PATCHES FOR ACNE TREATMENT: AN UPDATE ON THE FORMULATION AND STABILITY TEST
DOI:
https://doi.org/10.22159/ijap.2021.v13s4.43812Keywords:
Acne vulgaris, Acne patches, Microneedle patches, Hydrogel patches, Hydrocolloid patches, StabilityAbstract
The purpose of this article review was to find out more about acne patch formulations and test stability. The method used is searching data from various articles based on Google Scholar, Elsevier, and Molecules with the keywords "Acne vulgaris, acne treatment, acne patches, and types of acne patches” and with a range of years between 2011 and 2021. Based on the type of acne, acne patches are divided into several types, namely microneedle patches, acne medicine patches, and hydrocolloid patches. The results obtained in this review show that the most commonly used acne patch is the medicated acne patch (hydrogel patches), because of its waterproof property to protect acne from secondary infection, it can absorb liquid inside and flatten acne and is cheaper compared to microneedles. The hydrogel patch is also stable at a temperature of 40±2 °C and a relative humidity (RH) of 75±5% for 6 mo of storage.
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References
NCBI. Acne vulgaris [internet]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK459173. [Last accessed on 03 Jun 2021]
Zaenglein AL. Acne vulgaris. N Engl J Med. 2018;379(14):1343-52. doi: 10.1056/NEJMcp1702493, PMID 30281982.
Fox L, Csongradi C, Aucamp M, Du Plessis J, Gerber M. Treatment modalities for acne. Molecules. 2016;21(8):1-20. doi: 10.3390/molecules21081063, PMID 27529209.
Office of Women’s Health (OASH). Acne [internet]. Gov/a-z-topics/acne. Available from: https://www.womenshealth. [Last accessed on 03 Jun 2021]
Zaenglein AL, Pathy AL, Schlosser BJ, Alikhan A, Baldwin HE, Berson DS, Bowe WP, Graber EM, Harper JC, Kang S, Keri JE, Leyden JJ, Reynolds RV, Silverberg NB, Stein Gold LF, Tollefson MM, Weiss JS, Dolan NC, Sagan AA, Stern M, Boyer KM, Bhushan R. Guidelines of care for the management of acne vulgaris. J Am Acad Dermatol. 2016;74(5):945-73.e33. doi: 10.1016/j.jaad.2015.12.037, PMID 26897386.
Eisenberg MJ, Afilalo J, Lawler PR, Abrahamowicz M, Richard H, Pilote L. Cancer risk related to low-dose ionizing radiation from cardiac imaging in patients after acute myocardial infarction. CMAJ. 2011;183(4):430-6. doi: 10.1503/cmaj.100463, PMID 21324846.
American Academy of Dermatologi. Association (AAD). Acne clinical guideline [internet]. Available from: https://www.aad.org/member/clinical-quality/guidelines/acne. [Last accessed on 03 Jun 2021]
Russell JJ. Topical therapy for acne. Am Fam Physician. 2000;61(2):357-66. PMID 10670502.
Titus S, Hodge J. Diagnosis and treatment of acne. Am Fam Physician. 2012;86(8):734-40. PMID 23062156.
Zhang Y, Feng P, Yu J, Yang J, Zhao J, Wang J, Shen Q, Gu Z. ROS-responsive microneedle patch for acne vulgaris treatment. Adv Therap. 2018;1(3). doi: 10.1002/adtp.201800035, PMID 1800035.
Li Y, Zhang H, Yang R, Laffitte Y, Schmill U, Hu W, Kaddoura M, Blondeel EJM, Cui B. Fabrication of sharp silicon hollow microneedles by deep-reactive ion etching towards minimally invasive diagnostics. Microsyst Nanoeng. 2019;5:41. doi: 10.1038/s41378-019-0077-y, PMID 31636931.
Pastore MN, Kalia YN, Horstmann M, Roberts MS. Transdermal patches: history, development and pharmacology. Br J Pharmacol. 2015;172(9):2179-209. doi: 10.1111/bph.13059, PMID 25560046.
Kapao N, Wattanutchariya W. Development of natural acne patch from local materials using quality function deployment technique. MATEC Web Conf. 2018;192:4-7. doi: 10.1051/matecconf/201819201050.
Kuo CW, Chiu YF, Wu MH, Li MH, Wu CN, Chen WS, Huang CH. Gelatin/chitosan bilayer patches loaded with cortex Phellodendron amurense/centella asiatica extracts for anti-acne application. Polymers. 2021;13(4):1-15. doi: 10.3390/polym13040579, PMID 33671908.
Health line. From medicated to microneedle: 9 acne patches to try [internet]. Available from: https://www.healthline. communhealth/beauty-skin-care/acne-patches. [Last accessed on 03 Jun 2021].
Zhang T, Sun B, Guo J, Wang M, Cui H, Mao H, Wang B, Yan F. Active pharmaceutical ingredient poly(ionic liquid)-based microneedles for the treatment of skin acne infection. Acta Biomater. 2020;115:136-47. doi: 10.1016/j.actbio. 2020.08. 023, PMID 32853804.
Dharadhar S, Majumdar A, Dhoble S, Patravale V. Microneedles for transdermal drug delivery: a systematic review. Drug Dev Ind Pharm. 2019;45(2):188-201. doi: 10.1080/ 03639045.2018.1539497, PMID 30348022.
Tucak A, Sirbubalo M, Hindija L, Rahic O, Hadziabdic J, Muhamedagic K, Cekic A, Vranic E. Microneedles: characteristics, materials, production methods and commercial development. Micromachines. 2020;11(11):1-30. doi: 10.3390/mi11110961, PMID 33121041.
Bariya SH, Gohel MC, Mehta TA, Sharma OP. Microneedles: an emerging transdermal drug delivery system. J Pharm Pharmacol. 2012;64(1):11-29. doi: 10.1111/j.2042-7158.2011. 01369.x, PMID 22150668.
Ita K. Ceramic microneedles and hollow microneedles for transdermal drug delivery: two decades of research. J Drug Deliv Sci Technol. 2018;44:314-22. doi: 10.1016/ j.jddst.2018.01.004.
Waghule T, Singhvi G, Dubey SK, Pandey MM, Gupta G, Singh M, Dua K. Microneedles: A smart approach and increasing potential for transdermal drug delivery system. Biomed Pharmacother. 2019;109:1249-58. doi: 10.1016/j.biopha. 2018.10.078, PMID 30551375.
Mandal A, Clegg JR, Anselmo AC, Mitragotri S. Hydrogels in the clinic. Bioeng Transl Med. 2020;5(2):e10158. doi: 10.1002/btm2.10158, PMID 32440563.
Wang W, Narain R, Chapter ZH. 10-hydrogels. Polym Sci Nanotechnol. 2020;10:203-44.
Lee TW, Kim JC, Hwang SJ. Hydrogel patches containing triclosan for acne treatment. Eur J Pharm Biopharm. 2003;56(3):407-12. doi: 10.1016/s0939-6411(03)00137-1, PMID 14602184.
Garg S, Garg A, Vishwavidyalaya RD. Hydrogel: classification, properties, preparation and technical features. Asian J Biomaterial Res. 2016;2:163-70.
Narayanaswamy R, Torchilin VP. Hydrogels and their applications in targeted drug delivery. Molecules. 2019;24(3):603. doi: 10.3390/molecules24030603, PMID 30744011.
Rowe RC, Sheskey PJ. Handbook of pharmaceutical excipients. USA: Pharmaceutical Press; 2009.
De Paepe K, Wibaux A, Ward C, Rogiers V. Skin efficacy and biophysical assessment of glycerol-containing hydrocolloid patches. Skin Pharmacol Physiol. 2009;22(5):258-65. doi: 10.1159/000235553, PMID 19690451.
Banerjee S, Chattopadhyay P, Ghosh A, Bhattacharya SS, Kundu A, Veer V. Accelerated stability testing of a transdermal patch composed of eserine and pralidoxime chloride for prophylaxis against (±)-anatoxin A poisoning. J Food Drug Anal. 2014;22(2):264-70. doi: 10.1016/j.jfda.2014.01.022.
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