycemic activity was examined on rats which is induced with streptozotocin 40 mg/Kg body weight (BW) at dose of 50; 100; and 200 mg/Kg BW.
Results:Â Hypoglycemic activity of the extract in diabetic rats showed a significant reduction in blood glucose levels (p<0.001) at dosage 50 mg/Kg BW.
Conclusion: The results reveal that ethanol extract of S. vulcani Korth. leaves has hypoglycemic activity. Our further study is to assess mechanism action as antidiabetic.
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