PRELIMINARY PHYTOCHEMICAL ANALYSIS AND CYTOTOXICITY POTENTIAL OF PINEAPPLE EXTRACT ON ORAL CANCER CELL LINES
DOI:
https://doi.org/10.22159/ajpcr.2016.v9s2.13313Abstract
ABSTRACT
Objective: This study aims at performing a preliminary phytochemical analysis to evaluate the phytochemical composition of pineapple extract and
its cytotoxicity potential on oral cancer cell lines.
Methods: Preliminary phytochemical analysis of pineapple extract was done, 3-(4, 5-Dimethyl-2-thiazolyl)-2, 5-diphenyl-2H-tetrazolium bromide
assay for evaluating the cytotoxicity potential of the extract on oral cancer cell lines was performed.
Results: Phytoconstituents such as flavonoids, coumarins, and phenols were present in the pineapple extract. The extract also exhibited increased
cytotoxicity with increased concentration.
Conclusion: This study is conducted to see if pineapple extract is effective in treating oral cancer in a natural way instead of harmful treatments.
Keywords: Cytotoxicity, Pineapple extract, Anticancer drug.
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