• Dhanalakshmi Ravikumar Pot graduate
  • Mahesh Ramakrishna
  • Subramanian Emg
  • Vishnu Priya V
  • Gayathri R
  • Geetha Rv


Objectives: To compare the level of mutans streptococci in children with and without Early childhood caries (ECC) born to caries free mothers.
Methods: Twenty children aged between 3 and 6 years were selected depending on their caries experience, and the mother should be caries free in
both the groups. The children were divided into two groups. Group I had an active carious lesion and Group II were caries free. Saliva samples were
collected from the child and the mother in a sterile tube and bacterial culture was carried out to estimate the colony count.
Results: There was a highly significant difference in the colony forming unit (CFU) between the 2 groups, indicating higher CFU in children with ECC.
Conclusions: Even though there are higher chances of vertical transmission of MS from mother to their child, this study provides a new view that
mother alone is not a potential factor for mutans streptococci transmission to their child.
Keywords: Mutans streptocci, Early childhood caries, Colony forming unit.


Download data is not yet available.


. Mouradian WE. The face of a child: Children’s oral health and dental

education. J Dent Educ 2001;65(9):821-31.

Retnakumari N, Cyriac G. Childhood caries as influenced by

maternal and child characteristics in pre-school children of Kerala-an

epidemiological study. Contemp Clin Dent 2012;3(1):2-8.

Amoroso P, Avila FA, Gagliardi CM. Prevalence of different

Streptococci species in the oral cavity of children and adolescents. Braz

J Oral Sci 2003;2(4):164-8.

Caufield PW, Cutter GR, Dasanayake AP. Initial acquisition of mutans

streptococci by infants: Evidence for a discrete window of infectivity.

J Dent Res 1993;72(1):37-45.

Florio FM, Klein MI, Pereira AC, Goncalves BR. Time of initial

acquisition of mutans streptococci by human infants. J Clin Pediatr

Dent 2004;28(4):303-8.

Berkowitz R. Etiology of nursing caries: A microbiologic perspective.

J Public Health Dent 1996;56(1):51-4.

Lindquist B, Emilson CG. Colonization of Streptococcus mutans and

Streptococcus sobrinus genotypes and caries development in children

to mothers harboring both species. Caries Res 2004;38(2):95-103.

Chaffee BW, Gansky SA, Weintraub JA, Featherstone JD,

Ramos-Gomez FJ. Maternal oral bacterial levels predict early childhood

caries development. J Dent Res 2014;93(3):238-44.

Rosenblatt R, Steinberg D, Mankuta D, Zini A. Acquired oral

microflora of new-borns during the first 48 hours of life. J Clin Pediatr

Dent 2015;39(5):442-6.

Ramamurthy PH, Swamy HS, Bennete F, Rohini M, Nagarathnamma T.

Relationship between severe-early childhood caries, salivary

mutans streptococci, and Lactobacilli in preschool children of low

socioeconomic status in Bengaluru city. J Indian Soc Pedod Prev Dent


Ripa LW. Nursing caries: A comprehensive review. Pediatr Dent


Slavkin HC. Streptococcus mutans, early childhood caries and new

opportunities. J Am Dent Assoc 1999;130(12):1787-92.

Freedman M, Birked D, Granath K. Analyses of glucans from cariogenic

and mutant Streptococcus mutans. Infect Immun 1978;21(1):17-27.

Spatafora G, Rohrer K, Barnard D, Michalek S. A Streptococcus mutans

mutant that synthesizes elevated levels of intracellular polysaccharide

is hypercariogenic in vivo. Infect Immun 1995;63(7):2556-63.

Köhler B, Bratthall D. Intrafamilial levels of Streptococcus mutans

and some aspects of the bacterial transmission. Scand J Dent Res


Berkowitz RJ, Turner J, Green P. Primary oral infection of infants with

Streptococcus mutans. Arch Oral Biol 1980;25(4):221-4.

Broadbent JM, Thomson WM. For debate: Problems with the DMF

index pertinent to dental caries data analysis. Community Dent Oral

Epidemiol 2005;33(6):400-9.

Monse B, Heinrich-Weltzien R, Benzian H, Holmgren C, van Palenstein

Helderman W. PUFA – An index of clinical consequences of untreated

dental caries. Community Dent Oral Epidemiol 2010;38(1):77-82.

Shifa S, Muthu MS, Amarlal D, Rathna Prabhu V. Quantitative

assessment of IgA levels in the unstimulated whole saliva of caries-

free and caries-active children. J Indian Soc Pedod Prev Dent


Cheaib Z, Lussi A. Role of amylase, mucin, IgA and albumin on salivary

protein buffering capacity: A pilot study. J Biosci 2013;38(2):259-65.

Nakano K, Nomura R, Shimizu N, Nakagawa I, Hamada S,

Ooshima T. Development of a PCR method for rapid identification

of new Streptococcus mutans serotype k strains. J Clin Microbiol




How to Cite

Ravikumar, D., M. Ramakrishna, S. Emg, V. Priya V, G. R, and G. Rv. “COMPARATIVE EVALUATION OF ORAL MICROBIOTA OF CHILDREN WITH AND WITHOUT EARLY CHILDHOOD CARIES BORN TO CARIES FREE MOTHERS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 9, no. 3, May 2016, pp. 212-4,



Original Article(s)

Most read articles by the same author(s)

1 2 > >>